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Cicatricial entropion

MedGen UID:
509840
•Concept ID:
C0155191
•
Disease or Syndrome
Synonym: cicatricial entropion
SNOMED CT: Cicatricial entropion (67383002)
 
HPO: HP:0031737
Monarch Initiative: MONDO:0001637

Definition

Abnormal inversion (turning inward) of the eyelid towards the globe associated with scarring that vertically shortens the posterior lamella of the eyelid. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCicatricial entropion

Professional guidelines

PubMed

Management of Severe Cicatricial Entropion With Labial Mucous Membrane Graft in Cicatricial Ocular Surface Disorders.
Osaki TH, Sant'Anna AE, Osaki MH, Kikkawa DO, Yabumoto C, Yang P, Korn BS
J Craniofac Surg 2018 Sep;29(6):1531-1534. doi: 10.1097/SCS.0000000000004584. PMID: 29762330
Management of patients with confirmed and presumed mucous membrane pemphigoid undergoing entropion repair.
Gibbons A, Johnson TE, Wester ST, Gonzalez AE, Farias CC, Betancurt C, Amescua G, Perez VL
Am J Ophthalmol 2015 May;159(5):846-52.e2. Epub 2015 Jan 31 doi: 10.1016/j.ajo.2015.01.028. PMID: 25644537
Eyelid complications in trachoma: diagnosis and management.
Nasr AM
Acta Ophthalmol (Copenh) 1991 Apr;69(2):200-4. doi: 10.1111/j.1755-3768.1991.tb02711.x. PMID: 1872138

Recent clinical studies

Etiology

Cicatricial Entropion in Chronic Cicatrizing Conjunctivitis: Potential Pathophysiologic Mechanisms and Long-Term Outcomes of a Modified Technique.
Singh S, Basu S, Jakati S
Ophthalmic Plast Reconstr Surg 2023 Nov-Dec 01;39(6):563-569. Epub 2023 May 4 doi: 10.1097/IOP.0000000000002400. PMID: 37145030
Combined Surgical Strategies Adjusted to Clinical Evaluations for Severe Upper Eyelid Cicatricial Entropion and Trichiasis.
Zhang L, Hou Z, Li Y, Li D
J Craniofac Surg 2023 Mar-Apr 01;34(2):764-767. Epub 2023 Jan 13 doi: 10.1097/SCS.0000000000009170. PMID: 36635852
A conjunctival-sparing surgical technique for lower eyelid cicatricial entropion repair in ocular cicatricial pemphigoid.
Choung H, Reshef ER, Tanking T, Freitag SK
Orbit 2020 Feb;39(1):23-30. Epub 2019 Feb 7 doi: 10.1080/01676830.2019.1573434. PMID: 30732510
Graft versus host disease: what should the oculoplastic surgeon know?
Tung CI
Curr Opin Ophthalmol 2017 Sep;28(5):499-504. doi: 10.1097/ICU.0000000000000400. PMID: 28598869
Cicatricial entropion repair with hard palate mucous membrane graft: surgical technique and outcomes.
Swamy BN, Benger R, Taylor S
Clin Exp Ophthalmol 2008 May;36(4):348-52. doi: 10.1111/j.1442-9071.2008.01697.x. PMID: 18700922

Diagnosis

Cicatricial Entropion in Chronic Cicatrizing Conjunctivitis: Potential Pathophysiologic Mechanisms and Long-Term Outcomes of a Modified Technique.
Singh S, Basu S, Jakati S
Ophthalmic Plast Reconstr Surg 2023 Nov-Dec 01;39(6):563-569. Epub 2023 May 4 doi: 10.1097/IOP.0000000000002400. PMID: 37145030
Severe cicatricial entropion repair using mucous membrane graft in Stevens-Johnson syndrome.
Adewara B, Singh S
Indian J Ophthalmol 2022 Dec;70(12):4470. doi: 10.4103/ijo.IJO_1504_22. PMID: 36453379Free PMC Article
Alkali Burn Over a LASIK Flap.
Witsberger EM, Patel SV
Cornea 2021 Jul 1;40(7):907-909. doi: 10.1097/ICO.0000000000002604. PMID: 33273190
Observations on Prostaglandin Orbitopathy.
Custer PL, Kent TL
Ophthalmic Plast Reconstr Surg 2016 Mar-Apr;32(2):102-5. doi: 10.1097/IOP.0000000000000431. PMID: 25719374
Trichiasis.
Ferreira IS, Bernardes TF, Bonfioli AA
Semin Ophthalmol 2010 May;25(3):66-71. doi: 10.3109/08820538.2010.488580. PMID: 20590415

Therapy

Alkali Burn Over a LASIK Flap.
Witsberger EM, Patel SV
Cornea 2021 Jul 1;40(7):907-909. doi: 10.1097/ICO.0000000000002604. PMID: 33273190
Graft versus host disease: what should the oculoplastic surgeon know?
Tung CI
Curr Opin Ophthalmol 2017 Sep;28(5):499-504. doi: 10.1097/ICU.0000000000000400. PMID: 28598869
Observations on Prostaglandin Orbitopathy.
Custer PL, Kent TL
Ophthalmic Plast Reconstr Surg 2016 Mar-Apr;32(2):102-5. doi: 10.1097/IOP.0000000000000431. PMID: 25719374
Cicatricial entropion following docetaxel (Taxotere) therapy.
Cetinkaya A, Hudak D, Kulwin D
Ophthalmic Plast Reconstr Surg 2011 Sep-Oct;27(5):e113-6. doi: 10.1097/IOP.0b013e318201ca26. PMID: 21283030
Complications of blepharopigmentation.
Goldberg RA, Shorr N
Ophthalmic Surg 1989 Jun;20(6):420-3. PMID: 2748085

Prognosis

A conjunctival-sparing surgical technique for lower eyelid cicatricial entropion repair in ocular cicatricial pemphigoid.
Choung H, Reshef ER, Tanking T, Freitag SK
Orbit 2020 Feb;39(1):23-30. Epub 2019 Feb 7 doi: 10.1080/01676830.2019.1573434. PMID: 30732510
Modified tarsotomy for the treatment of severe cicatricial entropion.
Chi M, Kim HJ, Vagefi R, Kersten RC
Eye (Lond) 2016 Jul;30(7):992-7. Epub 2016 Apr 22 doi: 10.1038/eye.2016.77. PMID: 27101749Free PMC Article
Anterior lamellar recession, blepharoplasty, and supratarsal fixation for cicatricial upper eyelid entropion without lagophthalmos.
Aghai GH, Gordiz A, Falavarjani KG, Kashkouli MB
Eye (Lond) 2016 Apr;30(4):627-31. Epub 2016 Feb 12 doi: 10.1038/eye.2016.12. PMID: 26869158Free PMC Article
Shared buccal mucosal graft for simultaneous repair of severe upper and lower eyelid cicatricial entropion.
Kerr T, Mancini R
Orbit 2016;35(1):24-8. Epub 2015 Dec 28 doi: 10.3109/01676830.2015.1099693. PMID: 26710260
Outcomes of lower eyelid cicatricial entropion with grey-line split, retractor recession, lateral-horn lysis, and anterior lamella repositioning.
Malhotra R, Yau C, Norris JH
Ophthalmic Plast Reconstr Surg 2012 Mar-Apr;28(2):134-9. doi: 10.1097/IOP.0b013e3182467c11. PMID: 22410661

Clinical prediction guides

The upper eyelid levator weakening procedure for the correction of severe cicatricial entropion caused by trachoma.
Wang Y, Yuan Y, Pang L, Qiu B, Su D, Guan X, Xiang X, Li J
Ann Palliat Med 2020 Nov;9(6):4113-4118. doi: 10.21037/apm-20-2067. PMID: 33302671
Management of Severe Cicatricial Entropion With Labial Mucous Membrane Graft in Cicatricial Ocular Surface Disorders.
Osaki TH, Sant'Anna AE, Osaki MH, Kikkawa DO, Yabumoto C, Yang P, Korn BS
J Craniofac Surg 2018 Sep;29(6):1531-1534. doi: 10.1097/SCS.0000000000004584. PMID: 29762330
Anterior lamellar recession, blepharoplasty, and supratarsal fixation for cicatricial upper eyelid entropion without lagophthalmos.
Aghai GH, Gordiz A, Falavarjani KG, Kashkouli MB
Eye (Lond) 2016 Apr;30(4):627-31. Epub 2016 Feb 12 doi: 10.1038/eye.2016.12. PMID: 26869158Free PMC Article
Observations on Prostaglandin Orbitopathy.
Custer PL, Kent TL
Ophthalmic Plast Reconstr Surg 2016 Mar-Apr;32(2):102-5. doi: 10.1097/IOP.0000000000000431. PMID: 25719374
Management of upper eyelid cicatricial entropion.
Ross AH, Cannon PS, Selva D, Malhotra R
Clin Exp Ophthalmol 2011 Aug;39(6):526-36. Epub 2011 Mar 24 doi: 10.1111/j.1442-9071.2011.02503.x. PMID: 21819506

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