U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neonatal thyrotoxicosis

MedGen UID:
510684
Concept ID:
C0158983
Disease or Syndrome
Synonyms: infantile hyperthyroidism; Neonatal Thyrotoxicosis; neonatal thyrotoxicosis
SNOMED CT: Neonatal thyrotoxicosis (13795004)
 
Monarch Initiative: MONDO:0001555

Definition

A hypermetabolic syndrome characterized by tachycardia, palpitations, tremor, weight loss, and moist skin that is caused by the elevation of thyroid hormone levels in the serum of the newborn infant or thyroid-axis receptor activation, most commonly due to transplacental passage of thyroid stimulating globulins. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeonatal thyrotoxicosis

Professional guidelines

PubMed

Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M
J Clin Endocrinol Metab 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. PMID: 34894265
Hesarghatta Shyamasunder A, Abraham P
Clin Endocrinol (Oxf) 2017 May;86(5):652-657. doi: 10.1111/cen.13327. PMID: 28295509
Barbesino G, Tomer Y
J Clin Endocrinol Metab 2013 Jun;98(6):2247-55. Epub 2013 Mar 28 doi: 10.1210/jc.2012-4309. PMID: 23539719Free PMC Article

Recent clinical studies

Etiology

Abdullah AA, Ramli N, Yaacob NM, Hussain S
J ASEAN Fed Endocr Soc 2022;37(2):15-22. Epub 2022 Aug 6 doi: 10.15605/jafes.037.02.03. PMID: 36578895Free PMC Article
Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M
J Clin Endocrinol Metab 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. PMID: 34894265
Kotwal A, Stan M
Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S20-S27. doi: 10.1097/IOP.0000000000001052. PMID: 29771756
Smith C, Thomsett M, Choong C, Rodda C, McIntyre HD, Cotterill AM
Clin Endocrinol (Oxf) 2001 Mar;54(3):371-6. doi: 10.1046/j.1365-2265.2001.01173.x. PMID: 11298090
Glinoer D
Thyroid 1998 Sep;8(9):859-64. doi: 10.1089/thy.1998.8.859. PMID: 9777758

Diagnosis

Bohîlțea RE, Mihai BM, Szini E, Șucaliuc IA, Badiu C
Medicina (Kaunas) 2022 Dec 23;59(1) doi: 10.3390/medicina59010036. PMID: 36676660Free PMC Article
Abdullah AA, Ramli N, Yaacob NM, Hussain S
J ASEAN Fed Endocr Soc 2022;37(2):15-22. Epub 2022 Aug 6 doi: 10.15605/jafes.037.02.03. PMID: 36578895Free PMC Article
Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M
J Clin Endocrinol Metab 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. PMID: 34894265
Kotwal A, Stan M
Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S20-S27. doi: 10.1097/IOP.0000000000001052. PMID: 29771756
Cooper DS, Laurberg P
Lancet Diabetes Endocrinol 2013 Nov;1(3):238-49. Epub 2013 Oct 18 doi: 10.1016/S2213-8587(13)70086-X. PMID: 24622372

Therapy

Ravindra S, Shetty S
BMJ Case Rep 2022 Mar 9;15(3) doi: 10.1136/bcr-2021-247865. PMID: 35264385Free PMC Article
Samuels SL, Namoc SM, Bauer AJ
Clin Perinatol 2018 Mar;45(1):31-40. Epub 2017 Dec 16 doi: 10.1016/j.clp.2017.10.001. PMID: 29406005
Hesarghatta Shyamasunder A, Abraham P
Clin Endocrinol (Oxf) 2017 May;86(5):652-657. doi: 10.1111/cen.13327. PMID: 28295509
Cooper DS, Laurberg P
Lancet Diabetes Endocrinol 2013 Nov;1(3):238-49. Epub 2013 Oct 18 doi: 10.1016/S2213-8587(13)70086-X. PMID: 24622372
Smith C, Thomsett M, Choong C, Rodda C, McIntyre HD, Cotterill AM
Clin Endocrinol (Oxf) 2001 Mar;54(3):371-6. doi: 10.1046/j.1365-2265.2001.01173.x. PMID: 11298090

Prognosis

Bohîlțea RE, Mihai BM, Szini E, Șucaliuc IA, Badiu C
Medicina (Kaunas) 2022 Dec 23;59(1) doi: 10.3390/medicina59010036. PMID: 36676660Free PMC Article
Ravindra S, Shetty S
BMJ Case Rep 2022 Mar 9;15(3) doi: 10.1136/bcr-2021-247865. PMID: 35264385Free PMC Article
Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M
J Clin Endocrinol Metab 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. PMID: 34894265
Kotwal A, Stan M
Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S20-S27. doi: 10.1097/IOP.0000000000001052. PMID: 29771756
Smith C, Thomsett M, Choong C, Rodda C, McIntyre HD, Cotterill AM
Clin Endocrinol (Oxf) 2001 Mar;54(3):371-6. doi: 10.1046/j.1365-2265.2001.01173.x. PMID: 11298090

Clinical prediction guides

Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M
J Clin Endocrinol Metab 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. PMID: 34894265
Kotwal A, Stan M
Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S20-S27. doi: 10.1097/IOP.0000000000001052. PMID: 29771756
Barbesino G, Tomer Y
J Clin Endocrinol Metab 2013 Jun;98(6):2247-55. Epub 2013 Mar 28 doi: 10.1210/jc.2012-4309. PMID: 23539719Free PMC Article
Smith C, Thomsett M, Choong C, Rodda C, McIntyre HD, Cotterill AM
Clin Endocrinol (Oxf) 2001 Mar;54(3):371-6. doi: 10.1046/j.1365-2265.2001.01173.x. PMID: 11298090
Glinoer D
Thyroid 1998 Sep;8(9):859-64. doi: 10.1089/thy.1998.8.859. PMID: 9777758

Recent systematic reviews

van Dijk MM, Smits IH, Fliers E, Bisschop PH
Thyroid 2018 Feb;28(2):257-264. doi: 10.1089/thy.2017.0413. PMID: 29325496

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...