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Fusobacterium Infection

MedGen UID:
5295
•Concept ID:
C0016879
•
Disease or Syndrome
Synonyms: Fusobacterium Infections; Infection, Fusobacterium; Infection, Sphaerophorus; Infections, Fusobacterium; Infections, Sphaerophorus; Sphaerophorus Infection; Sphaerophorus Infections

Definition

Infection with anaerobic gram-negative bacteria of the genus Fusobacterium. It results in abscess formation and tissue damage. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFusobacterium Infection

Professional guidelines

PubMed

Intestinal bacteria and colorectal cancer: etiology and treatment.
Dougherty MW, Jobin C
Gut Microbes 2023 Jan-Dec;15(1):2185028. doi: 10.1080/19490976.2023.2185028. PMID: 36927206Free PMC Article
Management of pediatric head and neck infections in the emergency department.
Abudinen-Vasquez S, Marin MN
Pediatr Emerg Med Pract 2020 Nov;17(11):1-24. Epub 2020 Nov 2 PMID: 33105074
Microbiology and treatment of acute apical abscesses.
Siqueira JF Jr, Rôças IN
Clin Microbiol Rev 2013 Apr;26(2):255-73. doi: 10.1128/CMR.00082-12. PMID: 23554416Free PMC Article

Recent clinical studies

Etiology

Invasive Fusobacterium Infections in Children: A Retrospective Multicenter Study.
Hirschhorn A, Averbuch D, Michaan N, Adler A, Grisaru-Soen G
Pediatr Infect Dis J 2022 Jul 1;41(7):517-523. Epub 2022 Jun 7 doi: 10.1097/INF.0000000000003514. PMID: 35363651
Surgical intervention for acute mastoiditis: 10 years experience in a tertiary children hospital.
Stern Shavit S, Raveh E, Levi L, Sokolov M, Ulanovski D
Eur Arch Otorhinolaryngol 2019 Nov;276(11):3051-3056. Epub 2019 Aug 27 doi: 10.1007/s00405-019-05606-2. PMID: 31456037
Bumble Foot: A Rare Presentation of a Fusobacterium varium Infection of the Heel Pad in a Healthy Female.
Stransky O, Blum R, Brown W, Kruse D, Stone P
J Foot Ankle Surg 2016 Sep-Oct;55(5):1087-90. Epub 2015 Oct 9 doi: 10.1053/j.jfas.2015.08.015. PMID: 26456575
Fusobacterium invasive infections in children: a retrospective study in two French tertiary care centres.
Bailhache M, Mariani-Kurkdjian P, Lehours P, Sarlangue J, Pillet P, Bingen E, Faye A
Eur J Clin Microbiol Infect Dis 2013 Aug;32(8):1041-7. Epub 2013 Mar 8 doi: 10.1007/s10096-013-1848-2. PMID: 23471481

Diagnosis

Invasive Fusobacterium Infections in Children: A Retrospective Multicenter Study.
Hirschhorn A, Averbuch D, Michaan N, Adler A, Grisaru-Soen G
Pediatr Infect Dis J 2022 Jul 1;41(7):517-523. Epub 2022 Jun 7 doi: 10.1097/INF.0000000000003514. PMID: 35363651
Surgical intervention for acute mastoiditis: 10 years experience in a tertiary children hospital.
Stern Shavit S, Raveh E, Levi L, Sokolov M, Ulanovski D
Eur Arch Otorhinolaryngol 2019 Nov;276(11):3051-3056. Epub 2019 Aug 27 doi: 10.1007/s00405-019-05606-2. PMID: 31456037
Bumble Foot: A Rare Presentation of a Fusobacterium varium Infection of the Heel Pad in a Healthy Female.
Stransky O, Blum R, Brown W, Kruse D, Stone P
J Foot Ankle Surg 2016 Sep-Oct;55(5):1087-90. Epub 2015 Oct 9 doi: 10.1053/j.jfas.2015.08.015. PMID: 26456575
Incomplete Lemierre syndrome.
Shiber J, Fontane E, Rabinowitz R, Gens D, Habashi N, Scalea T
Pediatr Emerg Care 2015 Jan;31(1):39-41. doi: 10.1097/PEC.0000000000000327. PMID: 25560619
Neurologic manifestations of Fusobacterium infections in children.
Megged O, Assous MV, Miskin H, Peleg U, Schlesinger Y
Eur J Pediatr 2013 Jan;172(1):77-83. Epub 2012 Sep 27 doi: 10.1007/s00431-012-1847-9. PMID: 23015047

Therapy

Invasive Fusobacterium Infections in Children: A Retrospective Multicenter Study.
Hirschhorn A, Averbuch D, Michaan N, Adler A, Grisaru-Soen G
Pediatr Infect Dis J 2022 Jul 1;41(7):517-523. Epub 2022 Jun 7 doi: 10.1097/INF.0000000000003514. PMID: 35363651
Surgical intervention for acute mastoiditis: 10 years experience in a tertiary children hospital.
Stern Shavit S, Raveh E, Levi L, Sokolov M, Ulanovski D
Eur Arch Otorhinolaryngol 2019 Nov;276(11):3051-3056. Epub 2019 Aug 27 doi: 10.1007/s00405-019-05606-2. PMID: 31456037
Bumble Foot: A Rare Presentation of a Fusobacterium varium Infection of the Heel Pad in a Healthy Female.
Stransky O, Blum R, Brown W, Kruse D, Stone P
J Foot Ankle Surg 2016 Sep-Oct;55(5):1087-90. Epub 2015 Oct 9 doi: 10.1053/j.jfas.2015.08.015. PMID: 26456575
Incomplete Lemierre syndrome.
Shiber J, Fontane E, Rabinowitz R, Gens D, Habashi N, Scalea T
Pediatr Emerg Care 2015 Jan;31(1):39-41. doi: 10.1097/PEC.0000000000000327. PMID: 25560619
Fusobacterium invasive infections in children: a retrospective study in two French tertiary care centres.
Bailhache M, Mariani-Kurkdjian P, Lehours P, Sarlangue J, Pillet P, Bingen E, Faye A
Eur J Clin Microbiol Infect Dis 2013 Aug;32(8):1041-7. Epub 2013 Mar 8 doi: 10.1007/s10096-013-1848-2. PMID: 23471481

Prognosis

Surgical intervention for acute mastoiditis: 10 years experience in a tertiary children hospital.
Stern Shavit S, Raveh E, Levi L, Sokolov M, Ulanovski D
Eur Arch Otorhinolaryngol 2019 Nov;276(11):3051-3056. Epub 2019 Aug 27 doi: 10.1007/s00405-019-05606-2. PMID: 31456037
Bumble Foot: A Rare Presentation of a Fusobacterium varium Infection of the Heel Pad in a Healthy Female.
Stransky O, Blum R, Brown W, Kruse D, Stone P
J Foot Ankle Surg 2016 Sep-Oct;55(5):1087-90. Epub 2015 Oct 9 doi: 10.1053/j.jfas.2015.08.015. PMID: 26456575
Incomplete Lemierre syndrome.
Shiber J, Fontane E, Rabinowitz R, Gens D, Habashi N, Scalea T
Pediatr Emerg Care 2015 Jan;31(1):39-41. doi: 10.1097/PEC.0000000000000327. PMID: 25560619
Fusobacterium detected in colonic biopsy and clinicopathological features of ulcerative colitis in Japan.
Tahara T, Shibata T, Kawamura T, Okubo M, Ichikawa Y, Sumi K, Miyata M, Ishizuka T, Nakamura M, Nagasaka M, Nakagawa Y, Ohmiya N, Arisawa T, Hirata I
Dig Dis Sci 2015 Jan;60(1):205-10. Epub 2014 Aug 8 doi: 10.1007/s10620-014-3316-y. PMID: 25102986

Clinical prediction guides

Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts.
Muraoka A, Suzuki M, Hamaguchi T, Watanabe S, Iijima K, Murofushi Y, Shinjo K, Osuka S, Hariyama Y, Ito M, Ohno K, Kiyono T, Kyo S, Iwase A, Kikkawa F, Kajiyama H, Kondo Y
Sci Transl Med 2023 Jun 14;15(700):eadd1531. doi: 10.1126/scitranslmed.add1531. PMID: 37315109
Fusobacterium detected in colonic biopsy and clinicopathological features of ulcerative colitis in Japan.
Tahara T, Shibata T, Kawamura T, Okubo M, Ichikawa Y, Sumi K, Miyata M, Ishizuka T, Nakamura M, Nagasaka M, Nakagawa Y, Ohmiya N, Arisawa T, Hirata I
Dig Dis Sci 2015 Jan;60(1):205-10. Epub 2014 Aug 8 doi: 10.1007/s10620-014-3316-y. PMID: 25102986

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