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Toe pain

MedGen UID:
537055
•Concept ID:
C0241416
•
Sign or Symptom
Synonym: Pain in toe
SNOMED CT: Toe pain (285365001); Pain in toe (285365001)
 
HPO: HP:0030841

Definition

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the toe. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVToe pain

Professional guidelines

PubMed

Diagnosis and conservative management of great toe pathologies: a review.
Andrews NA, Ray J, Dib A, Harrelson WM, Khurana A, Singh MS, Shah A
Postgrad Med 2021 May;133(4):409-420. Epub 2021 Apr 4 doi: 10.1080/00325481.2021.1895587. PMID: 33622169
Management of acute lesser toe pain.
Ray J, Andrews NA, Dib A, Harrelson WM, Khurana A, Singh MS, Shah A
Postgrad Med 2021 Apr;133(3):320-329. Epub 2021 Jan 18 doi: 10.1080/00325481.2021.1873581. PMID: 33406375
Diagnosis, management, and complications of glomus tumours of the digits in neurofibromatosis type 1.
Stewart DR, Sloan JL, Yao L, Mannes AJ, Moshyedi A, Lee CC, Sciot R, De Smet L, Mautner VF, Legius E
J Med Genet 2010 Aug;47(8):525-32. Epub 2010 Jun 7 doi: 10.1136/jmg.2009.073965. PMID: 20530151Free PMC Article

Recent clinical studies

Etiology

Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults.
Clarke GR, Thomas MJ, Rathod-Mistry T, Marshall M, Menz HB, Peat G, Roddy E
Musculoskeletal Care 2020 Sep;18(3):383-390. Epub 2020 Apr 20 doi: 10.1002/msc.1472. PMID: 32311212
A Rare Combination of CYP2C9*3/*3 and VKORC1 1639AA in a Patient Who Had Myxoma and Thromboembolism.
Son KH, Lee SI, Choi CH, Park KY, Park CH
Ann Thorac Surg 2020 Apr;109(4):e283-e284. Epub 2019 Sep 11 doi: 10.1016/j.athoracsur.2019.07.072. PMID: 31520636
Sagittal alignment of the first metatarsophalangeal joint after arthrodesis for rheumatoid forefoot deformity.
Tanabe A, Majima T, Onodera T, Sawaguchi N, Watanabe T, Kasahara Y, Takahashi D
J Foot Ankle Surg 2013 May-Jun;52(3):343-7. Epub 2013 Feb 20 doi: 10.1053/j.jfas.2012.12.016. PMID: 23433791
Age differences in hopelessness and toe pain in persons with insulin-dependent and non-insulin-dependent diabetes mellitus.
Morewitz S, Javed N, Tata S, Clark J
J Am Podiatr Med Assoc 2010 Nov-Dec;100(6):445-51. doi: 10.7547/1000445. PMID: 21084529
Acute coronary ischemia following centipede envenomation: case report and review of the literature.
Ozsarac M, Karcioglu O, Ayrik C, Somuncu F, Gumrukcu S
Wilderness Environ Med 2004 Summer;15(2):109-12. doi: 10.1580/1080-6032(2004)015[0109:acifce]2.0.co;2. PMID: 15228064

Diagnosis

Pernio-Induced Toe Pain in the Setting of Onychocryptosis: A Case Report.
Logan D, So E, Sundling RA
J Am Podiatr Med Assoc 2020 Jan;110(1):Article7. doi: 10.7547/18-018. PMID: 32073325
A Rare Combination of CYP2C9*3/*3 and VKORC1 1639AA in a Patient Who Had Myxoma and Thromboembolism.
Son KH, Lee SI, Choi CH, Park KY, Park CH
Ann Thorac Surg 2020 Apr;109(4):e283-e284. Epub 2019 Sep 11 doi: 10.1016/j.athoracsur.2019.07.072. PMID: 31520636
Hallucal sesamoiditis manifested on bone scan.
Yang RH, Chu YK
Clin Nucl Med 2013 Dec;38(12):1019-21. doi: 10.1097/RLU.0000000000000283. PMID: 24212448
Acute coronary ischemia following centipede envenomation: case report and review of the literature.
Ozsarac M, Karcioglu O, Ayrik C, Somuncu F, Gumrukcu S
Wilderness Environ Med 2004 Summer;15(2):109-12. doi: 10.1580/1080-6032(2004)015[0109:acifce]2.0.co;2. PMID: 15228064
Great toe pain.
Vilke GM
J Emerg Med 2003 Jan;24(1):59-60. doi: 10.1016/s0736-4679(02)00667-4. PMID: 12554041

Therapy

Unremitting Pain and Fever in a 15-Year-Old Boy With Osteomyelitis.
Cain KS, Shetty AK, Strowd L, Sangueza O, Potisek NM
Pediatrics 2021 Mar;147(3) Epub 2021 Feb 9 doi: 10.1542/peds.2020-012260. PMID: 33563770
Successful Treatment of Covid-19 Associated Cytokine Release Syndrome with Colchicine. A Case Report and Review of Literature.
Mansouri N, Marjani M, Tabarsi P, von Garnier C, Mansouri D
Immunol Invest 2021 Nov;50(8):884-890. Epub 2020 Jul 7 doi: 10.1080/08820139.2020.1789655. PMID: 32633162Free PMC Article
A Rare Combination of CYP2C9*3/*3 and VKORC1 1639AA in a Patient Who Had Myxoma and Thromboembolism.
Son KH, Lee SI, Choi CH, Park KY, Park CH
Ann Thorac Surg 2020 Apr;109(4):e283-e284. Epub 2019 Sep 11 doi: 10.1016/j.athoracsur.2019.07.072. PMID: 31520636
Blue toe syndrome after initiation of low-dose oral anticoagulation.
Rauh G, Spengel FA
Eur J Med Res 1998 Jun 17;3(6):278-80. PMID: 9620888
Toe pain in a hypertensive male.
Layfer LF, Jones JV
IMJ Ill Med J 1982 May;161(5):362-3. PMID: 6124526

Prognosis

Previously unreported X-ray findings associated with distal toe pain in children.
Taniwaki H, Shintani K, Aono M
J Pediatr Orthop B 2024 Jan 1;33(1):53-57. Epub 2023 Feb 8 doi: 10.1097/BPB.0000000000001064. PMID: 36756944
Manual and manipulative therapy compared to night splint for symptomatic hallux abducto valgus: an exploratory randomised clinical trial.
du Plessis M, Zipfel B, Brantingham JW, Parkin-Smith GF, Birdsey P, Globe G, Cassa TK
Foot (Edinb) 2011 Jun;21(2):71-8. Epub 2011 Jan 14 doi: 10.1016/j.foot.2010.11.006. PMID: 21237635
Acute coronary ischemia following centipede envenomation: case report and review of the literature.
Ozsarac M, Karcioglu O, Ayrik C, Somuncu F, Gumrukcu S
Wilderness Environ Med 2004 Summer;15(2):109-12. doi: 10.1580/1080-6032(2004)015[0109:acifce]2.0.co;2. PMID: 15228064
Long-term results of free vascularized second toe joint transfers to finger proximal interphalangeal joints.
Tsubokawa N, Yoshizu T, Maki Y
J Hand Surg Am 2003 May;28(3):443-7. doi: 10.1053/jhsu.2003.50087. PMID: 12772102
Blue toe syndrome after initiation of low-dose oral anticoagulation.
Rauh G, Spengel FA
Eur J Med Res 1998 Jun 17;3(6):278-80. PMID: 9620888

Clinical prediction guides

Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults.
Clarke GR, Thomas MJ, Rathod-Mistry T, Marshall M, Menz HB, Peat G, Roddy E
Musculoskeletal Care 2020 Sep;18(3):383-390. Epub 2020 Apr 20 doi: 10.1002/msc.1472. PMID: 32311212
Quality of Life in Patients With Untreated and Symptomatic Hallux Valgus.
Yamamoto Y, Yamaguchi S, Muramatsu Y, Terakado A, Sasho T, Akagi R, Endo J, Sato Y, Takahashi K
Foot Ankle Int 2016 Nov;37(11):1171-1177. Epub 2016 Jun 25 doi: 10.1177/1071100716655433. PMID: 27344052
A Rare Case of Glomus Tumor of the Great Toe: An Analysis of Behavior at This Rare Site.
Mohindra M, Sambandam B, Gautam VK, Maini L
Foot Ankle Spec 2016 Feb;9(1):83-7. doi: 10.1177/1938640015578517. PMID: 26864831
Are hallux valgus and big toe pain associated with impaired quality of life? A cross-sectional study.
Abhishek A, Roddy E, Zhang W, Doherty M
Osteoarthritis Cartilage 2010 Jul;18(7):923-6. Epub 2010 Apr 22 doi: 10.1016/j.joca.2010.03.011. PMID: 20417286
Nutritional disorders among workers in North China during national turmoil.
Lee BY, Thurmon TF
Ann Nutr Metab 2001;45(4):175-80. doi: 10.1159/000046726. PMID: 11464001

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