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conduct disorder

MedGen UID:
56196
•Concept ID:
C0149654
•
Mental or Behavioral Dysfunction
Synonyms: Conduct Disorder; Conduct Disorders
SNOMED CT: Conduct disorder (430909002)
 
Monarch Initiative: MONDO:0005352

Definition

A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVconduct disorder

Recent clinical studies

Etiology

Modeling the Comorbidity of Cannabis Abuse and Conduct Disorder/Conduct Problems from a Cognitive Neuroscience Perspective.
Blair RJ
J Dual Diagn 2020 Jan-Mar;16(1):3-21. Epub 2019 Oct 14 doi: 10.1080/15504263.2019.1668099. PMID: 31608811
Conduct disorder.
Fairchild G, Hawes DJ, Frick PJ, Copeland WE, Odgers CL, Franke B, Freitag CM, De Brito SA
Nat Rev Dis Primers 2019 Jun 27;5(1):43. doi: 10.1038/s41572-019-0095-y. PMID: 31249310
Conduct Disorder: Recognition and Management.
Lillig M
Am Fam Physician 2018 Nov 15;98(10):584-592. PMID: 30365289
Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits.
Pisano S, Muratori P, Gorga C, Levantini V, Iuliano R, Catone G, Coppola G, Milone A, Masi G
Ital J Pediatr 2017 Sep 20;43(1):84. doi: 10.1186/s13052-017-0404-6. PMID: 28931400Free PMC Article
Juvenile Firesetting.
Peters B, Freeman B
Child Adolesc Psychiatr Clin N Am 2016 Jan;25(1):99-106. Epub 2015 Oct 21 doi: 10.1016/j.chc.2015.08.009. PMID: 26593122

Diagnosis

Conduct disorder.
Nat Rev Dis Primers 2019 Jun 27;5(1):44. doi: 10.1038/s41572-019-0100-5. PMID: 31249311
Conduct disorder.
Fairchild G, Hawes DJ, Frick PJ, Copeland WE, Odgers CL, Franke B, Freitag CM, De Brito SA
Nat Rev Dis Primers 2019 Jun 27;5(1):43. doi: 10.1038/s41572-019-0095-y. PMID: 31249310
Conduct Disorder: Recognition and Management.
Lillig M
Am Fam Physician 2018 Nov 15;98(10):584-592. PMID: 30365289
Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits.
Pisano S, Muratori P, Gorga C, Levantini V, Iuliano R, Catone G, Coppola G, Milone A, Masi G
Ital J Pediatr 2017 Sep 20;43(1):84. doi: 10.1186/s13052-017-0404-6. PMID: 28931400Free PMC Article
The Natural History of Antisocial Personality Disorder.
Black DW
Can J Psychiatry 2015 Jul;60(7):309-14. doi: 10.1177/070674371506000703. PMID: 26175389Free PMC Article

Therapy

Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis.
Haan E, Westmoreland KE, Schellhas L, Sallis HM, Taylor G, Zuccolo L, Munafò MR
Addiction 2022 Oct;117(10):2602-2613. Epub 2022 Apr 6 doi: 10.1111/add.15858. PMID: 35385887Free PMC Article
The Importance of Conduct Disorder in the Treatment of Violence in Schizophrenia: Efficacy of Clozapine Compared With Olanzapine and Haloperidol.
Krakowski M, Tural U, Czobor P
Am J Psychiatry 2021 Mar 1;178(3):266-274. Epub 2021 Jan 21 doi: 10.1176/appi.ajp.2020.20010052. PMID: 33472389
Using antipsychotics for behavioral problems in children.
Shafiq S, Pringsheim T
Expert Opin Pharmacother 2018 Sep;19(13):1475-1488. Epub 2018 Aug 13 doi: 10.1080/14656566.2018.1509069. PMID: 30102079
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 2: antipsychotics and traditional mood stabilizers.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):52-61. doi: 10.1177/070674371506000203. PMID: 25886656Free PMC Article
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article

Prognosis

Conduct Disorder in Immigrant Children and Adolescents: A Nationwide Cohort Study in Sweden.
Osooli M, Ohlsson H, Sundquist J, Sundquist K
Int J Environ Res Public Health 2021 Oct 11;18(20) doi: 10.3390/ijerph182010643. PMID: 34682389Free PMC Article
Infant Iron Deficiency and Iron Supplementation Predict Adolescent Internalizing, Externalizing, and Social Problems.
Doom JR, Richards B, Caballero G, Delva J, Gahagan S, Lozoff B
J Pediatr 2018 Apr;195:199-205.e2. Epub 2018 Feb 1 doi: 10.1016/j.jpeds.2017.12.008. PMID: 29395182Free PMC Article
Preventing Conduct Disorder and Callous Unemotional Traits: Preliminary Results of a School Based Pilot Training Program.
Kyranides MN, Fanti KA, Katsimicha E, Georgiou G
J Abnorm Child Psychol 2018 Feb;46(2):291-303. doi: 10.1007/s10802-017-0273-x. PMID: 28144810
Conduct disorder: long-term outcomes and intervention effectiveness.
Offord DR, Bennett KJ
J Am Acad Child Adolesc Psychiatry 1994 Oct;33(8):1069-78. doi: 10.1097/00004583-199410000-00001. PMID: 7982856
Co-occurrence of conduct disorder and its adult outcomes with depressive and anxiety disorders: a review.
Zoccolillo M
J Am Acad Child Adolesc Psychiatry 1992 May;31(3):547-56. doi: 10.1097/00004583-199205000-00024. PMID: 1592790

Clinical prediction guides

Perpetrators and victims of cyberbullying among youth with conduct disorder.
Baumann S, Bernhard A, Martinelli A, Ackermann K, Herpertz-Dahlmann B, Freitag C, Konrad K, Kohls G
Eur Child Adolesc Psychiatry 2023 Sep;32(9):1643-1653. Epub 2022 Mar 29 doi: 10.1007/s00787-022-01973-0. PMID: 35348888Free PMC Article
Understanding heterogeneity in conduct disorder: A review of psychophysiological studies.
Fanti KA
Neurosci Biobehav Rev 2018 Aug;91:4-20. Epub 2016 Sep 28 doi: 10.1016/j.neubiorev.2016.09.022. PMID: 27693700
Conduct disorder and callous-unemotional traits in youth.
Blair RJ, Leibenluft E, Pine DS
N Engl J Med 2014 Dec 4;371(23):2207-16. doi: 10.1056/NEJMra1315612. PMID: 25470696Free PMC Article
Perspectives on oppositional defiant disorder, conduct disorder, and psychopathic features.
Loeber R, Burke J, Pardini DA
J Child Psychol Psychiatry 2009 Jan;50(1-2):133-42. doi: 10.1111/j.1469-7610.2008.02011.x. PMID: 19220596
Pharmacological aspects of the treatment of conduct disorder in children and adolescents.
Tcheremissine OV, Lieving LM
CNS Drugs 2006;20(7):549-65. doi: 10.2165/00023210-200620070-00002. PMID: 16800715

Recent systematic reviews

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis.
Fellmeth G, Rose-Clarke K, Zhao C, Busert LK, Zheng Y, Massazza A, Sonmez H, Eder B, Blewitt A, Lertgrai W, Orcutt M, Ricci K, Mohamed-Ahmed O, Burns R, Knipe D, Hargreaves S, Hesketh T, Opondo C, Devakumar D
Lancet 2018 Dec 15;392(10164):2567-2582. Epub 2018 Dec 5 doi: 10.1016/S0140-6736(18)32558-3. PMID: 30528471Free PMC Article
Treatment of behavioral and psychological symptoms of dementia: a systematic review.
Preuss UW, Wong JW, Koller G
Psychiatr Pol 2016;50(4):679-715. doi: 10.12740/PP/64477. PMID: 27847922
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 2: antipsychotics and traditional mood stabilizers.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):52-61. doi: 10.1177/070674371506000203. PMID: 25886656Free PMC Article
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article

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