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Fatty streak

MedGen UID:
569155
•Concept ID:
C0333484
•
Finding
Synonyms: Fatty dots; Fatty streaks; Lipid streaks; Sudanophilic lesion; Yellow dots; Yellow streaks
SNOMED CT: Fatty streaks (53151000); Lipid streaks (53151000); Yellow streaks (53151000); Yellow dots (53151000); Fatty dots (53151000)
 
HPO: HP:0031011

Definition

Yellow-colored streaks, patches, or spots on the intimal surface of arteries. Fatty streaks stain red with Sudan III or Sudan IV. [from HPO]

Professional guidelines

PubMed

Recent Advances in Understanding the Pathogenesis of Cardiovascular Diseases and Development of Treatment Modalities.
Mittal R, Jhaveri VM, Kay SS, Greer A, Sutherland KJ, McMurry HS, Lin N, Mittal J, Malhotra AK, Patel AP
Cardiovasc Hematol Disord Drug Targets 2019;19(1):19-32. doi: 10.2174/1871529X18666180508111353. PMID: 29737266
A review of the peri-operative risk stratification assessment tools used for the prediction of cardiovascular complications in non-cardiac surgery.
Magapu P, Haskard D, Fisher M
Perfusion 2016 Jul;31(5):358-65. Epub 2015 Nov 12 doi: 10.1177/0267659115615207. PMID: 26567135
Hypertension treatment and prevention of new atherosclerotic plaque formation.
Rafflenbeul W
Drugs 1994;48 Suppl 1:11-5. doi: 10.2165/00003495-199400481-00005. PMID: 7533701

Recent clinical studies

Therapy

Keep recycling going: New approaches to reduce LDL-C.
Klein-Szanto AJP, Bassi DE
Biochem Pharmacol 2019 Jun;164:336-341. Epub 2019 Apr 4 doi: 10.1016/j.bcp.2019.04.003. PMID: 30953636
Therapeutic Potential of Modulating microRNAs in Atherosclerotic Vascular Disease.
Araldi E, Chamorro-Jorganes A, van Solingen C, Fernandez-Hernando C, Suarez Y
Curr Vasc Pharmacol 2015;13(3):291-304. PMID: 26156264
CRP and the risk of atherosclerotic events.
Calabrò P, Golia E, Yeh ET
Semin Immunopathol 2009 Jun;31(1):79-94. Epub 2009 May 5 doi: 10.1007/s00281-009-0149-4. PMID: 19415283
PPARgamma and atherosclerosis.
Staels B
Curr Med Res Opin 2005;21 Suppl 1:S13-20. doi: 10.1185/030079905X36440. PMID: 15811195
Lipid lowering improves endothelial functions.
Libby P, Aikawa M, Kinlay S, Selwyn A, Ganz P
Int J Cardiol 2000 Jun 30;74 Suppl 1:S3-S10. doi: 10.1016/s0167-5273(99)00105-9. PMID: 10856767

Prognosis

Inflammatory Biomarkers for Cardiovascular Risk Stratification in Familial Hypercholesterolemia.
Bahrami A, Liberale L, Reiner Ž, Carbone F, Montecucco F, Sahebkar A
Rev Physiol Biochem Pharmacol 2020;177:25-52. doi: 10.1007/112_2020_26. PMID: 32691159
Inflammation, atherosclerosis, and psoriasis.
Siegel D, Devaraj S, Mitra A, Raychaudhuri SP, Raychaudhuri SK, Jialal I
Clin Rev Allergy Immunol 2013 Apr;44(2):194-204. doi: 10.1007/s12016-012-8308-0. PMID: 22359071
CRP and the risk of atherosclerotic events.
Calabrò P, Golia E, Yeh ET
Semin Immunopathol 2009 Jun;31(1):79-94. Epub 2009 May 5 doi: 10.1007/s00281-009-0149-4. PMID: 19415283
C-reactive protein: risk marker or mediator in atherothrombosis?
Jialal I, Devaraj S, Venugopal SK
Hypertension 2004 Jul;44(1):6-11. Epub 2004 May 17 doi: 10.1161/01.HYP.0000130484.20501.df. PMID: 15148294
Atherosclerosis and inflammation.
Farmer JA, Torre-Amione G
Curr Atheroscler Rep 2002 Mar;4(2):92-8. doi: 10.1007/s11883-002-0031-5. PMID: 11822971

Clinical prediction guides

Inflammatory Biomarkers for Cardiovascular Risk Stratification in Familial Hypercholesterolemia.
Bahrami A, Liberale L, Reiner Ž, Carbone F, Montecucco F, Sahebkar A
Rev Physiol Biochem Pharmacol 2020;177:25-52. doi: 10.1007/112_2020_26. PMID: 32691159
Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease.
Maguire EM, Pearce SWA, Xiao Q
Vascul Pharmacol 2019 Jan;112:54-71. Epub 2018 Aug 14 doi: 10.1016/j.vph.2018.08.002. PMID: 30115528
Inflammation, atherosclerosis, and psoriasis.
Siegel D, Devaraj S, Mitra A, Raychaudhuri SP, Raychaudhuri SK, Jialal I
Clin Rev Allergy Immunol 2013 Apr;44(2):194-204. doi: 10.1007/s12016-012-8308-0. PMID: 22359071
Macrophage differentiation to foam cells.
Shashkin P, Dragulev B, Ley K
Curr Pharm Des 2005;11(23):3061-72. doi: 10.2174/1381612054865064. PMID: 16178764
Atherosclerosis and inflammation.
Farmer JA, Torre-Amione G
Curr Atheroscler Rep 2002 Mar;4(2):92-8. doi: 10.1007/s11883-002-0031-5. PMID: 11822971

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