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Iron deficiency without anemia

MedGen UID:
574088
Concept ID:
C0340950
Disease or Syndrome
Synonyms: Iron Deficiency without Anemia; Non-Anemic Iron Deficiency; Sideropenia
SNOMED CT: Sideropenia (234340006); Iron deficiency without anemia (234340006)

Definition

Subnormal concentrations of iron resulting from low iron intake, inefficient iron absorption in the gastrointestinal tract, or increased iron loss; occurring in the absence of anemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIron deficiency without anemia

Professional guidelines

PubMed

DeLoughery TG, Jackson CS, Ko CW, Rockey DC
Clin Gastroenterol Hepatol 2024 Aug;22(8):1575-1583. Epub 2024 Jun 12 doi: 10.1016/j.cgh.2024.03.046. PMID: 38864796
Elmore C, Ellis J
J Midwifery Womens Health 2022 May;67(3):321-331. Epub 2022 Jun 1 doi: 10.1111/jmwh.13370. PMID: 35642737
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Recent clinical studies

Etiology

Elmore C, Ellis J
J Midwifery Womens Health 2022 May;67(3):321-331. Epub 2022 Jun 1 doi: 10.1111/jmwh.13370. PMID: 35642737
Alexandre L, Chan SSM
Curr Opin Gastroenterol 2021 Mar 1;37(2):121-127. doi: 10.1097/MOG.0000000000000702. PMID: 33315792
Musallam KM, Taher AT
Curr Med Res Opin 2018 Jan;34(1):81-93. Epub 2017 Nov 3 doi: 10.1080/03007995.2017.1394833. PMID: 29050512
Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics
Pediatrics 2010 Nov;126(5):1040-50. Epub 2010 Oct 5 doi: 10.1542/peds.2010-2576. PMID: 20923825
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Diagnosis

Lewkowitz AK, Tuuli MG
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):223-228. doi: 10.1182/hematology.2023000474. PMID: 38066889Free PMC Article
Elmore C, Ellis J
J Midwifery Womens Health 2022 May;67(3):321-331. Epub 2022 Jun 1 doi: 10.1111/jmwh.13370. PMID: 35642737
Alexandre L, Chan SSM
Curr Opin Gastroenterol 2021 Mar 1;37(2):121-127. doi: 10.1097/MOG.0000000000000702. PMID: 33315792
Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics
Pediatrics 2010 Nov;126(5):1040-50. Epub 2010 Oct 5 doi: 10.1542/peds.2010-2576. PMID: 20923825
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Therapy

Lewkowitz AK, Tuuli MG
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):223-228. doi: 10.1182/hematology.2023000474. PMID: 38066889Free PMC Article
Elmore C, Ellis J
J Midwifery Womens Health 2022 May;67(3):321-331. Epub 2022 Jun 1 doi: 10.1111/jmwh.13370. PMID: 35642737
Musallam KM, Taher AT
Curr Med Res Opin 2018 Jan;34(1):81-93. Epub 2017 Nov 3 doi: 10.1080/03007995.2017.1394833. PMID: 29050512
Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics
Pediatrics 2010 Nov;126(5):1040-50. Epub 2010 Oct 5 doi: 10.1542/peds.2010-2576. PMID: 20923825
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Prognosis

Zia A, Stanek J, Christian-Rancy M, Savelli S, O'Brien SH
Am J Hematol 2022 Jan 1;97(1):60-67. Epub 2021 Nov 8 doi: 10.1002/ajh.26389. PMID: 34710246
Alexandre L, Chan SSM
Curr Opin Gastroenterol 2021 Mar 1;37(2):121-127. doi: 10.1097/MOG.0000000000000702. PMID: 33315792
Halfvarson J, Cummings F, Grip O, Savoye G
World J Gastroenterol 2018 Mar 14;24(10):1063-1071. doi: 10.3748/wjg.v24.i10.1063. PMID: 29563751Free PMC Article
Parks RB, Hetzel SJ, Brooks MA
Med Sci Sports Exerc 2017 Aug;49(8):1711-1715. doi: 10.1249/MSS.0000000000001259. PMID: 28277407
Isanaka S, Mugusi F, Urassa W, Willett WC, Bosch RJ, Villamor E, Spiegelman D, Duggan C, Fawzi WW
J Nutr 2012 Feb;142(2):350-7. Epub 2011 Dec 21 doi: 10.3945/jn.111.144287. PMID: 22190024Free PMC Article

Clinical prediction guides

Zia A, Stanek J, Christian-Rancy M, Savelli S, O'Brien SH
Am J Hematol 2022 Jan 1;97(1):60-67. Epub 2021 Nov 8 doi: 10.1002/ajh.26389. PMID: 34710246
Alexandre L, Chan SSM
Curr Opin Gastroenterol 2021 Mar 1;37(2):121-127. doi: 10.1097/MOG.0000000000000702. PMID: 33315792
Froessler B, Gajic T, Dekker G, Hodyl NA
Arch Gynecol Obstet 2018 Jul;298(1):75-82. Epub 2018 May 8 doi: 10.1007/s00404-018-4782-9. PMID: 29740690Free PMC Article
Musallam KM, Taher AT
Curr Med Res Opin 2018 Jan;34(1):81-93. Epub 2017 Nov 3 doi: 10.1080/03007995.2017.1394833. PMID: 29050512
Isanaka S, Mugusi F, Urassa W, Willett WC, Bosch RJ, Villamor E, Spiegelman D, Duggan C, Fawzi WW
J Nutr 2012 Feb;142(2):350-7. Epub 2011 Dec 21 doi: 10.3945/jn.111.144287. PMID: 22190024Free PMC Article

Recent systematic reviews

Haas JD, Brownlie T 4th
J Nutr 2001 Feb;131(2S-2):676S-688S; discussion 688S-690S. doi: 10.1093/jn/131.2.676S. PMID: 11160598

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