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Drug-induced anaphylaxis

MedGen UID:
576123
•Concept ID:
C0344168
•
Disease or Syndrome
Synonym: Drug induced anaphylaxis
SNOMED CT: Drug-induced anaphylaxis (241937000)
 
HPO: HP:0410149

Definition

A form of anaphylaxis that is triggered by intake of drugs or medications. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDrug-induced anaphylaxis

Professional guidelines

PubMed

Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: General Concepts.
Broyles AD, Banerji A, Castells M
J Allergy Clin Immunol Pract 2020 Oct;8(9S):S3-S15. Epub 2020 Aug 11 doi: 10.1016/j.jaip.2020.08.002. PMID: 32791249
Diagnosis and management of drug-induced anaphylaxis in children: An EAACI position paper.
Atanaskovic-Markovic M, Gomes E, Cernadas JR, du Toit G, Kidon M, Kuyucu S, Mori F, Ponvert C, Terreehorst I, Caubet JC
Pediatr Allergy Immunol 2019 May;30(3):269-276. doi: 10.1111/pai.13034. PMID: 30734362
Recognition and Management of Anaphylaxis in Older Adults.
Plagova A, Nykamp D
Consult Pharm 2017 Jul 1;32(7):398-405. doi: 10.4140/TCP.n.2017.398. PMID: 28701251

Recent clinical studies

Etiology

Hypersensitivity reactions to chemotherapy: an EAACI Position Paper.
Pagani M, Bavbek S, Alvarez-Cuesta E, Berna Dursun A, Bonadonna P, Castells M, Cernadas J, Chiriac A, Sahar H, Madrigal-Burgaleta R, Sanchez Sanchez S
Allergy 2022 Feb;77(2):388-403. Epub 2021 Oct 26 doi: 10.1111/all.15113. PMID: 34587281
Mechanisms of human drug-induced anaphylaxis.
Bruhns P, Chollet-Martin S
J Allergy Clin Immunol 2021 Apr;147(4):1133-1142. doi: 10.1016/j.jaci.2021.02.013. PMID: 33832695
Cross-reactivity in β-Lactam Allergy.
Zagursky RJ, Pichichero ME
J Allergy Clin Immunol Pract 2018 Jan-Feb;6(1):72-81.e1. Epub 2017 Oct 7 doi: 10.1016/j.jaip.2017.08.027. PMID: 29017833
Mastocytosis and Anaphylaxis.
Schuch A, Brockow K
Immunol Allergy Clin North Am 2017 Feb;37(1):153-164. Epub 2016 Oct 28 doi: 10.1016/j.iac.2016.08.017. PMID: 27886904
Anaphylaxis to drugs.
Kuruvilla M, Khan DA
Immunol Allergy Clin North Am 2015 May;35(2):303-19. Epub 2015 Mar 3 doi: 10.1016/j.iac.2015.01.008. PMID: 25841553

Diagnosis

Drug-induced Anaphylaxis.
Labella M, de Santa María RS, Bogas G, Salas M, Fernández TD, Mayorga C, Torres MJ, Doña I
Curr Pharm Des 2023;29(3):196-208. doi: 10.2174/1381612829666221024154951. PMID: 36284381
Hypersensitivity reactions to chemotherapy: an EAACI Position Paper.
Pagani M, Bavbek S, Alvarez-Cuesta E, Berna Dursun A, Bonadonna P, Castells M, Cernadas J, Chiriac A, Sahar H, Madrigal-Burgaleta R, Sanchez Sanchez S
Allergy 2022 Feb;77(2):388-403. Epub 2021 Oct 26 doi: 10.1111/all.15113. PMID: 34587281
Drug-induced anaphylaxis in children.
Cardinale F, Amato D, Mastrototaro MF, Caffarelli C, Crisafulli G, Franceschini F, Liotti L, Caimmi S, Bottau P, Saretta F, Mori F, Bernardini R
Acta Biomed 2019 Jan 30;90(3-S):30-35. doi: 10.23750/abm.v90i3-S.8172. PMID: 30830059Free PMC Article
Drug-Induced Anaphylaxis.
Aun MV, Kalil J, Giavina-Bianchi P
Immunol Allergy Clin North Am 2017 Nov;37(4):629-641. Epub 2017 Aug 9 doi: 10.1016/j.iac.2017.06.002. PMID: 28965631
Anaphylaxis to drugs.
Kuruvilla M, Khan DA
Immunol Allergy Clin North Am 2015 May;35(2):303-19. Epub 2015 Mar 3 doi: 10.1016/j.iac.2015.01.008. PMID: 25841553

Therapy

Drug Allergy in Women.
Lee EY, Copaescu AM, Trubiano JA, Phillips EJ, Wolfson AR, Ramsey A
J Allergy Clin Immunol Pract 2023 Dec;11(12):3615-3623. Epub 2023 Oct 5 doi: 10.1016/j.jaip.2023.09.031. PMID: 37805007
Hypersensitivity reactions to chemotherapy: an EAACI Position Paper.
Pagani M, Bavbek S, Alvarez-Cuesta E, Berna Dursun A, Bonadonna P, Castells M, Cernadas J, Chiriac A, Sahar H, Madrigal-Burgaleta R, Sanchez Sanchez S
Allergy 2022 Feb;77(2):388-403. Epub 2021 Oct 26 doi: 10.1111/all.15113. PMID: 34587281
Drug-induced anaphylaxis: is it an epidemic?
Giavina-Bianchi P, Aun MV, Kalil J
Curr Opin Allergy Clin Immunol 2018 Feb;18(1):59-65. doi: 10.1097/ACI.0000000000000411. PMID: 29135486
Cross-reactivity in β-Lactam Allergy.
Zagursky RJ, Pichichero ME
J Allergy Clin Immunol Pract 2018 Jan-Feb;6(1):72-81.e1. Epub 2017 Oct 7 doi: 10.1016/j.jaip.2017.08.027. PMID: 29017833
Drug-Induced Anaphylaxis.
Aun MV, Kalil J, Giavina-Bianchi P
Immunol Allergy Clin North Am 2017 Nov;37(4):629-641. Epub 2017 Aug 9 doi: 10.1016/j.iac.2017.06.002. PMID: 28965631

Prognosis

Drug-Induced Anaphylaxis: An Update on Epidemiology and Risk Factors.
Regateiro FS, Marques ML, Gomes ER
Int Arch Allergy Immunol 2020;181(7):481-487. Epub 2020 May 12 doi: 10.1159/000507445. PMID: 32396909
Drug-induced anaphylaxis: is it an epidemic?
Giavina-Bianchi P, Aun MV, Kalil J
Curr Opin Allergy Clin Immunol 2018 Feb;18(1):59-65. doi: 10.1097/ACI.0000000000000411. PMID: 29135486
Cross-reactivity in β-Lactam Allergy.
Zagursky RJ, Pichichero ME
J Allergy Clin Immunol Pract 2018 Jan-Feb;6(1):72-81.e1. Epub 2017 Oct 7 doi: 10.1016/j.jaip.2017.08.027. PMID: 29017833
Immediate-type hypersensitivity drug reactions.
Stone SF, Phillips EJ, Wiese MD, Heddle RJ, Brown SG
Br J Clin Pharmacol 2014 Jul;78(1):1-13. doi: 10.1111/bcp.12297. PMID: 24286446Free PMC Article
Preventing and managing drug-induced anaphylaxis.
Drain KL, Volcheck GW
Drug Saf 2001;24(11):843-53. doi: 10.2165/00002018-200124110-00005. PMID: 11665871

Clinical prediction guides

Drug-Induced Anaphylaxis Documented in Electronic Health Records.
Dhopeshwarkar N, Sheikh A, Doan R, Topaz M, Bates DW, Blumenthal KG, Zhou L
J Allergy Clin Immunol Pract 2019 Jan;7(1):103-111. Epub 2018 Jun 30 doi: 10.1016/j.jaip.2018.06.010. PMID: 29969686Free PMC Article
Cross-reactivity in β-Lactam Allergy.
Zagursky RJ, Pichichero ME
J Allergy Clin Immunol Pract 2018 Jan-Feb;6(1):72-81.e1. Epub 2017 Oct 7 doi: 10.1016/j.jaip.2017.08.027. PMID: 29017833
Clindamycin-induced hypersensitivity reaction.
Bulloch MN, Baccas JT, Arnold S
Infection 2016 Jun;44(3):357-9. Epub 2015 Jul 28 doi: 10.1007/s15010-015-0826-2. PMID: 26216470
Immediate-type hypersensitivity drug reactions.
Stone SF, Phillips EJ, Wiese MD, Heddle RJ, Brown SG
Br J Clin Pharmacol 2014 Jul;78(1):1-13. doi: 10.1111/bcp.12297. PMID: 24286446Free PMC Article
Preventing and managing drug-induced anaphylaxis.
Drain KL, Volcheck GW
Drug Saf 2001;24(11):843-53. doi: 10.2165/00002018-200124110-00005. PMID: 11665871

Recent systematic reviews

Health-Related Quality of Life and Mental Health in Drug Hypersensitivity Reactions and Drug-Induced Anaphylaxis: A Systematic Review and Meta-Analysis.
Martini M, Di Taranto M, Höfer V, Worm M, Bilò MB
J Allergy Clin Immunol Pract 2023 Jun;11(6):1876-1890. Epub 2023 Mar 21 doi: 10.1016/j.jaip.2023.03.012. PMID: 36958518
Economic burden of drug-induced anaphylaxis: what can we do better?
Cardoso B, Moscoso T, Morais-Almeida M, Demoly P, Tanno LK
Curr Opin Allergy Clin Immunol 2022 Aug 1;22(4):234-241. doi: 10.1097/ACI.0000000000000836. PMID: 35852897
Global patterns of drug allergy-induced fatalities: a wake-up call to prevent avoidable deaths.
Tanno LK, Gauthier A, Allichon S, Demoly P
Curr Opin Allergy Clin Immunol 2022 Aug 1;22(4):215-220. doi: 10.1097/ACI.0000000000000835. PMID: 35852895
Drug-induced anaphylaxis: seven-year single-center survey.
Mota I, Gaspar Â, Benito-Garcia F, Correia M, Chambel M, Morais-Almeida M
Eur Ann Allergy Clin Immunol 2018 Sep;50(5):211-216. Epub 2018 Jul 20 doi: 10.23822/EurAnnACI.1764-1489.66. PMID: 30028111

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