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Anaphylactic shock

MedGen UID:
1373755
Concept ID:
C4316895
Pathologic Function
Synonym: Anaphylaxis
SNOMED CT: Anaphylactic shock (735173007); Shock due to anaphylaxis (735173007)
 
HPO: HP:0100845
Monarch Initiative: MONDO:0100053

Definition

An acute hypersensitivity reaction due to exposure to a previously encountered antigen. [from HPO]

Conditions with this feature

Combined immunodeficiency due to DOCK8 deficiency
MedGen UID:
1648410
Concept ID:
C4722305
Disease or Syndrome
Hyper-IgE syndrome-2 with recurrent infections (HIES2) is an autosomal recessive immunologic disorder characterized by recurrent staphylococcal infections of the skin and respiratory tract, eczema, elevated serum immunoglobulin E, and hypereosinophilia. It is distinguished from autosomal dominant HIES1 (147060) by the lack of connective tissue and skeletal involvement (Renner et al., 2004). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see 147060. See also TYK2 deficiency (611521), a clinically distinct disease entity that includes characteristic features of both autosomal recessive HIES2 and mendelian susceptibility to mycobacterial disease (MSMD; 209950) (Minegishi et al., 2006).

Professional guidelines

PubMed

McHugh K, Repanshek Z
Immunol Allergy Clin North Am 2023 Aug;43(3):453-466. doi: 10.1016/j.iac.2022.10.002. PMID: 37394252
McHugh K, Repanshek Z
Emerg Med Clin North Am 2022 Feb;40(1):19-32. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.004. PMID: 34782088
Krishnaswamy G
Crit Care Med 2021 May 1;49(5):838-857. doi: 10.1097/CCM.0000000000004893. PMID: 33653974

Recent clinical studies

Etiology

McHugh K, Repanshek Z
Emerg Med Clin North Am 2022 Feb;40(1):19-32. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.004. PMID: 34782088
Krishnaswamy G
Crit Care Med 2021 May 1;49(5):838-857. doi: 10.1097/CCM.0000000000004893. PMID: 33653974
Carlson G, Coop C
Ann Allergy Asthma Immunol 2019 Oct;123(4):359-365. Epub 2019 Jul 31 doi: 10.1016/j.anai.2019.07.022. PMID: 31376490
Chinuki Y, Morita E
Allergol Int 2019 Jul;68(3):296-300. Epub 2019 Apr 30 doi: 10.1016/j.alit.2019.04.001. PMID: 31053502
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Diagnosis

Krishnaswamy G
Crit Care Med 2021 May 1;49(5):838-857. doi: 10.1097/CCM.0000000000004893. PMID: 33653974
Poncet P, Sénéchal H, Charpin D
Expert Rev Clin Immunol 2020 Jun;16(6):561-578. doi: 10.1080/1744666X.2020.1774366. PMID: 32691654
Carlson G, Coop C
Ann Allergy Asthma Immunol 2019 Oct;123(4):359-365. Epub 2019 Jul 31 doi: 10.1016/j.anai.2019.07.022. PMID: 31376490
Krčmová I, Novosad J
Vnitr Lek 2019 Winter;65(2):149-156. PMID: 30909706
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Therapy

McHugh K, Repanshek Z
Immunol Allergy Clin North Am 2023 Aug;43(3):453-466. doi: 10.1016/j.iac.2022.10.002. PMID: 37394252
McHugh K, Repanshek Z
Emerg Med Clin North Am 2022 Feb;40(1):19-32. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.004. PMID: 34782088
Krishnaswamy G
Crit Care Med 2021 May 1;49(5):838-857. doi: 10.1097/CCM.0000000000004893. PMID: 33653974
Yiannakopoulou E
Pharmacology 2015;95(1-2):65-9. Epub 2015 Jan 21 doi: 10.1159/000370245. PMID: 25613637
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Prognosis

McHugh K, Repanshek Z
Immunol Allergy Clin North Am 2023 Aug;43(3):453-466. doi: 10.1016/j.iac.2022.10.002. PMID: 37394252
Buttgereit F, Aelion J, Rojkovich B, Zubrzycka-Sienkiewicz A, Chen S, Yang Y, Arikan D, D'Cunha R, Pang Y, Kupper H, Radstake T, Amital H
Arthritis Rheumatol 2023 Jun;75(6):879-889. Epub 2023 Apr 2 doi: 10.1002/art.42415. PMID: 36512671
McHugh K, Repanshek Z
Emerg Med Clin North Am 2022 Feb;40(1):19-32. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.004. PMID: 34782088
Chinuki Y, Morita E
Allergol Int 2019 Jul;68(3):296-300. Epub 2019 Apr 30 doi: 10.1016/j.alit.2019.04.001. PMID: 31053502
Vuitton DA
Clin Rev Allergy Immunol 2004 Apr;26(2):93-104. doi: 10.1007/s12016-004-0004-2. PMID: 15146106

Clinical prediction guides

McHugh K, Repanshek Z
Immunol Allergy Clin North Am 2023 Aug;43(3):453-466. doi: 10.1016/j.iac.2022.10.002. PMID: 37394252
Buttgereit F, Aelion J, Rojkovich B, Zubrzycka-Sienkiewicz A, Chen S, Yang Y, Arikan D, D'Cunha R, Pang Y, Kupper H, Radstake T, Amital H
Arthritis Rheumatol 2023 Jun;75(6):879-889. Epub 2023 Apr 2 doi: 10.1002/art.42415. PMID: 36512671
McHugh K, Repanshek Z
Emerg Med Clin North Am 2022 Feb;40(1):19-32. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.004. PMID: 34782088
Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC
Nat Rev Dis Primers 2018 Jan 4;4:17098. doi: 10.1038/nrdp.2017.98. PMID: 29300005
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Recent systematic reviews

Majsiak E, Choina M, Knyziak-Mędrzycka I, Bierła JB, Janeczek K, Wykrota J, Cukrowska B
Nutrients 2023 Feb 16;15(4) doi: 10.3390/nu15040995. PMID: 36839352Free PMC Article
Krishnaswamy G
Crit Care Med 2021 May 1;49(5):838-857. doi: 10.1097/CCM.0000000000004893. PMID: 33653974
Arcangeli G, Traversini V, Tomasini E, Baldassarre A, Lecca LI, Galea RP, Mucci N
Int J Environ Res Public Health 2020 Jul 8;17(14) doi: 10.3390/ijerph17144921. PMID: 32650469Free PMC Article
Sun KJ, He JT, Huang HY, Xue Y, Xie XL, Wang Q
Forensic Sci Med Pathol 2018 Jun;14(2):209-215. Epub 2018 Apr 21 doi: 10.1007/s12024-018-9980-z. PMID: 29679215
Vermeij JD, Westendorp WF, Dippel DW, van de Beek D, Nederkoorn PJ
Cochrane Database Syst Rev 2018 Jan 22;1(1):CD008530. doi: 10.1002/14651858.CD008530.pub3. PMID: 29355906Free PMC Article

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