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Labyrinthitis

MedGen UID:
5991
•Concept ID:
C0022893
•
Disease or Syndrome
Synonyms: Labyrinthitides; Otitis Interna
SNOMED CT: Labyrinthitis (23919004)
 
Monarch Initiative: MONDO:0002008

Definition

Inflammation of the anatomical structures of the inner ear secondary to an infectious process. Symptoms include severe vertigo, nausea, vomiting, anxiety, and pain. Viral etiology is most common, and recent history of an upper respiratory infection is common. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLabyrinthitis

Professional guidelines

PubMed

Vertigo and dizziness in childhood - update on diagnosis and treatment.
Jahn K, Langhagen T, Schroeder AS, Heinen F
Neuropediatrics 2011 Aug;42(4):129-34. Epub 2011 Jul 15 doi: 10.1055/s-0031-1283158. PMID: 21766267
Treatment of vertigo.
Swartz R, Longwell P
Am Fam Physician 2005 Mar 15;71(6):1115-22. PMID: 15791890
Labyrinthitis; a physiologic approach to its treatment.
MILLER TR
Eye Ear Nose Throat Mon 1958 Sep;37(9):601-3. PMID: 13574199

Recent clinical studies

Etiology

Balance testing: does it make a difference?
Watts E, Lindley K, Irving R, Dalton L
J Laryngol Otol 2023 May;137(5):506-514. Epub 2022 Aug 23 doi: 10.1017/S0022215122001967. PMID: 35995754
Simultaneous Late, Late-Onset Group B Streptococcal Meningitis in Identical Twins.
Sherman G, Lamb GS, Platt CD, Wessels MR, Chochua S, Nakamura MM
Clin Pediatr (Phila) 2023 Feb;62(2):96-99. Epub 2022 Jul 26 doi: 10.1177/00099228221113630. PMID: 35883267Free PMC Article
Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Contemporary surgical issues in paediatric cochlear implantation.
Wasson JD, Briggs RJ
Int J Audiol 2016;55 Suppl 2:S77-87. Epub 2016 Jun 7 doi: 10.1080/14992027.2016.1184765. PMID: 27266370
Mastoidectomy in the elderly.
Migirov L, Weissburd S, Wolf M
ORL J Otorhinolaryngol Relat Spec 2010;72(2):80-3. Epub 2010 May 1 doi: 10.1159/000296137. PMID: 20431317

Diagnosis

Dizziness demystified.
Welgampola MS, Young AS, Pogson JM, Bradshaw AP, Halmagyi GM
Pract Neurol 2019 Dec;19(6):492-501. Epub 2019 Jul 20 doi: 10.1136/practneurol-2019-002199. PMID: 31326945
Infections of the Ear.
Szmuilowicz J, Young R
Emerg Med Clin North Am 2019 Feb;37(1):1-9. doi: 10.1016/j.emc.2018.09.001. PMID: 30454772
Dizziness.
Whitman GT
Am J Med 2018 Dec;131(12):1431-1437. Epub 2018 Jun 1 doi: 10.1016/j.amjmed.2018.05.014. PMID: 29859806
An approach to vertigo in general practice.
Dommaraju S, Perera E
Aust Fam Physician 2016 Apr;45(4):190-4. PMID: 27052132
Positional dizziness.
Fife TD
Continuum (Minneap Minn) 2012 Oct;18(5 Neuro-otology):1060-85. doi: 10.1212/01.CON.0000418376.80099.24. PMID: 23042060

Therapy

Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Contemporary surgical issues in paediatric cochlear implantation.
Wasson JD, Briggs RJ
Int J Audiol 2016;55 Suppl 2:S77-87. Epub 2016 Jun 7 doi: 10.1080/14992027.2016.1184765. PMID: 27266370
Aminoglycoside ototoxicity in the human.
Fee WE Jr
Laryngoscope 1980 Oct;90(10 Pt 2 Suppl 24):1-19. doi: 10.1288/00005537-198010001-00001. PMID: 7432055
Tuberculous otitis media.
Lucente FE, Tobias GW, Parisier SC, Som PM
Laryngoscope 1978 Jul;88(7 Pt 1):1107-16. doi: 10.1002/lary.1978.88.7.1107. PMID: 672345
Pathophysiology of endolymphatic hydrops.
Schuknecht HF
Arch Otorhinolaryngol 1976 Sep 16;212(4):253-62. doi: 10.1007/BF00453673. PMID: 1086664

Prognosis

Non-Syndromic Sensorineural Hearing Loss in Children.
Robson CD, Lewis M, D'Arco F
Neuroimaging Clin N Am 2023 Nov;33(4):531-542. Epub 2023 Jul 11 doi: 10.1016/j.nic.2023.05.005. PMID: 37741656
Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Positional dizziness.
Fife TD
Continuum (Minneap Minn) 2012 Oct;18(5 Neuro-otology):1060-85. doi: 10.1212/01.CON.0000418376.80099.24. PMID: 23042060
Mastoidectomy in the elderly.
Migirov L, Weissburd S, Wolf M
ORL J Otorhinolaryngol Relat Spec 2010;72(2):80-3. Epub 2010 May 1 doi: 10.1159/000296137. PMID: 20431317
Labyrinthitis ossificans.
Suga F, Lindsay JR
Ann Otol Rhinol Laryngol 1977 Jan-Feb;86(1 Pt 1):17-29. doi: 10.1177/000348947708600105. PMID: 402099

Clinical prediction guides

Hearing Preservation After Penetrating Cochlear Injury.
Tarasidis GS, Wiggins RH, Gurgel RK
Ann Otol Rhinol Laryngol 2017 Feb;126(2):163-165. Epub 2016 Nov 19 doi: 10.1177/0003489416676186. PMID: 27866146
Benign positional vertigo: prognostic factors.
Del Rio M, Arriaga MA
Otolaryngol Head Neck Surg 2004 Apr;130(4):426-9. doi: 10.1016/j.otohns.2003.12.015. PMID: 15100638
Significance of spiral ligament fibrocytes with cochlear inflammation.
Ichimiya I, Yoshida K, Hirano T, Suzuki M, Mogi G
Int J Pediatr Otorhinolaryngol 2000 Nov 30;56(1):45-51. doi: 10.1016/s0165-5876(00)00408-0. PMID: 11074115
Acute Streptococcus pneumoniae meningogenic labyrinthitis. An experimental guinea pig model and literature review.
Blank AL, Davis GL, VanDeWater TR, Ruben RJ
Arch Otolaryngol Head Neck Surg 1994 Dec;120(12):1342-6. doi: 10.1001/archotol.1994.01880360040008. PMID: 7980899
Histological considerations in implant patients.
Nadol JB Jr
Arch Otolaryngol 1984 Mar;110(3):160-3. doi: 10.1001/archotol.1984.00800290024005. PMID: 6546683

Recent systematic reviews

Plectranthus Species with Anti-Inflammatory and Analgesic Potential: A Systematic Review on Ethnobotanical and Pharmacological Findings.
Barbosa MO, Wilairatana P, Leite GML, Delmondes GA, Silva LYSD, Júnior SCA, Dantas LBR, Bezerra DS, Beltrão ICSL, Dias DQ, Ribeiro-Filho J, Felipe CFB, Coutinho HDM, Menezes IRA, Kerntopf Mendonça MR
Molecules 2023 Jul 26;28(15) doi: 10.3390/molecules28155653. PMID: 37570622Free PMC Article
Aetiology of Ludwig van Beethoven's hearing impairment: hypotheses over the past 100 years - A systematic review.
Thomas JP, Dazert S, Prescher A, Voelter C
Eur Arch Otorhinolaryngol 2021 Aug;278(8):2703-2712. Epub 2020 Nov 23 doi: 10.1007/s00405-020-06467-w. PMID: 33230590Free PMC Article
The Differential Diagnosis of Vertigo in Children: A Systematic Review of 2726 Cases.
Davitt M, Delvecchio MT, Aronoff SC
Pediatr Emerg Care 2020 Aug;36(8):368-371. doi: 10.1097/PEC.0000000000001281. PMID: 29095392
Cochlear implantation versus auditory brainstem implantation in bilateral total deafness after head trauma: personal experience and review of the literature.
Medina M, Di Lella F, Di Trapani G, Prasad SC, Bacciu A, Aristegui M, Russo A, Sanna M
Otol Neurotol 2014 Feb;35(2):260-70. doi: 10.1097/MAO.0000000000000235. PMID: 24448286
Antibiotic prophylaxis in clean and clean-contaminated ear surgery.
Verschuur HP, de Wever WW, van Benthem PP
Cochrane Database Syst Rev 2004;2004(3):CD003996. doi: 10.1002/14651858.CD003996.pub2. PMID: 15266512Free PMC Article

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