U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Labyrinthitis

MedGen UID:
5991
•Concept ID:
C0022893
•
Disease or Syndrome
Synonyms: Labyrinthitides; Otitis Interna
SNOMED CT: Labyrinthitis (23919004)
 
Monarch Initiative: MONDO:0002008

Definition

Inflammation of the anatomical structures of the inner ear secondary to an infectious process. Symptoms include severe vertigo, nausea, vomiting, anxiety, and pain. Viral etiology is most common, and recent history of an upper respiratory infection is common. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLabyrinthitis

Professional guidelines

PubMed

Vertigo and dizziness in childhood - update on diagnosis and treatment.
Jahn K, Langhagen T, Schroeder AS, Heinen F
Neuropediatrics 2011 Aug;42(4):129-34. Epub 2011 Jul 15 doi: 10.1055/s-0031-1283158. PMID: 21766267
Treatment of vertigo.
Swartz R, Longwell P
Am Fam Physician 2005 Mar 15;71(6):1115-22. PMID: 15791890
CT diagnosis and differential diagnosis of otodystrophic lesions of the temporal bone.
d'Archambeau O, Parizel PM, Koekelkoren E, Van de Heyning P, De Schepper AM
Eur J Radiol 1990 Jul-Aug;11(1):22-30. doi: 10.1016/0720-048x(90)90098-v. PMID: 2397727

Recent clinical studies

Etiology

Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Spontaneous Labyrinthine Hemorrhage: A Case Series.
Vivas EX, Panella NJ, Baugnon KL
Otolaryngol Head Neck Surg 2018 Nov;159(5):908-913. Epub 2018 Jul 3 doi: 10.1177/0194599818785900. PMID: 29966483
Contemporary surgical issues in paediatric cochlear implantation.
Wasson JD, Briggs RJ
Int J Audiol 2016;55 Suppl 2:S77-87. Epub 2016 Jun 7 doi: 10.1080/14992027.2016.1184765. PMID: 27266370
Otitis media in developing countries.
Berman S
Pediatrics 1995 Jul;96(1 Pt 1):126-31. PMID: 7596700
Human cytomegalovirus labyrinthitis.
Strauss M
Am J Otolaryngol 1990 Sep-Oct;11(5):292-8. doi: 10.1016/0196-0709(90)90057-3. PMID: 2176062

Diagnosis

Pediatric tinnitus: The role of neuroimaging.
Salman R, Chong I, Amans M, Hui F, Desai N, Huisman TAGM, Tran B
J Neuroimaging 2022 May;32(3):400-411. Epub 2022 Mar 20 doi: 10.1111/jon.12986. PMID: 35307901
Dizziness demystified.
Welgampola MS, Young AS, Pogson JM, Bradshaw AP, Halmagyi GM
Pract Neurol 2019 Dec;19(6):492-501. Epub 2019 Jul 20 doi: 10.1136/practneurol-2019-002199. PMID: 31326945
Dizziness.
Whitman GT
Am J Med 2018 Dec;131(12):1431-1437. Epub 2018 Jun 1 doi: 10.1016/j.amjmed.2018.05.014. PMID: 29859806
An approach to vertigo in general practice.
Dommaraju S, Perera E
Aust Fam Physician 2016 Apr;45(4):190-4. PMID: 27052132
Dizziness: a diagnostic approach.
Post RE, Dickerson LM
Am Fam Physician 2010 Aug 15;82(4):361-8, 369. PMID: 20704166

Therapy

Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Plinia cauliflora (Mart.) Kausel: A comprehensive ethnopharmacological review of a genuinely Brazilian species.
Gasparotto Junior A, de Souza P, Lívero FADR
J Ethnopharmacol 2019 Dec 5;245:112169. Epub 2019 Aug 16 doi: 10.1016/j.jep.2019.112169. PMID: 31425732
Contemporary surgical issues in paediatric cochlear implantation.
Wasson JD, Briggs RJ
Int J Audiol 2016;55 Suppl 2:S77-87. Epub 2016 Jun 7 doi: 10.1080/14992027.2016.1184765. PMID: 27266370
Nitrogen and oxygen molecules in meningitis-associated labyrinthitis and hearing impairment.
Klein M, Koedel U, Kastenbauer S, Pfister HW
Infection 2008 Feb;36(1):2-14. Epub 2007 Dec 14 doi: 10.1007/s15010-007-7153-1. PMID: 18084715
Antibiotic prophylaxis in clean and clean-contaminated ear surgery.
Verschuur HP, de Wever WW, van Benthem PP
Cochrane Database Syst Rev 2004;2004(3):CD003996. doi: 10.1002/14651858.CD003996.pub2. PMID: 15266512Free PMC Article

Prognosis

Non-Syndromic Sensorineural Hearing Loss in Children.
Robson CD, Lewis M, D'Arco F
Neuroimaging Clin N Am 2023 Nov;33(4):531-542. Epub 2023 Jul 11 doi: 10.1016/j.nic.2023.05.005. PMID: 37741656
Advanced imaging of head and neck infections.
Baba A, Kurokawa R, Kurokawa M, Reifeiss S, Policeni BA, Ota Y, Srinivasan A
J Neuroimaging 2023 Jul-Aug;33(4):477-492. Epub 2023 Mar 15 doi: 10.1111/jon.13099. PMID: 36922159
Acute mastoiditis in children.
Cassano P, Ciprandi G, Passali D
Acta Biomed 2020 Feb 17;91(1-S):54-59. doi: 10.23750/abm.v91i1-S.9259. PMID: 32073562Free PMC Article
Spontaneous Labyrinthine Hemorrhage: A Case Series.
Vivas EX, Panella NJ, Baugnon KL
Otolaryngol Head Neck Surg 2018 Nov;159(5):908-913. Epub 2018 Jul 3 doi: 10.1177/0194599818785900. PMID: 29966483
Positional dizziness.
Fife TD
Continuum (Minneap Minn) 2012 Oct;18(5 Neuro-otology):1060-85. doi: 10.1212/01.CON.0000418376.80099.24. PMID: 23042060

Clinical prediction guides

Long-Term Outcome of Cochlear Implantation in Post-meningitic Deafnes.
Altuntaş OM, Özkan B, Bajin D, Sennaroğlu G, Sennaroğlu L
J Int Adv Otol 2021 Nov;17(6):500-507. doi: 10.5152/iao.2021.21105. PMID: 35177386Free PMC Article
Complications of herpes zoster in children.
Kanamori K, Shoji K, Kinoshita N, Ishiguro A, Miyairi I
Pediatr Int 2019 Dec;61(12):1216-1220. Epub 2019 Dec 9 doi: 10.1111/ped.14025. PMID: 31628883
Spontaneous Labyrinthine Hemorrhage: A Case Series.
Vivas EX, Panella NJ, Baugnon KL
Otolaryngol Head Neck Surg 2018 Nov;159(5):908-913. Epub 2018 Jul 3 doi: 10.1177/0194599818785900. PMID: 29966483
Human cytomegalovirus labyrinthitis.
Strauss M
Am J Otolaryngol 1990 Sep-Oct;11(5):292-8. doi: 10.1016/0196-0709(90)90057-3. PMID: 2176062
Congenital cytomegalovirus and hearing loss: clinical and experimental observations.
Davis GL
Laryngoscope 1979 Oct;89(10 Pt 1):1681-8. doi: 10.1002/lary.5540891017. PMID: 228136

Recent systematic reviews

Plectranthus Species with Anti-Inflammatory and Analgesic Potential: A Systematic Review on Ethnobotanical and Pharmacological Findings.
Barbosa MO, Wilairatana P, Leite GML, Delmondes GA, Silva LYSD, Júnior SCA, Dantas LBR, Bezerra DS, Beltrão ICSL, Dias DQ, Ribeiro-Filho J, Felipe CFB, Coutinho HDM, Menezes IRA, Kerntopf Mendonça MR
Molecules 2023 Jul 26;28(15) doi: 10.3390/molecules28155653. PMID: 37570622Free PMC Article
Aetiology of Ludwig van Beethoven's hearing impairment: hypotheses over the past 100 years - A systematic review.
Thomas JP, Dazert S, Prescher A, Voelter C
Eur Arch Otorhinolaryngol 2021 Aug;278(8):2703-2712. Epub 2020 Nov 23 doi: 10.1007/s00405-020-06467-w. PMID: 33230590Free PMC Article
The prognostic value and pathophysiologic significance of three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging in idiopathic sudden sensorineural hearing loss: A systematic review and meta-analysis.
Lammers MJW, Young E, Fenton D, Lea J, Westerberg BD
Clin Otolaryngol 2019 Nov;44(6):1017-1025. Epub 2019 Oct 2 doi: 10.1111/coa.13432. PMID: 31532907
Cochlear implantation versus auditory brainstem implantation in bilateral total deafness after head trauma: personal experience and review of the literature.
Medina M, Di Lella F, Di Trapani G, Prasad SC, Bacciu A, Aristegui M, Russo A, Sanna M
Otol Neurotol 2014 Feb;35(2):260-70. doi: 10.1097/MAO.0000000000000235. PMID: 24448286
Antibiotic prophylaxis in clean and clean-contaminated ear surgery.
Verschuur HP, de Wever WW, van Benthem PP
Cochrane Database Syst Rev 2004;2004(3):CD003996. doi: 10.1002/14651858.CD003996.pub2. PMID: 15266512Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...