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Endolymphatic hydrops

MedGen UID:
60183
•Concept ID:
C0206586
•
Disease or Syndrome
Synonyms: Endolymphatic Hydrops; Hydrops, Endolymphatic
SNOMED CT: Endolymphatic hydrops (9794007); Cochlear hydrops (70831000119103); Labyrinthine hydrops (27621000119100)
 
Monarch Initiative: MONDO:0006744

Definition

An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndolymphatic hydrops

Professional guidelines

PubMed

Meniere disease subtyping: the direction of diagnosis and treatment in the future.
Zhang S, Guo Z, Tian E, Liu D, Wang J, Kong W
Expert Rev Neurother 2022 Feb;22(2):115-127. Epub 2022 Feb 22 doi: 10.1080/14737175.2022.2030221. PMID: 35057670
Clinical Practice Guideline: Ménière's Disease.
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(2_suppl):S1-S55. doi: 10.1177/0194599820909438. PMID: 32267799
Treatment of dizziness: an interdisciplinary update.
Spiegel R, Rust H, Baumann T, Friedrich H, Sutter R, Göldlin M, Rosin C, Müri R, Mantokoudis G, Bingisser R, Strupp M, Kalla R
Swiss Med Wkly 2017;147:w14566. Epub 2017 Dec 27 doi: 10.4414/smw.2017.14566. PMID: 29282702

Recent clinical studies

Etiology

Endolymphatic hydrops mimicking obstructive Eustachian tube dysfunction: preliminary experience and literature review.
Bächinger D, Eckhard AH, Röösli C, Veraguth D, Huber A, Dalbert A
Eur Arch Otorhinolaryngol 2021 Feb;278(2):561-565. Epub 2020 Jun 24 doi: 10.1007/s00405-020-06139-9. PMID: 32583181
Endolymphatic hydrops and ionic transporters: genetic and biohumoral aspects.
Teggi R, Carpini SD, Zagato L
J Neurol 2019 Sep;266(Suppl 1):47-51. Epub 2019 Jun 5 doi: 10.1007/s00415-019-09399-6. PMID: 31165925
The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière's disease on MRI.
Bernaerts A, Vanspauwen R, Blaivie C, van Dinther J, Zarowski A, Wuyts FL, Vanden Bossche S, Offeciers E, Casselman JW, De Foer B
Neuroradiology 2019 Apr;61(4):421-429. Epub 2019 Feb 5 doi: 10.1007/s00234-019-02155-7. PMID: 30719545Free PMC Article
Endolymphatic hydrops perspectives 2012.
Pierce NE, Antonelli PJ
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):416-9. doi: 10.1097/MOO.0b013e328357a6c8. PMID: 22902416
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826

Diagnosis

Vestibular migraine or Meniere's disease: a diagnostic dilemma.
Chen JY, Guo ZQ, Wang J, Liu D, Tian E, Guo JQ, Kong WJ, Zhang SL
J Neurol 2023 Apr;270(4):1955-1968. Epub 2022 Dec 23 doi: 10.1007/s00415-022-11532-x. PMID: 36562849Free PMC Article
The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière's disease on MRI.
Bernaerts A, Vanspauwen R, Blaivie C, van Dinther J, Zarowski A, Wuyts FL, Vanden Bossche S, Offeciers E, Casselman JW, De Foer B
Neuroradiology 2019 Apr;61(4):421-429. Epub 2019 Feb 5 doi: 10.1007/s00234-019-02155-7. PMID: 30719545Free PMC Article
Secondary Endolymphatic Hydrops.
Ferster APO, Cureoglu S, Keskin N, Paparella MM, Isildak H
Otol Neurotol 2017 Jun;38(5):774-779. doi: 10.1097/MAO.0000000000001377. PMID: 28306649Free PMC Article
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
What is Menière's disease? A contemporary re-evaluation of endolymphatic hydrops.
Gürkov R, Pyykö I, Zou J, Kentala E
J Neurol 2016 Apr;263 Suppl 1:S71-81. Epub 2016 Apr 15 doi: 10.1007/s00415-015-7930-1. PMID: 27083887Free PMC Article

Therapy

Clinical Practice Guideline: Ménière's Disease.
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(2_suppl):S1-S55. doi: 10.1177/0194599820909438. PMID: 32267799
Meniere's disease.
Nakashima T, Pyykkö I, Arroll MA, Casselbrant ML, Foster CA, Manzoor NF, Megerian CA, Naganawa S, Young YH
Nat Rev Dis Primers 2016 May 12;2:16028. doi: 10.1038/nrdp.2016.28. PMID: 27170253
Endolymphatic hydrops: pathophysiology and experimental models.
Salt AN, Plontke SK
Otolaryngol Clin North Am 2010 Oct;43(5):971-83. doi: 10.1016/j.otc.2010.05.007. PMID: 20713237Free PMC Article
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826
Ménière's disease.
Minor LB, Schessel DA, Carey JP
Curr Opin Neurol 2004 Feb;17(1):9-16. doi: 10.1097/00019052-200402000-00004. PMID: 15090872

Prognosis

Meniere disease subtyping: the direction of diagnosis and treatment in the future.
Zhang S, Guo Z, Tian E, Liu D, Wang J, Kong W
Expert Rev Neurother 2022 Feb;22(2):115-127. Epub 2022 Feb 22 doi: 10.1080/14737175.2022.2030221. PMID: 35057670
Imaging of the temporal bone.
Touska P, Connor SEJ
Clin Radiol 2020 Sep;75(9):658-674. Epub 2020 Jul 18 doi: 10.1016/j.crad.2020.06.013. PMID: 32690241
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
Endolymphatic hydrops perspectives 2012.
Pierce NE, Antonelli PJ
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):416-9. doi: 10.1097/MOO.0b013e328357a6c8. PMID: 22902416
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826

Clinical prediction guides

Pathogenesis and Etiology of Ménière Disease: A Scoping Review of a Century of Evidence.
Rizk HG, Mehta NK, Qureshi U, Yuen E, Zhang K, Nkrumah Y, Lambert PR, Liu YF, McRackan TR, Nguyen SA, Meyer TA
JAMA Otolaryngol Head Neck Surg 2022 Apr 1;148(4):360-368. doi: 10.1001/jamaoto.2021.4282. PMID: 35142800
Meniere disease subtyping: the direction of diagnosis and treatment in the future.
Zhang S, Guo Z, Tian E, Liu D, Wang J, Kong W
Expert Rev Neurother 2022 Feb;22(2):115-127. Epub 2022 Feb 22 doi: 10.1080/14737175.2022.2030221. PMID: 35057670
Quantification of endolymphatic hydrops and its correlation with Meniere's disease clinical features.
Sun Q, Jiang G, Xiong G, Sun W, Wen W, Wei F
Clin Otolaryngol 2021 Nov;46(6):1354-1361. Epub 2021 Aug 20 doi: 10.1111/coa.13847. PMID: 34390176
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826

Recent systematic reviews

Temporal changes in endolymphatic hydrops on MRI with or without intervention: A systematic review.
Mavrommatis MA, Kaul VF, Chow K, Fan CJ, Bellaire CP, Cosetti MK, Wanna GB, Perez E
Am J Otolaryngol 2023 Mar-Apr;44(2):103764. Epub 2022 Dec 28 doi: 10.1016/j.amjoto.2022.103764. PMID: 36587603
Systematic review of magnetic resonance imaging for diagnosis of Meniere disease.
Lopez-Escamez JA, Attyé A
J Vestib Res 2019;29(2-3):121-129. doi: 10.3233/VES-180646. PMID: 31356219
A systematic review and meta-analysis of extratympanic electrocochleography in Ménière's disease diagnosis.
Ayub A, Qi L, Nunez DA
Int J Audiol 2019 Sep;58(9):533-540. Epub 2019 May 8 doi: 10.1080/14992027.2019.1606947. PMID: 31066337
Diagnostic Value of Vestibular Evoked Myogenic Potentials in Endolymphatic Hydrops: A Meta-Analysis.
Zhang S, Leng Y, Liu B, Shi H, Lu M, Kong W
Sci Rep 2015 Oct 12;5:14951. doi: 10.1038/srep14951. PMID: 26455332Free PMC Article
Electrocochleography for Ménière's disease: is it reliable?
Lamounier P, Gobbo DA, Souza TS, Oliveira CA, Bahmad F Jr
Braz J Otorhinolaryngol 2014 Nov-Dec;80(6):527-32. Epub 2014 Aug 27 doi: 10.1016/j.bjorl.2014.08.010. PMID: 25443316Free PMC Article

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