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Acneiform eruption

MedGen UID:
61219
•Concept ID:
C0175167
•
Finding
Synonyms: Acneiform Eruption; Acneiform Eruptions; Eruption, Acneiform; Eruptions, Acneiform
SNOMED CT: Acneiform eruption (402644006); Acneform eruptions (402644006)

Definition

Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcneiform eruption

Professional guidelines

PubMed

Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study.
Avallone G, Mastorino L, Tavoletti G, Macagno N, Barei F, Schena D, Rossi M, Magnaterra E, Antonelli F, Babino G, Viola R, Gargiulo L, Conforti C, Rapparini L, Errichetti E, Patruno C, Ruggiero P, Roccuzzo G, Maronese CA, Girolomoni G, Gola M, Chiricozzi A, Balato A, Ambrogio F, Narcisi A, Zalaudek I, Gurioli C, Napolitano M, Marzano AV, Foti C, Costanzo A, Piraccini BM, Ferrucci SM, Ortoncelli M, Quaglino P, Ribero S
J Am Acad Dermatol 2024 May;90(5):1031-1034. Epub 2024 Jan 9 doi: 10.1016/j.jaad.2024.01.004. PMID: 38199282
Clinical characteristics and treatment outcomes of Pityrosporum folliculitis in immunocompetent patients.
Green M, Feschuk AM, Kashetsky N, Maibach HI
Arch Dermatol Res 2023 Aug;315(6):1497-1509. Epub 2022 Dec 14 doi: 10.1007/s00403-022-02506-0. PMID: 36517586Free PMC Article
Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492

Recent clinical studies

Etiology

Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study.
Avallone G, Mastorino L, Tavoletti G, Macagno N, Barei F, Schena D, Rossi M, Magnaterra E, Antonelli F, Babino G, Viola R, Gargiulo L, Conforti C, Rapparini L, Errichetti E, Patruno C, Ruggiero P, Roccuzzo G, Maronese CA, Girolomoni G, Gola M, Chiricozzi A, Balato A, Ambrogio F, Narcisi A, Zalaudek I, Gurioli C, Napolitano M, Marzano AV, Foti C, Costanzo A, Piraccini BM, Ferrucci SM, Ortoncelli M, Quaglino P, Ribero S
J Am Acad Dermatol 2024 May;90(5):1031-1034. Epub 2024 Jan 9 doi: 10.1016/j.jaad.2024.01.004. PMID: 38199282
Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: A multi-institutional cohort study.
Zhang S, Tang K, Wan G, Nguyen N, Lu C, Ugwu-Dike P, Raval N, Seo J, Alexander NA, Jairath R, Phillipps J, Leung BW, Roster K, Chen W, Zubiri L, Boland G, Chen ST, Tsao H, Demehri S, LeBoeuf NR, Reynolds KL, Yu KH, Gusev A, Kwatra SG, Semenov YR
J Am Acad Dermatol 2023 May;88(5):1024-1032. Epub 2023 Feb 2 doi: 10.1016/j.jaad.2022.12.048. PMID: 36736626Free PMC Article
Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature.
Veraldi S, Benardon S, Diani M, Barbareschi M
J Cosmet Dermatol 2018 Feb;17(1):112-115. Epub 2017 Jun 8 doi: 10.1111/jocd.12360. PMID: 28594082
The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies.
Segaert S, Tabernero J, Chosidow O, Dirschka T, Elsner J, Mancini L, Maughan T, Morere JF, Santoro A, Sobrero A, Van Cutsem E, Layton A
J Dtsch Dermatol Ges 2005 Aug;3(8):599-606. doi: 10.1111/j.1610-0387.2005.05058.x. PMID: 16033478
Behçet's disease.
Sanchez-Negron FA
Dermatol Online J 2004 Nov 30;10(3):14. PMID: 15748584

Diagnosis

Acneiform eruption secondary to radiotherapy.
Liu W, Liu JW, Ma DL
Indian J Dermatol Venereol Leprol 2021 [SEASON];87(4):587-588. doi: 10.4103/ijdvl.IJDVL_421_19. PMID: 31929232
Acneiform follicular mucinosis: an indolent follicular mucinosis variant unrelated to mycosis fungoides?
Geller S, Pulitzer M, Myskowski PL
Clin Exp Dermatol 2018 Dec;43(8):921-924. Epub 2018 May 30 doi: 10.1111/ced.13671. PMID: 29851124Free PMC Article
Drug-induced acneiform eruption.
Du-Thanh A, Kluger N, Bensalleh H, Guillot B
Am J Clin Dermatol 2011 Aug 1;12(4):233-45. doi: 10.2165/11588900-000000000-00000. PMID: 21668032
Aripiprazole-induced acneiform eruption.
Mishra B, Praharaj SK, Prakash R, Sinha VK
Gen Hosp Psychiatry 2008 Sep-Oct;30(5):479-81. Epub 2008 Jul 23 doi: 10.1016/j.genhosppsych.2008.02.004. PMID: 18774434
Perioral dermatitis: an acneiform eruption.
Kuflik JH, Janniger CK, Piela Z
Cutis 2001 Jan;67(1):21-2. PMID: 11204598

Therapy

Trichomegaly Due to Panitumumab.
Taboada Paz L, Vicente Basanta E, Monteagudo Sánchez B
JAMA Dermatol 2024 Jun 1;160(6):667. doi: 10.1001/jamadermatol.2024.0642. PMID: 38656343
Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study.
Avallone G, Mastorino L, Tavoletti G, Macagno N, Barei F, Schena D, Rossi M, Magnaterra E, Antonelli F, Babino G, Viola R, Gargiulo L, Conforti C, Rapparini L, Errichetti E, Patruno C, Ruggiero P, Roccuzzo G, Maronese CA, Girolomoni G, Gola M, Chiricozzi A, Balato A, Ambrogio F, Narcisi A, Zalaudek I, Gurioli C, Napolitano M, Marzano AV, Foti C, Costanzo A, Piraccini BM, Ferrucci SM, Ortoncelli M, Quaglino P, Ribero S
J Am Acad Dermatol 2024 May;90(5):1031-1034. Epub 2024 Jan 9 doi: 10.1016/j.jaad.2024.01.004. PMID: 38199282
Bromide-Induced Acneiform Eruption.
Endo R, Tanaka R, Nomura T
Dermatitis 2023 Jul-Aug;34(4):276-277. Epub 2023 Jan 19 doi: 10.1089/derm.2022.0047. PMID: 36917540
Erlotinib-induced pustular eruption.
Cusano F, Ferrara G, Barletta E, Ingordo V
G Ital Dermatol Venereol 2009 Feb;144(1):93-6. PMID: 19218915
Aripiprazole-induced acneiform eruption.
Mishra B, Praharaj SK, Prakash R, Sinha VK
Gen Hosp Psychiatry 2008 Sep-Oct;30(5):479-81. Epub 2008 Jul 23 doi: 10.1016/j.genhosppsych.2008.02.004. PMID: 18774434

Prognosis

Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature.
Veraldi S, Benardon S, Diani M, Barbareschi M
J Cosmet Dermatol 2018 Feb;17(1):112-115. Epub 2017 Jun 8 doi: 10.1111/jocd.12360. PMID: 28594082
Drug-induced acneiform eruption.
Du-Thanh A, Kluger N, Bensalleh H, Guillot B
Am J Clin Dermatol 2011 Aug 1;12(4):233-45. doi: 10.2165/11588900-000000000-00000. PMID: 21668032
Erlotinib-induced pustular eruption.
Cusano F, Ferrara G, Barletta E, Ingordo V
G Ital Dermatol Venereol 2009 Feb;144(1):93-6. PMID: 19218915
Estrogen dermatitis: a dendritic-cell-mediated allergic condition.
Yotsumoto S, Shimomai K, Hashiguchi T, Uchimiya H, Usuki K, Nishi M, Kanekura T, Kanzaki T
Dermatology 2003;207(3):265-8. doi: 10.1159/000073088. PMID: 14571068
Steroid acne after orthognathic surgery.
Precious DS, Hoffman CD, Miller R
Oral Surg Oral Med Oral Pathol 1992 Sep;74(3):279-81. doi: 10.1016/0030-4220(92)90058-x. PMID: 1407985

Clinical prediction guides

Acneiform eruption induced by molecularly targeted agents in antineoplastic therapy: A review.
Yuan C, Wang B
J Cosmet Dermatol 2023 Aug;22(8):2150-2157. Epub 2023 Mar 16 doi: 10.1111/jocd.15704. PMID: 36924348
Nevoid melanoma and eruptive nevi from erlotinib.
Seidman JS, Eichenfield DZ, Orme CM
Dermatol Online J 2020 Jun 15;26(6) PMID: 32815691
Hypofractionated radiotherapy combined with cetuximab in vulnerable elderly patients with locally advanced head and neck squamous cell carcinoma.
De Felice F, Vetrone L, Bulzonetti N, Caiazzo R, Marampon F, Musio D, Tombolini V
Med Oncol 2019 Jun 12;36(8):68. doi: 10.1007/s12032-019-1292-y. PMID: 31190132
A first case report of diffuse acneiform eruption caused by capecitabine in a patient with small-cell neuroendocrine lung carcinoma.
Kara A, Alatas E, Dogan G, Celik SY, Tanriverdi O
J Oncol Pharm Pract 2016 Oct;22(5):717-9. Epub 2015 May 20 doi: 10.1177/1078155215587542. PMID: 25994157
Erlotinib-induced pustular eruption.
Cusano F, Ferrara G, Barletta E, Ingordo V
G Ital Dermatol Venereol 2009 Feb;144(1):93-6. PMID: 19218915

Recent systematic reviews

Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492
A systematic review of oral retinoids for treatment of acneiform eruptions induced by epidermal growth factor receptor inhibitors.
Bierbrier R, Lam M, Pehr K
Dermatol Ther 2022 May;35(5):e15412. Epub 2022 Mar 3 doi: 10.1111/dth.15412. PMID: 35220635
Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review.
Yu J, Chen JK, Mowad CM, Reeder M, Hylwa S, Chisolm S, Dunnick CA, Goldminz AM, Jacob SE, Wu PA, Zippin J, Atwater AR
J Am Acad Dermatol 2021 Feb;84(2):486-494. Epub 2020 Oct 1 doi: 10.1016/j.jaad.2020.09.074. PMID: 33011325Free PMC Article

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