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Acneiform eruption

MedGen UID:
61219
•Concept ID:
C0175167
•
Finding
Synonyms: Acneiform Eruption; Acneiform Eruptions; Eruption, Acneiform; Eruptions, Acneiform
SNOMED CT: Acneiform eruption (402644006); Acneform eruptions (402644006)

Definition

Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcneiform eruption

Professional guidelines

PubMed

Clinical characteristics and treatment outcomes of Pityrosporum folliculitis in immunocompetent patients.
Green M, Feschuk AM, Kashetsky N, Maibach HI
Arch Dermatol Res 2023 Aug;315(6):1497-1509. Epub 2022 Dec 14 doi: 10.1007/s00403-022-02506-0. PMID: 36517586Free PMC Article
Acneiform Eruption Following Elexacaftor-Tezacaftor-Ivacaftor Treatment in Patients With Cystic Fibrosis.
Okroglic L, Sohier P, Martin C, Lheure C, Franck N, Honoré I, Kanaan R, Burgel PR, Carlotti A, Dupin N, Oulès B
JAMA Dermatol 2023 Jan 1;159(1):68-72. doi: 10.1001/jamadermatol.2022.5208. PMID: 36449298Free PMC Article
Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492

Recent clinical studies

Etiology

Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: A multi-institutional cohort study.
Zhang S, Tang K, Wan G, Nguyen N, Lu C, Ugwu-Dike P, Raval N, Seo J, Alexander NA, Jairath R, Phillipps J, Leung BW, Roster K, Chen W, Zubiri L, Boland G, Chen ST, Tsao H, Demehri S, LeBoeuf NR, Reynolds KL, Yu KH, Gusev A, Kwatra SG, Semenov YR
J Am Acad Dermatol 2023 May;88(5):1024-1032. Epub 2023 Feb 2 doi: 10.1016/j.jaad.2022.12.048. PMID: 36736626Free PMC Article
Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492
A systematic review of oral retinoids for treatment of acneiform eruptions induced by epidermal growth factor receptor inhibitors.
Bierbrier R, Lam M, Pehr K
Dermatol Ther 2022 May;35(5):e15412. Epub 2022 Mar 3 doi: 10.1111/dth.15412. PMID: 35220635
Duration of Oral Antibiotics Administration for Cetuximab-Induced Acneiform Eruption.
Park JH, Choi Y, Kim HJ, Oh SJ, Lee DY, Lee JH, Lee JH
Dermatology 2021;237(3):457-463. Epub 2020 Dec 10 doi: 10.1159/000511623. PMID: 33302268
Cetuximab-induced cutaneous toxicity.
Tomková H, Kohoutek M, Zábojníková M, Pospísková M, Ostrízková L, Gharibyar M
J Eur Acad Dermatol Venereol 2010 Jun;24(6):692-6. Epub 2009 Nov 18 doi: 10.1111/j.1468-3083.2009.03490.x. PMID: 19925598

Diagnosis

Clinical characteristics and treatment outcomes of Pityrosporum folliculitis in immunocompetent patients.
Green M, Feschuk AM, Kashetsky N, Maibach HI
Arch Dermatol Res 2023 Aug;315(6):1497-1509. Epub 2022 Dec 14 doi: 10.1007/s00403-022-02506-0. PMID: 36517586Free PMC Article
Clinicopathological differentiation between Pityrosporum folliculitis and acneiform eruption.
An MK, Hong EH, Cho EB, Park EJ, Kim KH, Kim KJ
J Dermatol 2019 Nov;46(11):978-984. Epub 2019 Sep 5 doi: 10.1111/1346-8138.15070. PMID: 31489692
Management of Dermatologic Complications of Lung Cancer Therapies.
Pugliese SB, Neal JW, Kwong BY
Curr Treat Options Oncol 2015 Oct;16(10):50. doi: 10.1007/s11864-015-0368-y. PMID: 26338208
Acneiform eruptions.
Dessinioti C, Antoniou C, Katsambas A
Clin Dermatol 2014 Jan-Feb;32(1):24-34. doi: 10.1016/j.clindermatol.2013.05.023. PMID: 24314375
Drug-induced acneiform eruption.
Du-Thanh A, Kluger N, Bensalleh H, Guillot B
Am J Clin Dermatol 2011 Aug 1;12(4):233-45. doi: 10.2165/11588900-000000000-00000. PMID: 21668032

Therapy

Acneiform eruption induced by molecularly targeted agents in antineoplastic therapy: A review.
Yuan C, Wang B
J Cosmet Dermatol 2023 Aug;22(8):2150-2157. Epub 2023 Mar 16 doi: 10.1111/jocd.15704. PMID: 36924348
Bromide-Induced Acneiform Eruption.
Endo R, Tanaka R, Nomura T
Dermatitis 2023 Jul-Aug;34(4):276-277. Epub 2023 Jan 19 doi: 10.1089/derm.2022.0047. PMID: 36917540
Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492
Cetuximab-induced cutaneous toxicity.
Tomková H, Kohoutek M, Zábojníková M, Pospísková M, Ostrízková L, Gharibyar M
J Eur Acad Dermatol Venereol 2010 Jun;24(6):692-6. Epub 2009 Nov 18 doi: 10.1111/j.1468-3083.2009.03490.x. PMID: 19925598
Acne and systemic disease.
Lolis MS, Bowe WP, Shalita AR
Med Clin North Am 2009 Nov;93(6):1161-81. doi: 10.1016/j.mcna.2009.08.008. PMID: 19932324

Prognosis

Acneiform eruptions with combination targeted cancer therapy in colorectal cancer patients.
Ibraheim MK, Lo J, Gupta R, Parseghian C, Patel AB
Support Care Cancer 2022 Oct;30(10):8051-8058. Epub 2022 Jun 30 doi: 10.1007/s00520-022-07257-2. PMID: 35771289
Instrumental evaluation sensitively detects subclinical skin changes by the epidermal growth factor receptor inhibitors and risk factors for severe acneiform eruption.
Kikuchi K, Nozawa K, Yamazaki N, Nakai Y, Higashiyama A, Asano M, Fujiwara Y, Kanda S, Ohe Y, Takashima A, Boku N, Inoue A, Takahashi M, Mori T, Taguchi O, Inoue Y, Mizutani H
J Dermatol 2019 Jan;46(1):18-25. Epub 2018 Nov 7 doi: 10.1111/1346-8138.14691. PMID: 30402978
Drug-induced acneiform eruption.
Du-Thanh A, Kluger N, Bensalleh H, Guillot B
Am J Clin Dermatol 2011 Aug 1;12(4):233-45. doi: 10.2165/11588900-000000000-00000. PMID: 21668032
Cetuximab-induced cutaneous toxicity.
Tomková H, Kohoutek M, Zábojníková M, Pospísková M, Ostrízková L, Gharibyar M
J Eur Acad Dermatol Venereol 2010 Jun;24(6):692-6. Epub 2009 Nov 18 doi: 10.1111/j.1468-3083.2009.03490.x. PMID: 19925598
Erlotinib-induced pustular eruption.
Cusano F, Ferrara G, Barletta E, Ingordo V
G Ital Dermatol Venereol 2009 Feb;144(1):93-6. PMID: 19218915

Clinical prediction guides

Acneiform eruption induced by molecularly targeted agents in antineoplastic therapy: A review.
Yuan C, Wang B
J Cosmet Dermatol 2023 Aug;22(8):2150-2157. Epub 2023 Mar 16 doi: 10.1111/jocd.15704. PMID: 36924348
Acneiform Eruption Following Elexacaftor-Tezacaftor-Ivacaftor Treatment in Patients With Cystic Fibrosis.
Okroglic L, Sohier P, Martin C, Lheure C, Franck N, Honoré I, Kanaan R, Burgel PR, Carlotti A, Dupin N, Oulès B
JAMA Dermatol 2023 Jan 1;159(1):68-72. doi: 10.1001/jamadermatol.2022.5208. PMID: 36449298Free PMC Article
Tumorous formation of the forehead.
Temelkova I, Tchernev G
Wien Med Wochenschr 2020 May;170(7-8):196-198. Epub 2020 Jan 28 doi: 10.1007/s10354-019-00730-4. PMID: 31993874
Clinicopathological differentiation between Pityrosporum folliculitis and acneiform eruption.
An MK, Hong EH, Cho EB, Park EJ, Kim KH, Kim KJ
J Dermatol 2019 Nov;46(11):978-984. Epub 2019 Sep 5 doi: 10.1111/1346-8138.15070. PMID: 31489692
Cetuximab-induced cutaneous toxicity.
Tomková H, Kohoutek M, Zábojníková M, Pospísková M, Ostrízková L, Gharibyar M
J Eur Acad Dermatol Venereol 2010 Jun;24(6):692-6. Epub 2009 Nov 18 doi: 10.1111/j.1468-3083.2009.03490.x. PMID: 19925598

Recent systematic reviews

Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.
Gorji M, Joseph J, Pavlakis N, Smith SD
Asia Pac J Clin Oncol 2022 Dec;18(6):526-539. Epub 2022 Mar 29 doi: 10.1111/ajco.13740. PMID: 35352492
A systematic review of oral retinoids for treatment of acneiform eruptions induced by epidermal growth factor receptor inhibitors.
Bierbrier R, Lam M, Pehr K
Dermatol Ther 2022 May;35(5):e15412. Epub 2022 Mar 3 doi: 10.1111/dth.15412. PMID: 35220635
Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review.
Yu J, Chen JK, Mowad CM, Reeder M, Hylwa S, Chisolm S, Dunnick CA, Goldminz AM, Jacob SE, Wu PA, Zippin J, Atwater AR
J Am Acad Dermatol 2021 Feb;84(2):486-494. Epub 2020 Oct 1 doi: 10.1016/j.jaad.2020.09.074. PMID: 33011325Free PMC Article

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