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Acne vulgaris

MedGen UID:
95
Concept ID:
C0001144
Disease or Syndrome
Synonym: Acne Vulgaris
SNOMED CT: Acne vulgaris (88616000); Common acne (88616000)

Definition

An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcne vulgaris

Professional guidelines

PubMed

Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS
J Am Acad Dermatol 2024 May;90(5):1006.e1-1006.e30. Epub 2024 Jan 30 doi: 10.1016/j.jaad.2023.12.017. PMID: 38300170
Soliman YS, Horowitz R, Hashim PW, Nia JK, Farberg AS, Goldenberg G
Cutis 2018 Jul;102(1):21;25;47;48. PMID: 30138491
Rolfe HM
J Cosmet Dermatol 2014 Dec;13(4):324-8. doi: 10.1111/jocd.12119. PMID: 25399625

Recent clinical studies

Etiology

Kutlu Ö, Karadağ AS, Wollina U
An Bras Dermatol 2023 Jan-Feb;98(1):75-83. Epub 2022 Oct 14 doi: 10.1016/j.abd.2022.01.006. PMID: 36253244Free PMC Article
Oge' LK, Broussard A, Marshall MD
Am Fam Physician 2019 Oct 15;100(8):475-484. PMID: 31613567
Degitz K, Ochsendorf F
J Dtsch Dermatol Ges 2017 Jul;15(7):709-722. doi: 10.1111/ddg.30_13278. PMID: 28677193
Stein Gold LF
Semin Cutan Med Surg 2016 Jun;35(6 Suppl):S114-6. doi: 10.12788/j.sder.2016.036. PMID: 27538054
Robertson KM
Facial Plast Surg Clin North Am 2004 Aug;12(3):347-55, vi. doi: 10.1016/j.fsc.2004.03.002. PMID: 15261171

Diagnosis

Cho M, Woo YR, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2023 Dec 11;103:adv18392. doi: 10.2340/actadv.v103.18392. PMID: 38078688Free PMC Article
Heath CR, Usatine RP
Cutis 2021 Sep;108(3):167. doi: 10.12788/cutis.0339. PMID: 34826281
Heath CR, Usatine RP
J Fam Pract 2021 Sep;70(7):356. doi: 10.12788/jfp.0271. PMID: 34818170
Dursun R, Daye M, Durmaz K
Dermatol Ther 2019 Sep;32(5):e13020. Epub 2019 Jul 22 doi: 10.1111/dth.13020. PMID: 31294907
Zaenglein AL
N Engl J Med 2018 Oct 4;379(14):1343-1352. doi: 10.1056/NEJMcp1702493. PMID: 30281982

Therapy

Sitohang IBS, Sirait SAP, Suryanegara J
Int Wound J 2021 Oct;18(5):577-585. Epub 2021 Feb 3 doi: 10.1111/iwj.13559. PMID: 33538106Free PMC Article
Schoenberg E, O'Connor M, Wang JV, Yang S, Saedi N
J Cosmet Dermatol 2020 Jan;19(1):112-114. Epub 2019 May 9 doi: 10.1111/jocd.12988. PMID: 31070298
Hou A, Cohen B, Haimovic A, Elbuluk N
Dermatol Surg 2017 Mar;43(3):321-339. doi: 10.1097/DSS.0000000000000924. PMID: 27755171
Foster RH, Brogden RN, Benfield P
Drugs 1998 May;55(5):705-11; discussion 712. doi: 10.2165/00003495-199855050-00008. PMID: 9585866
Cotterill JA
Acta Derm Venereol Suppl (Stockh) 1980;Suppl 89:57-63. PMID: 6162349

Prognosis

Horwitz H, Andersen JT, Dalhoff KP
J Intern Med 2019 Mar;285(3):333-340. Epub 2018 Nov 20 doi: 10.1111/joim.12850. PMID: 30460728
Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS, Bowe WP, Graber EM, Harper JC, Kang S, Keri JE, Leyden JJ, Reynolds RV, Silverberg NB, Stein Gold LF, Tollefson MM, Weiss JS, Dolan NC, Sagan AA, Stern M, Boyer KM, Bhushan R
J Am Acad Dermatol 2016 May;74(5):945-73.e33. Epub 2016 Feb 17 doi: 10.1016/j.jaad.2015.12.037. PMID: 26897386
Pezza M, Carlomagno V, Casucci G
G Ital Dermatol Venereol 2015 Dec;150(6):649-53. Epub 2014 Jul 31 PMID: 25077885
Williams HC, Dellavalle RP, Garner S
Lancet 2012 Jan 28;379(9813):361-72. Epub 2011 Aug 29 doi: 10.1016/S0140-6736(11)60321-8. PMID: 21880356
Robertson KM
Facial Plast Surg Clin North Am 2004 Aug;12(3):347-55, vi. doi: 10.1016/j.fsc.2004.03.002. PMID: 15261171

Clinical prediction guides

Guertler A, Volsky A, Eijkenboom Q, Fiedler T, French LE, Reinholz M
Nutrients 2023 Oct 17;15(20) doi: 10.3390/nu15204405. PMID: 37892480Free PMC Article
Santer M, Lawrence M, Renz S, Eminton Z, Stuart B, Sach TH, Pyne S, Ridd MJ, Francis N, Soulsby I, Thomas K, Permyakova N, Little P, Muller I, Nuttall J, Griffiths G, Thomas KS, Layton AM; SAFA trial investigators
BMJ 2023 May 16;381:e074349. doi: 10.1136/bmj-2022-074349. PMID: 37192767Free PMC Article
Berry K, Lim J, Zaenglein AL
Pediatr Ann 2020 Mar 1;49(3):e109-e115. doi: 10.3928/19382359-20200211-01. PMID: 32155276
Huang YC, Cheng YC
J Am Acad Dermatol 2017 Jun;76(6):1068-1076.e9. Epub 2017 Mar 11 doi: 10.1016/j.jaad.2016.12.028. PMID: 28291553
Adityan B, Kumari R, Thappa DM
Indian J Dermatol Venereol Leprol 2009 May-Jun;75(3):323-6. doi: 10.4103/0378-6323.51258. PMID: 19439902

Recent systematic reviews

Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS
J Am Acad Dermatol 2024 May;90(5):1006.e1-1006.e30. Epub 2024 Jan 30 doi: 10.1016/j.jaad.2023.12.017. PMID: 38300170
Mavranezouli I, Daly CH, Welton NJ, Deshpande S, Berg L, Bromham N, Arnold S, Phillippo DM, Wilcock J, Xu J, Ravenscroft JC, Wood D, Rafiq M, Fou L, Dworzynski K, Healy E
Br J Dermatol 2022 Nov;187(5):639-649. Epub 2022 Aug 22 doi: 10.1111/bjd.21739. PMID: 35789996Free PMC Article
Yee BE, Richards P, Sui JY, Marsch AF
Dermatol Ther 2020 Nov;33(6):e14252. Epub 2020 Sep 15 doi: 10.1111/dth.14252. PMID: 32860489
Heng AHS, Chew FT
Sci Rep 2020 Apr 1;10(1):5754. doi: 10.1038/s41598-020-62715-3. PMID: 32238884Free PMC Article
Fiedler F, Stangl GI, Fiedler E, Taube KM
Acta Derm Venereol 2017 Jan 4;97(1):7-9. doi: 10.2340/00015555-2450. PMID: 27136757

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