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Specific language impairment

MedGen UID:
627772
•Concept ID:
C0454651
•
Disease or Syndrome
Synonyms: Disorder, Specific Language; Disorders, Specific Language; Impairment, Specific Language; Impairments, Specific Language; Language Disorder, Specific; Language Disorders, Specific; Language Impairment, Specific; Language Impairments, Specific; Specific Language Disorder; Specific Language Disorders; Specific Language Impairment; Specific Language Impairments
SNOMED CT: Specific language disorder (229746007); Specific language impairment (229746007)
 
Monarch Initiative: MONDO:0000724
OMIM® Phenotypic series: PS606711
Orphanet: ORPHA458713

Definition

A language disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpecific language impairment

Professional guidelines

PubMed

Five overarching factors central to grammatical learning and treatment in children with developmental language disorder.
Leonard LB, Kueser JB
Int J Lang Commun Disord 2019 May;54(3):347-361. Epub 2019 Feb 7 doi: 10.1111/1460-6984.12456. PMID: 30729604Free PMC Article
Working memory and specific language impairment: an update on the relation and perspectives on assessment and treatment.
Montgomery JW, Magimairaj BM, Finney MC
Am J Speech Lang Pathol 2010 Feb;19(1):78-94. Epub 2009 Nov 30 doi: 10.1044/1058-0360(2009/09-0028). PMID: 19948760
Heritability of specific language impairment depends on diagnostic criteria.
Bishop DV, Hayiou-Thomas ME
Genes Brain Behav 2008 Apr;7(3):365-72. Epub 2007 Oct 4 doi: 10.1111/j.1601-183X.2007.00360.x. PMID: 17919296Free PMC Article

Recent clinical studies

Etiology

Advances in Specific Language Impairment Research and Intervention: An Overview of Five Research Symposium Papers.
Rice ML
J Speech Lang Hear Res 2020 Oct 16;63(10):3219-3223. doi: 10.1044/2020_JSLHR-20-00504. PMID: 33064602Free PMC Article
Alliteration and rhyme skills in children with specific language impairment.
Pedott PR, Cáceres-Assenço AM, Befi-Lopes DM
Codas 2017 Mar 30;29(2):e20160017. doi: 10.1590/2317-1782/20172016017. PMID: 28380200
Metacognitive Strategies.
Schiff R, Nuri Ben-Shushan Y, Ben-Artzi E
J Learn Disabil 2017 Mar/Apr;50(2):143-157. Epub 2016 Aug 4 doi: 10.1177/0022219415589847. PMID: 26054726
Theory of mind and specific language impairment in school-age children.
Spanoudis G
J Commun Disord 2016 May-Jun;61:83-96. Epub 2016 Apr 11 doi: 10.1016/j.jcomdis.2016.04.003. PMID: 27089201
Genetics of speech and language disorders.
Kang C, Drayna D
Annu Rev Genomics Hum Genet 2011;12:145-64. doi: 10.1146/annurev-genom-090810-183119. PMID: 21663442

Diagnosis

Language disorders.
Paul R
Handb Clin Neurol 2020;174:21-35. doi: 10.1016/B978-0-444-64148-9.00002-8. PMID: 32977879
Specific language impairment: a convenient label for whom?
Reilly S, Tomblin B, Law J, McKean C, Mensah FK, Morgan A, Goldfeld S, Nicholson JM, Wake M
Int J Lang Commun Disord 2014 Jul-Aug;49(4):416-51. doi: 10.1111/1460-6984.12102. PMID: 25142091Free PMC Article
Diagnosing developmental coordination disorders.
Kirby A, Sugden D, Purcell C
Arch Dis Child 2014 Mar;99(3):292-6. Epub 2013 Nov 19 doi: 10.1136/archdischild-2012-303569. PMID: 24255567
Specific language impairment.
Kamhi AG, Clark MK
Handb Clin Neurol 2013;111:219-27. doi: 10.1016/B978-0-444-52891-9.00022-1. PMID: 23622167
Early language delay and specific language impairment.
Moyle J, Stokes SF, Klee T
Dev Disabil Res Rev 2011;17(2):160-9. doi: 10.1002/ddrr.1110. PMID: 23362035

Therapy

Meta-analysis reveals low language capacity in childhood is associated with mental health problems in adulthood.
Lim SWY, Lum JAG
Int J Lang Commun Disord 2024 Nov-Dec;59(6):2985-3003. Epub 2024 Oct 19 doi: 10.1111/1460-6984.13125. PMID: 39425956
Task-irrelevant auditory metre shapes visuomotor sequential learning.
MacIntyre AD, Lo HYJ, Cross I, Scott S
Psychol Res 2023 Apr;87(3):872-893. Epub 2022 Jun 12 doi: 10.1007/s00426-022-01690-y. PMID: 35690927Free PMC Article
The Relationship Between Language and Planning in Children With Language Impairment.
Larson C, Gangopadhyay I, Kaushanskaya M, Weismer SE
J Speech Lang Hear Res 2019 Aug 15;62(8):2772-2784. Epub 2019 Jul 24 doi: 10.1044/2019_JSLHR-L-18-0367. PMID: 31343936Free PMC Article
Population-based screening of children for specific speech and language impairment in Germany: a systematic review.
Kasper J, Kreis J, Scheibler F, Möller D, Skipka G, Lange S, von dem Knesebeck O
Folia Phoniatr Logop 2011;63(5):247-63. Epub 2011 Feb 8 doi: 10.1159/000321000. PMID: 21304231
Is specific language impairment a valid diagnostic category? Genetic and psycholinguistic evidence.
Bishop DV
Philos Trans R Soc Lond B Biol Sci 1994 Oct 29;346(1315):105-11. doi: 10.1098/rstb.1994.0134. PMID: 7886145

Prognosis

Statistical Learning and Language Impairments: Toward More Precise Theoretical Accounts.
Bogaerts L, Siegelman N, Frost R
Perspect Psychol Sci 2021 Mar;16(2):319-337. Epub 2020 Nov 2 doi: 10.1177/1745691620953082. PMID: 33136519Free PMC Article
Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology.
Bishop DVM, Snowling MJ, Thompson PA, Greenhalgh T; and the CATALISE-2 consortium
J Child Psychol Psychiatry 2017 Oct;58(10):1068-1080. Epub 2017 Mar 30 doi: 10.1111/jcpp.12721. PMID: 28369935Free PMC Article
Theory of mind and specific language impairment in school-age children.
Spanoudis G
J Commun Disord 2016 May-Jun;61:83-96. Epub 2016 Apr 11 doi: 10.1016/j.jcomdis.2016.04.003. PMID: 27089201
The Development of English as a Second Language With and Without Specific Language Impairment: Clinical Implications.
Paradis J
J Speech Lang Hear Res 2016 Feb;59(1):171-82. doi: 10.1044/2015_JSLHR-L-15-0008. PMID: 26501845
Early language delay and specific language impairment.
Moyle J, Stokes SF, Klee T
Dev Disabil Res Rev 2011;17(2):160-9. doi: 10.1002/ddrr.1110. PMID: 23362035

Clinical prediction guides

Teacher Educational Decision Making for Children With Specific Language Impairment.
Girolamo TM, Rice ML, Selin CM, Wang CJ
Am J Speech Lang Pathol 2022 May 10;31(3):1221-1243. Epub 2022 Mar 2 doi: 10.1044/2021_AJSLP-20-00366. PMID: 35235411Free PMC Article
Statistical Learning and Language Impairments: Toward More Precise Theoretical Accounts.
Bogaerts L, Siegelman N, Frost R
Perspect Psychol Sci 2021 Mar;16(2):319-337. Epub 2020 Nov 2 doi: 10.1177/1745691620953082. PMID: 33136519Free PMC Article
Intrafamilial phenotypic variability of Specific Language Impairment.
Bartha-Doering L, Regele S, Deuster D, Seidl R, Bogdanova N, Röpke A, Wieacker P, Am Zehnhoff-Dinnesen A
Brain Lang 2016 Aug;159:102-8. Epub 2016 Jul 4 doi: 10.1016/j.bandl.2016.06.005. PMID: 27388785
Early language delay and specific language impairment.
Moyle J, Stokes SF, Klee T
Dev Disabil Res Rev 2011;17(2):160-9. doi: 10.1002/ddrr.1110. PMID: 23362035
Childhood aphasias.
Martins IP
Clin Neurosci 1997;4(2):73-7. PMID: 9059756

Recent systematic reviews

Audiovisual multisensory integration in individuals with reading and language impairments: A systematic review and meta-analysis.
Pulliam G, Feldman JI, Woynaroski TG
Neurosci Biobehav Rev 2023 Jun;149:105130. Epub 2023 Mar 17 doi: 10.1016/j.neubiorev.2023.105130. PMID: 36933815Free PMC Article
Procedural learning across the lifespan: A systematic review with implications for atypical development.
Zwart FS, Vissers CTWM, Kessels RPC, Maes JHR
J Neuropsychol 2019 Jun;13(2):149-182. Epub 2017 Oct 8 doi: 10.1111/jnp.12139. PMID: 28990357
Case History Risk Factors for Specific Language Impairment: A Systematic Review and Meta-Analysis.
Rudolph JM
Am J Speech Lang Pathol 2017 Aug 15;26(3):991-1010. doi: 10.1044/2016_AJSLP-15-0181. PMID: 28672377
Theory of Mind in Children With Specific Language Impairment: A Systematic Review and Meta-Analysis.
Nilsson KK, de López KJ
Child Dev 2016 Jan-Feb;87(1):143-53. Epub 2015 Nov 19 doi: 10.1111/cdev.12462. PMID: 26582261
Population-based screening of children for specific speech and language impairment in Germany: a systematic review.
Kasper J, Kreis J, Scheibler F, Möller D, Skipka G, Lange S, von dem Knesebeck O
Folia Phoniatr Logop 2011;63(5):247-63. Epub 2011 Feb 8 doi: 10.1159/000321000. PMID: 21304231

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