U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Meningoencephalitis

MedGen UID:
6301
Concept ID:
C0025309
Disease or Syndrome
Synonyms: Cerebromeningitides; Cerebromeningitis; Encephalomeningitides; Encephalomeningitis; Meningoencephalitides
SNOMED CT: Meningoencephalitis (7125002)
 
Monarch Initiative: MONDO:0005845

Definition

Inflammation of the meninges and brain, generally secondary to an infectious cause. Pathogens may be bacterial, viral, fungal, or protozoan. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Grace E, Asbill S, Virga K
Antimicrob Agents Chemother 2015 Nov;59(11):6677-81. Epub 2015 Aug 10 doi: 10.1128/AAC.01293-15. PMID: 26259797Free PMC Article
Perfect JR, Dismukes WE, Dromer F, Goldman DL, Graybill JR, Hamill RJ, Harrison TS, Larsen RA, Lortholary O, Nguyen MH, Pappas PG, Powderly WG, Singh N, Sobel JD, Sorrell TC
Clin Infect Dis 2010 Feb 1;50(3):291-322. doi: 10.1086/649858. PMID: 20047480Free PMC Article

Recent clinical studies

Etiology

Succar EF, Turner JH, Chandra RK
Int Forum Allergy Rhinol 2019 May;9(S1):S4-S8. doi: 10.1002/alr.22330. PMID: 31087631
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ
Infect Dis Clin North Am 2018 Mar;32(1):145-162. Epub 2017 Dec 8 doi: 10.1016/j.idc.2017.10.007. PMID: 29224854Free PMC Article
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707
Esposito S, Rahamat-Langendoen J, Ascolese B, Senatore L, Castellazzi L, Niesters HG
J Clin Virol 2014 Jun;60(2):84-9. Epub 2014 Mar 13 doi: 10.1016/j.jcv.2014.03.003. PMID: 24690382
Kaiser R
Infect Dis Clin North Am 2008 Sep;22(3):561-75, x. doi: 10.1016/j.idc.2008.03.013. PMID: 18755391

Diagnosis

Thy M, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Curr Opin Crit Care 2023 Oct 1;29(5):415-422. Epub 2023 Aug 9 doi: 10.1097/MCC.0000000000001087. PMID: 37641514
Rojo JU, Rajendran R, Salazar JH
Lab Med 2023 Sep 5;54(5):e124-e132. doi: 10.1093/labmed/lmac158. PMID: 36638160
Ramachandran PS, Wilson MR
Neurol Clin 2018 Nov;36(4):687-703. doi: 10.1016/j.ncl.2018.07.004. PMID: 30366549Free PMC Article
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Therapy

Kidd DP
Pract Neurol 2023 Oct;23(5):386-400. Epub 2023 Sep 29 doi: 10.1136/pn-2023-003875. PMID: 37775123
Caffes N, Hendricks K, Bradley JS, Twenhafel NA, Simard JM
Clin Infect Dis 2022 Oct 17;75(Suppl 3):S451-S458. doi: 10.1093/cid/ciac521. PMID: 36251558Free PMC Article
Stott KE, Loyse A, Jarvis JN, Alufandika M, Harrison TS, Mwandumba HC, Day JN, Lalloo DG, Bicanic T, Perfect JR, Hope W
Lancet Infect Dis 2021 Sep;21(9):e259-e271. Epub 2021 Apr 16 doi: 10.1016/S1473-3099(20)30771-4. PMID: 33872594
Cheong TZ, Davies RP
Ophthalmic Plast Reconstr Surg 2019 Mar/Apr;35(2):e47-e49. doi: 10.1097/IOP.0000000000001324. PMID: 30730432
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042

Prognosis

Rojo JU, Rajendran R, Salazar JH
Lab Med 2023 Sep 5;54(5):e124-e132. doi: 10.1093/labmed/lmac158. PMID: 36638160
Carod-Artal FJ
Expert Rev Anti Infect Ther 2018 May;16(5):399-410. Epub 2018 Apr 26 doi: 10.1080/14787210.2018.1466702. PMID: 29668332
Nascimento OJM, da Silva IRF
Curr Opin Neurol 2017 Oct;30(5):500-507. doi: 10.1097/WCO.0000000000000471. PMID: 28617719
Britton PN, Eastwood K, Paterson B, Durrheim DN, Dale RC, Cheng AC, Kenedi C, Brew BJ, Burrow J, Nagree Y, Leman P, Smith DW, Read K, Booy R, Jones CA; Australasian Society of Infectious Diseases (ASID); Australasian College of Emergency Medicine (ACEM); Australian and New Zealand Association of Neurologists (ANZAN); Public Health Association of Australia (PHAA)
Intern Med J 2015 May;45(5):563-76. doi: 10.1111/imj.12749. PMID: 25955462
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Clinical prediction guides

Wang YH, Zhang YG
Immunobiology 2018 Mar;223(3):288-293. Epub 2017 Oct 16 doi: 10.1016/j.imbio.2017.10.038. PMID: 29070439
Charlier C, Perrodeau É, Leclercq A, Cazenave B, Pilmis B, Henry B, Lopes A, Maury MM, Moura A, Goffinet F, Dieye HB, Thouvenot P, Ungeheuer MN, Tourdjman M, Goulet V, de Valk H, Lortholary O, Ravaud P, Lecuit M; MONALISA study group
Lancet Infect Dis 2017 May;17(5):510-519. Epub 2017 Jan 28 doi: 10.1016/S1473-3099(16)30521-7. PMID: 28139432
Filigheddu MT, Górgolas M, Ramos JM
Med Clin (Barc) 2017 Feb 9;148(3):125-131. Epub 2016 Dec 16 doi: 10.1016/j.medcli.2016.10.038. PMID: 27993415
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707
Opperdoes FR, De Jonckheere JF, Tielens AG
Int J Parasitol 2011 Aug 1;41(9):915-24. Epub 2011 Jun 16 doi: 10.1016/j.ijpara.2011.04.004. PMID: 21722646

Recent systematic reviews

Zhang M, Wang H, Tang J, He Y, Xiong T, Li W, Qu Y, Mu D
BMC Pediatr 2021 Mar 15;21(1):127. doi: 10.1186/s12887-021-02599-y. PMID: 33722228Free PMC Article
Velasco R, Villagrán M, Jové M, Simó M, Vilariño N, Alemany M, Palmero R, Martínez-Villacampa MM, Nadal E, Bruna J
JAMA Neurol 2021 Jul 1;78(7):864-873. doi: 10.1001/jamaneurol.2021.0249. PMID: 33720308
Meliou M, Mavridis IN, Pyrgelis ES, Agapiou E
Acta Parasitol 2020 Jun;65(2):291-299. Epub 2020 Jan 20 doi: 10.2478/s11686-019-00166-1. PMID: 31960218
Córdova E, Maiolo E, Corti M, Orduña T
Neurol Res 2010 Apr;32(3):238-44. doi: 10.1179/016164110X12644252260637. PMID: 20406601
Rafailidis PI, Mourtzoukou EG, Varbobitis IC, Falagas ME
Virol J 2008 Mar 27;5:47. doi: 10.1186/1743-422X-5-47. PMID: 18371229Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...