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Maternal Transmission

MedGen UID:
66943
•Concept ID:
C0242648
•
Pathologic Function
Synonyms: Infection Transmission, Vertical; Infectious Disease Transmission, Vertical; Pathogen Transmission, Vertical; Transmission, Vertical Infection; Transmission, Vertical Pathogen; Vertical Infection Transmission; Vertical Infectious Disease Transmission; Vertical Pathogen Transmission; Vertical Transmission of Infectious Disease

Definition

The passage of a substance or infectious agent from the mother to the fetus or newborn. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMaternal Transmission

Professional guidelines

PubMed

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin, Number 220.
Obstet Gynecol 2020 May;135(5):e193-e202. doi: 10.1097/AOG.0000000000003840. PMID: 32332414
Treatment strategies for Leber hereditary optic neuropathy.
Jurkute N, Harvey J, Yu-Wai-Man P
Curr Opin Neurol 2019 Feb;32(1):99-104. doi: 10.1097/WCO.0000000000000646. PMID: 30516647
Genotype and phenotype correlations in 417 children with congenital hyperinsulinism.
Snider KE, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Stanley CA, Ganguly A
J Clin Endocrinol Metab 2013 Feb;98(2):E355-63. Epub 2012 Dec 28 doi: 10.1210/jc.2012-2169. PMID: 23275527Free PMC Article

Recent clinical studies

Etiology

Viral hepatitis in pregnancy.
Shata MTM, Hetta HF, Sharma Y, Sherman KE
J Viral Hepat 2022 Oct;29(10):844-861. Epub 2022 Jul 7 doi: 10.1111/jvh.13725. PMID: 35748741Free PMC Article
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin, Number 220.
Obstet Gynecol 2020 May;135(5):e193-e202. doi: 10.1097/AOG.0000000000003840. PMID: 32332414
Excess of rare, inherited truncating mutations in autism.
Krumm N, Turner TN, Baker C, Vives L, Mohajeri K, Witherspoon K, Raja A, Coe BP, Stessman HA, He ZX, Leal SM, Bernier R, Eichler EE
Nat Genet 2015 Jun;47(6):582-8. Epub 2015 May 11 doi: 10.1038/ng.3303. PMID: 25961944Free PMC Article
The inheritance of obesity.
Savona-Ventura C, Savona-Ventura S
Best Pract Res Clin Obstet Gynaecol 2015 Apr;29(3):300-8. Epub 2014 Oct 25 doi: 10.1016/j.bpobgyn.2014.07.023. PMID: 25457854
Fragile X full mutation expansions are inhibited by one or more AGG interruptions in premutation carriers.
Nolin SL, Glicksman A, Ersalesi N, Dobkin C, Brown WT, Cao R, Blatt E, Sah S, Latham GJ, Hadd AG
Genet Med 2015 May;17(5):358-64. Epub 2014 Sep 11 doi: 10.1038/gim.2014.106. PMID: 25210937

Diagnosis

Clinical and Genetic Characterization of Familial Central Precocious Puberty.
Tinano FR, Canton APM, Montenegro LR, de Castro Leal A, Faria AG, Seraphim CE, Brauner R, Jorge AA, Mendonca BB, Argente J, Brito VN, Latronico AC
J Clin Endocrinol Metab 2023 Jun 16;108(7):1758-1767. doi: 10.1210/clinem/dgac763. PMID: 36611250
Zika & heart: A systematic review.
Scatularo CE, Ballesteros OA, Saldarriaga C, Mendoza I, Wyss F, Liprandi AS, Munera A, Liendro MC, Baranchuk A; Neglected Tropical Diseases and other Infectious Diseases affecting the Heart (NET-Heart project)
Trends Cardiovasc Med 2022 Jan;32(1):52-58. Epub 2020 Nov 18 doi: 10.1016/j.tcm.2020.11.003. PMID: 33220438
Mothers' and children's metacognitions and the development of childhood anxiety: a longitudinal investigation of transmission.
Walczak M, Reinholdt-Dunne ML, Normann N, Christiansen BM, Esbjørn BH
Eur Child Adolesc Psychiatry 2021 Mar;30(3):451-459. Epub 2020 Apr 18 doi: 10.1007/s00787-020-01531-6. PMID: 32303854
Fragile X full mutation expansions are inhibited by one or more AGG interruptions in premutation carriers.
Nolin SL, Glicksman A, Ersalesi N, Dobkin C, Brown WT, Cao R, Blatt E, Sah S, Latham GJ, Hadd AG
Genet Med 2015 May;17(5):358-64. Epub 2014 Sep 11 doi: 10.1038/gim.2014.106. PMID: 25210937
Genotype and phenotype correlations in 417 children with congenital hyperinsulinism.
Snider KE, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Stanley CA, Ganguly A
J Clin Endocrinol Metab 2013 Feb;98(2):E355-63. Epub 2012 Dec 28 doi: 10.1210/jc.2012-2169. PMID: 23275527Free PMC Article

Therapy

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin, Number 220.
Obstet Gynecol 2020 May;135(5):e193-e202. doi: 10.1097/AOG.0000000000003840. PMID: 32332414
Paternal or maternal history of cardiovascular disease and the risk of cardiovascular disease in offspring. A systematic review and meta-analysis.
Weijmans M, van der Graaf Y, Reitsma JB, Visseren FL
Int J Cardiol 2015 Jan 20;179:409-16. Epub 2014 Nov 5 doi: 10.1016/j.ijcard.2014.11.017. PMID: 25464496
Dementia prevention: shared questions for research and clinical management.
Robertson M, Brown E, Whalley L
Maturitas 2014 Feb;77(2):124-7. Epub 2013 Dec 4 doi: 10.1016/j.maturitas.2013.11.005. PMID: 24378185
Mitochondrial diseases: therapeutic approaches.
DiMauro S, Mancuso M
Biosci Rep 2007 Jun;27(1-3):125-37. doi: 10.1007/s10540-007-9041-4. PMID: 17486439
Mitochondrial encephalomyopathies: therapeutic approach.
Dimauro S, Mancuso M, Naini A
Ann N Y Acad Sci 2004 Apr;1011:232-45. doi: 10.1196/annals.1293.023. PMID: 15126300

Prognosis

Mothers' and children's metacognitions and the development of childhood anxiety: a longitudinal investigation of transmission.
Walczak M, Reinholdt-Dunne ML, Normann N, Christiansen BM, Esbjørn BH
Eur Child Adolesc Psychiatry 2021 Mar;30(3):451-459. Epub 2020 Apr 18 doi: 10.1007/s00787-020-01531-6. PMID: 32303854
Development of child immunity in the context of COVID-19 pandemic.
Kloc M, Ghobrial RM, Kuchar E, Lewicki S, Kubiak JZ
Clin Immunol 2020 Aug;217:108510. Epub 2020 Jun 13 doi: 10.1016/j.clim.2020.108510. PMID: 32544611Free PMC Article
Treatment strategies for Leber hereditary optic neuropathy.
Jurkute N, Harvey J, Yu-Wai-Man P
Curr Opin Neurol 2019 Feb;32(1):99-104. doi: 10.1097/WCO.0000000000000646. PMID: 30516647
Genotype and phenotype correlations in 417 children with congenital hyperinsulinism.
Snider KE, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Stanley CA, Ganguly A
J Clin Endocrinol Metab 2013 Feb;98(2):E355-63. Epub 2012 Dec 28 doi: 10.1210/jc.2012-2169. PMID: 23275527Free PMC Article
Is maternal transmission of coronary heart disease risk stronger than paternal transmission?
Kinra S, Davey Smith G, Okasha M, McCarron P, McEwen J
Heart 2003 Aug;89(8):834-8. doi: 10.1136/heart.89.8.834. PMID: 12860850Free PMC Article

Clinical prediction guides

Mothers' and children's metacognitions and the development of childhood anxiety: a longitudinal investigation of transmission.
Walczak M, Reinholdt-Dunne ML, Normann N, Christiansen BM, Esbjørn BH
Eur Child Adolesc Psychiatry 2021 Mar;30(3):451-459. Epub 2020 Apr 18 doi: 10.1007/s00787-020-01531-6. PMID: 32303854
Molecular genetics of congenital myotonic dystrophy.
Lanni S, Pearson CE
Neurobiol Dis 2019 Dec;132:104533. Epub 2019 Jul 19 doi: 10.1016/j.nbd.2019.104533. PMID: 31326502
Excess of rare, inherited truncating mutations in autism.
Krumm N, Turner TN, Baker C, Vives L, Mohajeri K, Witherspoon K, Raja A, Coe BP, Stessman HA, He ZX, Leal SM, Bernier R, Eichler EE
Nat Genet 2015 Jun;47(6):582-8. Epub 2015 May 11 doi: 10.1038/ng.3303. PMID: 25961944Free PMC Article
Fragile X full mutation expansions are inhibited by one or more AGG interruptions in premutation carriers.
Nolin SL, Glicksman A, Ersalesi N, Dobkin C, Brown WT, Cao R, Blatt E, Sah S, Latham GJ, Hadd AG
Genet Med 2015 May;17(5):358-64. Epub 2014 Sep 11 doi: 10.1038/gim.2014.106. PMID: 25210937
Genotype and phenotype correlations in 417 children with congenital hyperinsulinism.
Snider KE, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Stanley CA, Ganguly A
J Clin Endocrinol Metab 2013 Feb;98(2):E355-63. Epub 2012 Dec 28 doi: 10.1210/jc.2012-2169. PMID: 23275527Free PMC Article

Recent systematic reviews

A rapid systematic scoping review of research on the impacts of water contaminated by chemicals on very young children.
Shittu E, Lakhanpaul M, Vigurs C, Sarkar K, Koch M, Parikh P, Campos LC
Sci Total Environ 2023 Sep 15;891:164604. Epub 2023 Jun 2 doi: 10.1016/j.scitotenv.2023.164604. PMID: 37271388
Zika & heart: A systematic review.
Scatularo CE, Ballesteros OA, Saldarriaga C, Mendoza I, Wyss F, Liprandi AS, Munera A, Liendro MC, Baranchuk A; Neglected Tropical Diseases and other Infectious Diseases affecting the Heart (NET-Heart project)
Trends Cardiovasc Med 2022 Jan;32(1):52-58. Epub 2020 Nov 18 doi: 10.1016/j.tcm.2020.11.003. PMID: 33220438
Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis.
Walker KF, O'Donoghue K, Grace N, Dorling J, Comeau JL, Li W, Thornton JG
BJOG 2020 Oct;127(11):1324-1336. Epub 2020 Jul 22 doi: 10.1111/1471-0528.16362. PMID: 32531146Free PMC Article
Safe management of expressed breast milk: A systematic review.
Peters MD, McArthur A, Munn Z
Women Birth 2016 Dec;29(6):473-481. Epub 2016 Jun 16 doi: 10.1016/j.wombi.2016.05.007. PMID: 27318564
Paternal or maternal history of cardiovascular disease and the risk of cardiovascular disease in offspring. A systematic review and meta-analysis.
Weijmans M, van der Graaf Y, Reitsma JB, Visseren FL
Int J Cardiol 2015 Jan 20;179:409-16. Epub 2014 Nov 5 doi: 10.1016/j.ijcard.2014.11.017. PMID: 25464496

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