U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coldness

MedGen UID:
678345
•Concept ID:
C0812387
•
Finding
Synonyms: Cold skin temperature; Cool skin; Cool skin temperature; Coolness to palpation
SNOMED CT: Cool skin (427733005)
 
HPO: HP:0033850

Definition

Relative coldness of a body part to palpitation, often acccompanied by feelings of coldness. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColdness

Professional guidelines

PubMed

Anti-Tumor Immunity and Preoperative Radiovaccination: Emerging New Concepts in the Treatment of Breast Cancer.
Koukourakis IM, Papadimitriou M, Desse D, Zygogianni A, Papadimitriou C
Int J Mol Sci 2023 May 26;24(11) doi: 10.3390/ijms24119310. PMID: 37298262Free PMC Article
Green Urine in Traditional Persian Medicine: Differential Diagnosis and Clinical Relevance.
Kolouri S, Daneshfard B, Jaladat AM, Tafazoli V
J Evid Based Complementary Altern Med 2017 Apr;22(2):232-236. Epub 2016 Jul 8 doi: 10.1177/2156587216641828. PMID: 27103627Free PMC Article
Painful diabetic neuropathy: diagnosis and management.
Hartemann A, Attal N, Bouhassira D, Dumont I, Gin H, Jeanne S, Said G, Richard JL; Working Group on the Diabetic Foot from the French-speaking Society of Diabetology
Diabetes Metab 2011 Nov;37(5):377-88. Epub 2011 Aug 4 doi: 10.1016/j.diabet.2011.06.003. PMID: 21820345

Recent clinical studies

Etiology

Personal and family perfectionism among Asian and Latinx youth.
Fung J, Cai G, Wang K
Cultur Divers Ethnic Minor Psychol 2023 Apr;29(2):235-246. Epub 2022 Aug 18 doi: 10.1037/cdp0000555. PMID: 35980690
American prejudice during the COVID-19 pandemic.
Huber C, Brietzke S, Inagaki TK, Meyer ML
Sci Rep 2022 Dec 24;12(1):22278. doi: 10.1038/s41598-022-26163-5. PMID: 36566280Free PMC Article
Is there an association between caregiver antipathy and psychosis? A systematic review.
Barnes GL, Garety PA, Emsley R, Jameel L, Hardy A
Psychol Psychother 2021 Sep;94(3):798-821. Epub 2021 Feb 17 doi: 10.1111/papt.12328. PMID: 33595172
Understanding COVID-19 in the light of epidemic disease described in Unani medicine.
Alam MA, Quamri MA, Sofi G, Ayman U, Ansari S, Ahad M
Drug Metab Pers Ther 2020 Sep 24;35(4) doi: 10.1515/dmpt-2020-0136. PMID: 34704695
Buerger's disease.
Dargon PT, Landry GJ
Ann Vasc Surg 2012 Aug;26(6):871-80. Epub 2012 Jan 27 doi: 10.1016/j.avsg.2011.11.005. PMID: 22284771

Diagnosis

Acral coldness - severely reduced blood flow to fingers and toes.
Bergersen TK, Walløe L
Handb Clin Neurol 2018;157:677-685. doi: 10.1016/B978-0-444-64074-1.00040-9. PMID: 30459032
Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial.
Kleckner IR, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, Fung C, Janelsins MC, Asare M, Lin PJ, Reddy PS, Giguere J, Berenberg J, Kesler SR, Mustian KM
Support Care Cancer 2018 Apr;26(4):1019-1028. Epub 2017 Dec 14 doi: 10.1007/s00520-017-4013-0. PMID: 29243164Free PMC Article
Small fiber neuropathy: Getting bigger!
Chan AC, Wilder-Smith EP
Muscle Nerve 2016 May;53(5):671-82. Epub 2016 Mar 12 doi: 10.1002/mus.25082. PMID: 26872938
The Nadja case.
Bogousslavsky J
Front Neurol Neurosci 2013;31:44-51. Epub 2013 Mar 5 doi: 10.1159/000343234. PMID: 23485891
Buerger's disease.
Dargon PT, Landry GJ
Ann Vasc Surg 2012 Aug;26(6):871-80. Epub 2012 Jan 27 doi: 10.1016/j.avsg.2011.11.005. PMID: 22284771

Therapy

Severe night sweating treated by oxybutynin.
Dias L, Martinot C, Vaillant G, Arnulf I
J Clin Sleep Med 2024 Jan 1;20(1):169-172. doi: 10.5664/jcsm.10842. PMID: 38163944Free PMC Article
Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial.
Kleckner IR, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, Fung C, Janelsins MC, Asare M, Lin PJ, Reddy PS, Giguere J, Berenberg J, Kesler SR, Mustian KM
Support Care Cancer 2018 Apr;26(4):1019-1028. Epub 2017 Dec 14 doi: 10.1007/s00520-017-4013-0. PMID: 29243164Free PMC Article
Safety of Oral Propranolol for the Treatment of Infantile Hemangioma: A Systematic Review.
Léaute-Labrèze C, Boccara O, Degrugillier-Chopinet C, Mazereeuw-Hautier J, Prey S, Lebbé G, Gautier S, Ortis V, Lafon M, Montagne A, Delarue A, Voisard JJ
Pediatrics 2016 Oct;138(4) doi: 10.1542/peds.2016-0353. PMID: 27688361
Small fiber neuropathy: Getting bigger!
Chan AC, Wilder-Smith EP
Muscle Nerve 2016 May;53(5):671-82. Epub 2016 Mar 12 doi: 10.1002/mus.25082. PMID: 26872938
Buerger's disease.
Dargon PT, Landry GJ
Ann Vasc Surg 2012 Aug;26(6):871-80. Epub 2012 Jan 27 doi: 10.1016/j.avsg.2011.11.005. PMID: 22284771

Prognosis

Understanding COVID-19 in the light of epidemic disease described in Unani medicine.
Alam MA, Quamri MA, Sofi G, Ayman U, Ansari S, Ahad M
Drug Metab Pers Ther 2020 Sep 24;35(4) doi: 10.1515/dmpt-2020-0136. PMID: 34704695
Accelerated Atherogenicity in Tangier Disease.
Muratsu J, Koseki M, Masuda D, Yasuga Y, Tomoyama S, Ataka K, Yagi Y, Nakagawa A, Hamada H, Fujita S, Hattori H, Ohama T, Nishida M, Hiraoka H, Matsuzawa Y, Yamashita S
J Atheroscler Thromb 2018 Oct 1;25(10):1076-1085. Epub 2018 Mar 20 doi: 10.5551/jat.43257. PMID: 29563393Free PMC Article
Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial.
Kleckner IR, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, Fung C, Janelsins MC, Asare M, Lin PJ, Reddy PS, Giguere J, Berenberg J, Kesler SR, Mustian KM
Support Care Cancer 2018 Apr;26(4):1019-1028. Epub 2017 Dec 14 doi: 10.1007/s00520-017-4013-0. PMID: 29243164Free PMC Article
Algodystrophy in children and adolescents: a review.
Zyluk A
Pol Orthop Traumatol 2013 Dec 18;78:265-71. PMID: 24351874
Synophrys.
Möhrenschlager M, Lauenstein M, Ring J, Steiner C
Eur J Med Genet 2010 Jul-Aug;53(4):225-6. Epub 2010 Feb 10 doi: 10.1016/j.ejmg.2010.02.001. PMID: 20152950

Clinical prediction guides

Profiles of self-compassion and psychological outcomes in cancer patients.
Wei L, Xie J, Wu L, Yao J, Zhu L, Liu A
Psychooncology 2023 Jan;32(1):25-33. Epub 2022 Mar 31 doi: 10.1002/pon.5931. PMID: 35334138
Self-criticism, self-compassion, and perceived health: moderating effect of ethnicity.
Boyraz G, Legros DN, Berger WB
J Gen Psychol 2021 Apr-Jun;148(2):149-167. Epub 2020 Apr 3 doi: 10.1080/00221309.2020.1746232. PMID: 32241224
Acral coldness - severely reduced blood flow to fingers and toes.
Bergersen TK, Walløe L
Handb Clin Neurol 2018;157:677-685. doi: 10.1016/B978-0-444-64074-1.00040-9. PMID: 30459032
Accelerated Atherogenicity in Tangier Disease.
Muratsu J, Koseki M, Masuda D, Yasuga Y, Tomoyama S, Ataka K, Yagi Y, Nakagawa A, Hamada H, Fujita S, Hattori H, Ohama T, Nishida M, Hiraoka H, Matsuzawa Y, Yamashita S
J Atheroscler Thromb 2018 Oct 1;25(10):1076-1085. Epub 2018 Mar 20 doi: 10.5551/jat.43257. PMID: 29563393Free PMC Article
Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial.
Kleckner IR, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, Fung C, Janelsins MC, Asare M, Lin PJ, Reddy PS, Giguere J, Berenberg J, Kesler SR, Mustian KM
Support Care Cancer 2018 Apr;26(4):1019-1028. Epub 2017 Dec 14 doi: 10.1007/s00520-017-4013-0. PMID: 29243164Free PMC Article

Recent systematic reviews

Is there an association between caregiver antipathy and psychosis? A systematic review.
Barnes GL, Garety PA, Emsley R, Jameel L, Hardy A
Psychol Psychother 2021 Sep;94(3):798-821. Epub 2021 Feb 17 doi: 10.1111/papt.12328. PMID: 33595172
Herbal Medicines for Cold Hypersensitivity in the Hands and Feet: A Systematic Review and Meta-Analysis.
Yu JS, Lee D, Hyun D, Chang SJ
J Altern Complement Med 2018 Dec;24(12):1150-1158. Epub 2018 Jul 11 doi: 10.1089/acm.2018.0009. PMID: 29993255Free PMC Article
Safety of Oral Propranolol for the Treatment of Infantile Hemangioma: A Systematic Review.
Léaute-Labrèze C, Boccara O, Degrugillier-Chopinet C, Mazereeuw-Hautier J, Prey S, Lebbé G, Gautier S, Ortis V, Lafon M, Montagne A, Delarue A, Voisard JJ
Pediatrics 2016 Oct;138(4) doi: 10.1542/peds.2016-0353. PMID: 27688361
The clinical features of hand-arm vibration syndrome in a warm environment--a review of the literature.
Su AT, Darus A, Bulgiba A, Maeda S, Miyashita K
J Occup Health 2012;54(5):349-60. Epub 2012 Aug 2 doi: 10.1539/joh.12-0089-ra. PMID: 22863899
Risk factors for musculoskeletal disorders among farm owners and farm workers: a systematic review.
Osborne A, Blake C, Fullen BM, Meredith D, Phelan J, McNamara J, Cunningham C
Am J Ind Med 2012 Apr;55(4):376-89. Epub 2011 Dec 27 doi: 10.1002/ajim.22001. PMID: 22213399

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...