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Moderately Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements

MedGen UID:
690104
•Concept ID:
C1266107
•
Neoplastic Process
Synonyms: Intermediate Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements; Sertoli-Leydig cell tumor, intermediate differentiation, with heterologous elements; Sertoli-Leydig cell tumor, moderately differentiated, with heterologous elements; Sertoli-Leydig cell tumor, retiform, with heterologous elements
SNOMED CT: Sertoli-Leydig cell tumor, retiform, with heterologous elements (128725005); Sertoli-Leydig cell tumor, intermediate differentiation, with heterologous elements (128725005); Sertoli-Leydig cell tumor, moderately differentiated, with heterologous elements (128725005)

Definition

An ovarian Sertoli-Leydig cell tumor of intermediate differentiation, characterized by the presence of a heterologous component, usually consisting of cartilage, skeletal muscle, or rhabdomyosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVModerately Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements

Recent clinical studies

Etiology

Sertoli-Leydig cell tumor of ovary in children: A report of two cases, including retiform variant.
Sarkar P, Sengupta M, Chatterjee U, Ghosh D
Indian J Pathol Microbiol 2021 Jul-Sep;64(3):559-562. doi: 10.4103/IJPM.IJPM_443_20. PMID: 34341273

Diagnosis

Sertoli-Leydig cell tumor of ovary in children: A report of two cases, including retiform variant.
Sarkar P, Sengupta M, Chatterjee U, Ghosh D
Indian J Pathol Microbiol 2021 Jul-Sep;64(3):559-562. doi: 10.4103/IJPM.IJPM_443_20. PMID: 34341273

Prognosis

Sertoli - Leydig cell tumor with retiform areas and overgrowth of rhabdomyosarcomatous elements: case report and literature review.
Burnik Papler T, Frković Grazio S, Kobal B
J Ovarian Res 2016 Jul 30;9(1):46. doi: 10.1186/s13048-016-0257-4. PMID: 27473538Free PMC Article

Clinical prediction guides

Sertoli - Leydig cell tumor with retiform areas and overgrowth of rhabdomyosarcomatous elements: case report and literature review.
Burnik Papler T, Frković Grazio S, Kobal B
J Ovarian Res 2016 Jul 30;9(1):46. doi: 10.1186/s13048-016-0257-4. PMID: 27473538Free PMC Article

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