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Family history

MedGen UID:
69143
•Concept ID:
C0241889
•
Finding
Synonym: Family history of clinical finding
SNOMED CT: Family history of clinical finding (416471007); Family medical history (416471007); Family history with explicit context (57177007); FH - family history (57177007); Family history of (57177007)
 
HPO: HP:0032316

Definition

Information about close relatives of an individual who is the proband of a study or who is being investigated with the goal of identifying a medical diagnosis. Usually, the family history includes information from three generations of relatives, including children, brothers and sisters, parents, aunts and uncles, nieces and nephews, grandparents, and cousins. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Family history

Professional guidelines

PubMed

Assessment of Cardiovascular Disease Risk: A 2022 Update.
Goldsborough E 3rd, Osuji N, Blaha MJ
Endocrinol Metab Clin North Am 2022 Sep;51(3):483-509. Epub 2022 Jul 4 doi: 10.1016/j.ecl.2022.02.005. PMID: 35963625
Glaucoma in Adults-Screening, Diagnosis, and Management: A Review.
Stein JD, Khawaja AP, Weizer JS
JAMA 2021 Jan 12;325(2):164-174. doi: 10.1001/jama.2020.21899. PMID: 33433580
ACG and CAG Clinical Guideline: Management of Dyspepsia.
Moayyedi P, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N
Am J Gastroenterol 2017 Jul;112(7):988-1013. Epub 2017 Jun 20 doi: 10.1038/ajg.2017.154. PMID: 28631728

Recent clinical studies

Etiology

Stuttering, family history and counselling: A contemporary database.
Darmody T, O'Brian S, Rogers K, Onslow M, Jacobs C, McEwen A, Lowe R, Packman A, Menzies R
J Fluency Disord 2022 Sep;73:105925. Epub 2022 Aug 13 doi: 10.1016/j.jfludis.2022.105925. PMID: 35998418
Family history and pelvic organ prolapse: a systematic review and meta-analysis.
Samimi P, Jones SH, Giri A
Int Urogynecol J 2021 Apr;32(4):759-774. Epub 2020 Oct 21 doi: 10.1007/s00192-020-04559-z. PMID: 33084962Free PMC Article
Meta-analysis of comorbid diabetes and family history of diabetes in non-affective psychosis.
Chung J, Miller BJ
Schizophr Res 2020 Feb;216:41-47. Epub 2019 Dec 2 doi: 10.1016/j.schres.2019.10.062. PMID: 31806529
Glaucoma history and risk factors.
McMonnies CW
J Optom 2017 Apr-Jun;10(2):71-78. Epub 2016 Mar 23 doi: 10.1016/j.optom.2016.02.003. PMID: 27025415Free PMC Article
Family history and the natural history of colorectal cancer: systematic review.
Henrikson NB, Webber EM, Goddard KA, Scrol A, Piper M, Williams MS, Zallen DT, Calonge N, Ganiats TG, Janssens AC, Zauber A, Lansdorp-Vogelaar I, van Ballegooijen M, Whitlock EP
Genet Med 2015 Sep;17(9):702-12. Epub 2015 Jan 15 doi: 10.1038/gim.2014.188. PMID: 25590981Free PMC Article

Diagnosis

Essential Pieces to the Genetics Puzzle: Family History and Dysmorphology Exam.
Tam A
Pediatr Clin North Am 2023 Oct;70(5):1047-1056. Epub 2023 Jul 1 doi: 10.1016/j.pcl.2023.05.012. PMID: 37704346
High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank.
Sproviero W, Winchester L, Newby D, Fernandes M, Shi L, Goodday SM, Prats-Uribe A, Alhambra DP, Buckley NJ, Nevado-Holgado AJ
Biol Psychiatry 2021 Apr 15;89(8):817-824. Epub 2020 Dec 27 doi: 10.1016/j.biopsych.2020.12.015. PMID: 33766239
Cholesteatoma and family history: An international survey.
Collins R, Ta NH, Jennings BA, Prinsley P, Philpott CM, Steel N, Clark A
Clin Otolaryngol 2020 Jul;45(4):500-505. Epub 2020 Apr 23 doi: 10.1111/coa.13544. PMID: 32271986
Glaucoma history and risk factors.
McMonnies CW
J Optom 2017 Apr-Jun;10(2):71-78. Epub 2016 Mar 23 doi: 10.1016/j.optom.2016.02.003. PMID: 27025415Free PMC Article
Family history and the natural history of colorectal cancer: systematic review.
Henrikson NB, Webber EM, Goddard KA, Scrol A, Piper M, Williams MS, Zallen DT, Calonge N, Ganiats TG, Janssens AC, Zauber A, Lansdorp-Vogelaar I, van Ballegooijen M, Whitlock EP
Genet Med 2015 Sep;17(9):702-12. Epub 2015 Jan 15 doi: 10.1038/gim.2014.188. PMID: 25590981Free PMC Article

Therapy

Disease-modifying therapies in amyotrophic lateral sclerosis.
Chiò A, Mazzini L, Mora G
Neuropharmacology 2020 May 1;167:107986. Epub 2020 Feb 3 doi: 10.1016/j.neuropharm.2020.107986. PMID: 32062193
SEOM clinical guidelines in hereditary breast and ovarian cancer (2019).
González-Santiago S, Ramón Y Cajal T, Aguirre E, Alés-Martínez JE, Andrés R, Balmaña J, Graña B, Herrero A, Llort G, González-Del-Alba A; SEOM Hereditary Cancer Working Group
Clin Transl Oncol 2020 Feb;22(2):193-200. Epub 2019 Dec 30 doi: 10.1007/s12094-019-02262-0. PMID: 31889241
Early-onset diabetes: an epidemic in China.
Pan J, Jia W
Front Med 2018 Dec;12(6):624-633. Epub 2018 Nov 5 doi: 10.1007/s11684-018-0669-1. PMID: 30393830
Dyslipidemia in systemic lupus erythematosus.
Szabó MZ, Szodoray P, Kiss E
Immunol Res 2017 Apr;65(2):543-550. doi: 10.1007/s12026-016-8892-9. PMID: 28168401
Human hallucinogen research: guidelines for safety.
Johnson M, Richards W, Griffiths R
J Psychopharmacol 2008 Aug;22(6):603-20. Epub 2008 Jul 1 doi: 10.1177/0269881108093587. PMID: 18593734Free PMC Article

Prognosis

Cancer incidence, patterns, and genotype-phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study.
de Andrade KC, Khincha PP, Hatton JN, Frone MN, Wegman-Ostrosky T, Mai PL, Best AF, Savage SA
Lancet Oncol 2021 Dec;22(12):1787-1798. Epub 2021 Nov 12 doi: 10.1016/S1470-2045(21)00580-5. PMID: 34780712Free PMC Article
Cervical Cancer Prevalence, Incidence and Mortality in Low and Middle Income Countries: A Systematic Review.
Shrestha AD, Neupane D, Vedsted P, Kallestrup P
Asian Pac J Cancer Prev 2018 Feb 26;19(2):319-324. doi: 10.22034/APJCP.2018.19.2.319. PMID: 29479954Free PMC Article
Predicting Coronary Heart Disease and Stroke: The FINRISK Calculator.
Vartiainen E, Laatikainen T, Peltonen M, Puska P
Glob Heart 2016 Jun;11(2):213-6. doi: 10.1016/j.gheart.2016.04.007. PMID: 27242089
Epidemiology of stomach cancer.
Brenner H, Rothenbacher D, Arndt V
Methods Mol Biol 2009;472:467-77. doi: 10.1007/978-1-60327-492-0_23. PMID: 19107449
Endometrial cancer.
Sorosky JI
Obstet Gynecol 2008 Feb;111(2 Pt 1):436-47. doi: 10.1097/AOG.0b013e318162f690. PMID: 18238985

Clinical prediction guides

Development and validation of a nomogram to better predict hypertension based on a 10-year retrospective cohort study in China.
Deng X, Hou H, Wang X, Li Q, Li X, Yang Z, Wu H
Elife 2021 May 28;10 doi: 10.7554/eLife.66419. PMID: 34047697Free PMC Article
Moderators and predictors of response to cognitive behaviour therapy for pediatric obsessive-compulsive disorder: A systematic review.
Turner C, O'Gorman B, Nair A, O'Kearney R
Psychiatry Res 2018 Mar;261:50-60. Epub 2017 Dec 20 doi: 10.1016/j.psychres.2017.12.034. PMID: 29287236
Book: Genetics for obstetricians and gynaecologists: Chapter: Genetic markers on ultrasound scan.
Sivanathan J, Thilaganathan B
Best Pract Res Clin Obstet Gynaecol 2017 Jul;42:64-85. Epub 2017 Mar 21 doi: 10.1016/j.bpobgyn.2017.03.005. PMID: 28456373
Instruments that prospectively predict bipolar disorder - A systematic review.
Ratheesh A, Berk M, Davey CG, McGorry PD, Cotton SM
J Affect Disord 2015 Jul 1;179:65-73. Epub 2015 Mar 21 doi: 10.1016/j.jad.2015.03.025. PMID: 25845751
Predictors of posttraumatic stress disorder and symptoms in adults: a meta-analysis.
Ozer EJ, Best SR, Lipsey TL, Weiss DS
Psychol Bull 2003 Jan;129(1):52-73. doi: 10.1037/0033-2909.129.1.52. PMID: 12555794

Recent systematic reviews

Thrombophilia Testing - a Systematic Review.
Asmis L, Hellstern P
Clin Lab 2023 Apr 1;69(4) doi: 10.7754/Clin.Lab.2022.220817. PMID: 37057948
Breastfeeding and Reduced Risk of Breast Cancer: A Systematic Review and Meta-Analysis.
Qiu R, Zhong Y, Hu M, Wu B
Comput Math Methods Med 2022;2022:8500910. Epub 2022 Jan 28 doi: 10.1155/2022/8500910. PMID: 35126640Free PMC Article
Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.
Maron BJ, Desai MY, Nishimura RA, Spirito P, Rakowski H, Towbin JA, Rowin EJ, Maron MS, Sherrid MV
J Am Coll Cardiol 2022 Feb 1;79(4):372-389. doi: 10.1016/j.jacc.2021.12.002. PMID: 35086660
Systematic review of the epidemiology of acne vulgaris.
Heng AHS, Chew FT
Sci Rep 2020 Apr 1;10(1):5754. doi: 10.1038/s41598-020-62715-3. PMID: 32238884Free PMC Article
Epidemiology of acne vulgaris.
Bhate K, Williams HC
Br J Dermatol 2013 Mar;168(3):474-85. doi: 10.1111/bjd.12149. PMID: 23210645

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • MeSH
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    • PubMed
      Related literature resources in PubMed

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