U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chronic autoimmune hepatitis

MedGen UID:
69144
Concept ID:
C0241910
Disease or Syndrome
Synonyms: Autoimmune Chronic Hepatitides; Autoimmune Chronic Hepatitis; Autoimmune Hepatitides; Autoimmune Hepatitis; Chronic Hepatitides, Autoimmune; Chronic Hepatitis, Autoimmune; Hepatitides, Autoimmune; Hepatitides, Autoimmune Chronic; Hepatitis, Autoimmune; Hepatitis, Autoimmune Chronic
SNOMED CT: Autoimmune chronic active hepatitis (197284004); Chronic autoimmune hepatitis (16098491000119109)

Definition

A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic autoimmune hepatitis
Follow this link to review classifications for Chronic autoimmune hepatitis in Orphanet.

Professional guidelines

PubMed

Díaz-González Á, Hernández-Guerra M, Pérez-Medrano I, Sapena V, Riveiro-Barciela M, Barreira-Díaz A, Gómez E, Morillas RM, Del Barrio M, Escudé L, Mateos B, Horta D, Gómez J, Conde I, Ferre-Aracil C, El Hajra I, Arencibía A, Zamora J, Fernández A, Salcedo M, Molina E, Soria A, Estévez P, López C, Álvarez-Navascúes C, García-Retortillo M, Crespo J, Londoño MC; ColHai Registry
Hepatology 2023 Apr 1;77(4):1095-1105. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000018. PMID: 36626622
Olivas I, Cobreros M, Londoño MC, Díaz-González Á
Gastroenterol Hepatol 2022 Aug-Sep;45(7):561-570. Epub 2021 Dec 16 doi: 10.1016/j.gastrohep.2021.11.012. PMID: 34923033
Dusheiko GM
Aliment Pharmacol Ther 1994 Apr;8(2):229-53. doi: 10.1111/j.1365-2036.1994.tb00283.x. PMID: 8038356

Recent clinical studies

Etiology

Díaz-González Á, Hernández-Guerra M, Pérez-Medrano I, Sapena V, Riveiro-Barciela M, Barreira-Díaz A, Gómez E, Morillas RM, Del Barrio M, Escudé L, Mateos B, Horta D, Gómez J, Conde I, Ferre-Aracil C, El Hajra I, Arencibía A, Zamora J, Fernández A, Salcedo M, Molina E, Soria A, Estévez P, López C, Álvarez-Navascúes C, García-Retortillo M, Crespo J, Londoño MC; ColHai Registry
Hepatology 2023 Apr 1;77(4):1095-1105. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000018. PMID: 36626622
Ferre-Aracil C, Riveiro-Barciela M, Trapero-Marugán M, Rodríguez-Perálvarez M, Llovet LP, Téllez L, Sánchez-Torrijos Y, Díaz-Fontenla F, Salcedo-Plaza M, Álvarez-López P, de la Mata M, Londoño MC, Bañares-Cañizares R, Calleja JL
Dig Dis Sci 2021 Aug;66(8):2826-2832. Epub 2020 Aug 29 doi: 10.1007/s10620-020-06569-9. PMID: 32860579
Yousefi A, Najafi M, Motamed F, Mahmoudi E, Bidoki AZ, Sadr M, Rahmani F, Farhmand F, Khodadad A, Fallahi G, Rezaei N
Ann Hepatol 2018 Oct 16;17(6):1021-1025. doi: 10.5604/01.3001.0012.7202. PMID: 30600293
Shen Y, Lu C, Men R, Liu J, Ye T, Yang L
Can J Gastroenterol Hepatol 2018;2018:3513206. Epub 2018 Mar 18 doi: 10.1155/2018/3513206. PMID: 29744332Free PMC Article
Koay LB, Tsai SL, Sun CS, Wu KT
Hepatogastroenterology 2008 Sep-Oct;55(86-87):1781-4. PMID: 19102393

Diagnosis

Ferre-Aracil C, Riveiro-Barciela M, Trapero-Marugán M, Rodríguez-Perálvarez M, Llovet LP, Téllez L, Sánchez-Torrijos Y, Díaz-Fontenla F, Salcedo-Plaza M, Álvarez-López P, de la Mata M, Londoño MC, Bañares-Cañizares R, Calleja JL
Dig Dis Sci 2021 Aug;66(8):2826-2832. Epub 2020 Aug 29 doi: 10.1007/s10620-020-06569-9. PMID: 32860579
Shen Y, Lu C, Men R, Liu J, Ye T, Yang L
Can J Gastroenterol Hepatol 2018;2018:3513206. Epub 2018 Mar 18 doi: 10.1155/2018/3513206. PMID: 29744332Free PMC Article
Zeman MV, Hirschfield GM
Can J Gastroenterol 2010 Apr;24(4):225-31. doi: 10.1155/2010/431913. PMID: 20431809Free PMC Article
Koay LB, Tsai SL, Sun CS, Wu KT
Hepatogastroenterology 2008 Sep-Oct;55(86-87):1781-4. PMID: 19102393
Theal RM, Scott K
Am Fam Physician 1996 May 1;53(6):2111-9. PMID: 8623723

Therapy

Díaz-González Á, Hernández-Guerra M, Pérez-Medrano I, Sapena V, Riveiro-Barciela M, Barreira-Díaz A, Gómez E, Morillas RM, Del Barrio M, Escudé L, Mateos B, Horta D, Gómez J, Conde I, Ferre-Aracil C, El Hajra I, Arencibía A, Zamora J, Fernández A, Salcedo M, Molina E, Soria A, Estévez P, López C, Álvarez-Navascúes C, García-Retortillo M, Crespo J, Londoño MC; ColHai Registry
Hepatology 2023 Apr 1;77(4):1095-1105. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000018. PMID: 36626622
Olivas I, Cobreros M, Londoño MC, Díaz-González Á
Gastroenterol Hepatol 2022 Aug-Sep;45(7):561-570. Epub 2021 Dec 16 doi: 10.1016/j.gastrohep.2021.11.012. PMID: 34923033
Ferre-Aracil C, Riveiro-Barciela M, Trapero-Marugán M, Rodríguez-Perálvarez M, Llovet LP, Téllez L, Sánchez-Torrijos Y, Díaz-Fontenla F, Salcedo-Plaza M, Álvarez-López P, de la Mata M, Londoño MC, Bañares-Cañizares R, Calleja JL
Dig Dis Sci 2021 Aug;66(8):2826-2832. Epub 2020 Aug 29 doi: 10.1007/s10620-020-06569-9. PMID: 32860579
Meunier L, Ursic-Bedoya J, Pageaux GP, Larrey D
Liver Int 2018 Jun;38(6):995-999. Epub 2018 Mar 31 doi: 10.1111/liv.13737. PMID: 29532602
Hardtke-Wolenski M, Fischer K, Noyan F, Schlue J, Falk CS, Stahlhut M, Woller N, Kuehnel F, Taubert R, Manns MP, Jaeckel E
Hepatology 2013 Aug;58(2):718-28. Epub 2013 Jul 1 doi: 10.1002/hep.26380. PMID: 23475565

Prognosis

Calisti G, Irish DN, Ijaz S, Tedder RS, Moore K
Ann Hepatol 2017 Jan-Feb 2017;16(1):160-163. doi: 10.5604/16652681.1226952. PMID: 28051806
Yüksel M, Laukens D, Heindryckx F, Van Vlierberghe H, Geerts A, Wong FS, Wen L, Colle I
Int J Exp Pathol 2014 Oct;95(5):309-20. Epub 2014 Aug 12 doi: 10.1111/iep.12090. PMID: 25112417Free PMC Article
Núñez-Martínez O, De la Cruz G, Salcedo M, Molina J, De Diego A, Ripoll C, Calleja J, Alvarez E, Clemente G
Transplant Proc 2003 Aug;35(5):1857-8. doi: 10.1016/s0041-1345(03)00591-8. PMID: 12962824
Balakrishnan C, Mangat G, Kalke S, Desai D, Joshi A, Deshpande RB, Joshi VR
J Assoc Physicians India 1998 May;46(5):431-5. PMID: 11273283
Burgart LJ, Batts KP, Ludwig J, Nikias GA, Czaja AJ
Am J Surg Pathol 1995 Jun;19(6):699-708. doi: 10.1097/00000478-199506000-00010. PMID: 7755156

Clinical prediction guides

Díaz-González Á, Hernández-Guerra M, Pérez-Medrano I, Sapena V, Riveiro-Barciela M, Barreira-Díaz A, Gómez E, Morillas RM, Del Barrio M, Escudé L, Mateos B, Horta D, Gómez J, Conde I, Ferre-Aracil C, El Hajra I, Arencibía A, Zamora J, Fernández A, Salcedo M, Molina E, Soria A, Estévez P, López C, Álvarez-Navascúes C, García-Retortillo M, Crespo J, Londoño MC; ColHai Registry
Hepatology 2023 Apr 1;77(4):1095-1105. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000018. PMID: 36626622
Shen Y, Lu C, Men R, Liu J, Ye T, Yang L
Can J Gastroenterol Hepatol 2018;2018:3513206. Epub 2018 Mar 18 doi: 10.1155/2018/3513206. PMID: 29744332Free PMC Article
Meunier L, Ursic-Bedoya J, Pageaux GP, Larrey D
Liver Int 2018 Jun;38(6):995-999. Epub 2018 Mar 31 doi: 10.1111/liv.13737. PMID: 29532602
Núñez-Martínez O, De la Cruz G, Salcedo M, Molina J, De Diego A, Ripoll C, Calleja J, Alvarez E, Clemente G
Transplant Proc 2003 Aug;35(5):1857-8. doi: 10.1016/s0041-1345(03)00591-8. PMID: 12962824
Theal RM, Scott K
Am Fam Physician 1996 May 1;53(6):2111-9. PMID: 8623723

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...