U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Systemic onset juvenile chronic arthritis

MedGen UID:
730498
Concept ID:
C1384600
Disease or Syndrome
Synonyms: Juvenile arthritis with systemic onset; Systemic Juvenile Idiopathic Arthritis; Systemic juvenile idiopathic arthritis; Systemic Onset Juvenile Idiopathic Arthritis; Systemic onset juvenile rheumatoid arthritis
SNOMED CT: Systemic onset juvenile rheumatoid arthritis (201796004); Systemic juvenile idiopathic arthritis (201796004); Systemic onset juvenile chronic arthritis (201796004); Juvenile arthritis with systemic onset (201796004)

Definition

A category of juvenile idiopathic arthritis defined by the presence of arthritis and high fevers, and accompanied by at least 2 of the following systemic features: lymphadenopathy, organomegaly, rash, or serositis. Macrophage activation syndrome is a well known complication. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSystemic onset juvenile chronic arthritis

Professional guidelines

PubMed

Adebajo AO, Hall MA
Br J Rheumatol 1998 Nov;37(11):1240-2. doi: 10.1093/rheumatology/37.11.1240. PMID: 9851278
Horneff G, Dirksen U, Schulze-Koops H, Emmrich F, Wahn V
Ann Rheum Dis 1995 Oct;54(10):846-9. doi: 10.1136/ard.54.10.846. PMID: 7492226Free PMC Article
Bardare M, Corona F, Ogliari MT, Cohen E
Clin Exp Rheumatol 1990 Jan-Feb;8(1):89-93. PMID: 1971780

Recent clinical studies

Etiology

Modesto C, Woo P, García-Consuegra J, Merino R, García-Granero M, Arnal C, Prieur AM
Clin Exp Rheumatol 2001 Mar-Apr;19(2):211-7. PMID: 11326488
Keul R, Heinrich PC, Müller-newen G, Muller K, Woo P
Cytokine 1998 Sep;10(9):729-34. doi: 10.1006/cyto.1997.0343. PMID: 9770335
Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries S, Woo P
J Clin Invest 1998 Oct 1;102(7):1369-76. doi: 10.1172/JCI2629. PMID: 9769329Free PMC Article
van der Net J, Kuis W, Prakken AB, Lukkassen I, Sinnema G, Hutter AP, Brackel HJ, de Wilde EJ, Helders PJ
Scand J Rheumatol 1997;26(3):188-96. doi: 10.3109/03009749709065680. PMID: 9225874
Ravelli A, Ramenghi B, Di Fuccia G, Ruperto N, Zonta L, Martini A
Acta Paediatr 1994 Apr;83(4):428-32. doi: 10.1111/j.1651-2227.1994.tb18135.x. PMID: 8025404

Diagnosis

Oguntona AS, Adelowo O
Niger J Med 2008 Jan-Mar;17(1):112-4. doi: 10.4314/njm.v17i1.37369. PMID: 18390147
Kounami S, Yoshiyama M, Nakayama K, Okuda M, Okuda S, Aoyagi N, Yoshikawa N
Acta Haematol 2005;113(2):124-9. doi: 10.1159/000083450. PMID: 15802891
Modesto C, Woo P, García-Consuegra J, Merino R, García-Granero M, Arnal C, Prieur AM
Clin Exp Rheumatol 2001 Mar-Apr;19(2):211-7. PMID: 11326488
Lin SJ, Jaing TH
Clin Rheumatol 1999;18(3):241-3. doi: 10.1007/s100670050092. PMID: 11206351
Wedderburn LR, Kwan JT, Thompson PW, Rudge SR
Br J Rheumatol 1992 Feb;31(2):121-3. doi: 10.1093/rheumatology/31.2.121. PMID: 1737227

Therapy

Kounami S, Yoshiyama M, Nakayama K, Okuda M, Okuda S, Aoyagi N, Yoshikawa N
Acta Haematol 2005;113(2):124-9. doi: 10.1159/000083450. PMID: 15802891
Lin SJ, Jaing TH
Clin Rheumatol 1999;18(3):241-3. doi: 10.1007/s100670050092. PMID: 11206351
Horneff G, Dirksen U, Schulze-Koops H, Emmrich F, Wahn V
Ann Rheum Dis 1995 Oct;54(10):846-9. doi: 10.1136/ard.54.10.846. PMID: 7492226Free PMC Article
Ravelli A, Ramenghi B, Di Fuccia G, Ruperto N, Zonta L, Martini A
Acta Paediatr 1994 Apr;83(4):428-32. doi: 10.1111/j.1651-2227.1994.tb18135.x. PMID: 8025404
Martini A, Ravelli A, Di Fuccia G, Rosti V, Cazzola M, Barosi G
Lancet 1994 Oct 15;344(8929):1052-4. doi: 10.1016/s0140-6736(94)91710-8. PMID: 7864944

Prognosis

Modesto C, Woo P, García-Consuegra J, Merino R, García-Granero M, Arnal C, Prieur AM
Clin Exp Rheumatol 2001 Mar-Apr;19(2):211-7. PMID: 11326488
Lin SJ, Jaing TH
Clin Rheumatol 1999;18(3):241-3. doi: 10.1007/s100670050092. PMID: 11206351
Cazzola M, Ponchio L, de Benedetti F, Ravelli A, Rosti V, Beguin Y, Invernizzi R, Barosi G, Martini A
Blood 1996 Jun 1;87(11):4824-30. PMID: 8639855
Horneff G, Dirksen U, Schulze-Koops H, Emmrich F, Wahn V
Ann Rheum Dis 1995 Oct;54(10):846-9. doi: 10.1136/ard.54.10.846. PMID: 7492226Free PMC Article
Ravelli A, Ramenghi B, Di Fuccia G, Ruperto N, Zonta L, Martini A
Acta Paediatr 1994 Apr;83(4):428-32. doi: 10.1111/j.1651-2227.1994.tb18135.x. PMID: 8025404

Clinical prediction guides

Ishihara K, Hirano T
Cytokine Growth Factor Rev 2002 Aug-Oct;13(4-5):357-68. doi: 10.1016/s1359-6101(02)00027-8. PMID: 12220549
Modesto C, Woo P, García-Consuegra J, Merino R, García-Granero M, Arnal C, Prieur AM
Clin Exp Rheumatol 2001 Mar-Apr;19(2):211-7. PMID: 11326488
Cazzola M, Ponchio L, de Benedetti F, Ravelli A, Rosti V, Beguin Y, Invernizzi R, Barosi G, Martini A
Blood 1996 Jun 1;87(11):4824-30. PMID: 8639855
Horneff G, Dirksen U, Schulze-Koops H, Emmrich F, Wahn V
Ann Rheum Dis 1995 Oct;54(10):846-9. doi: 10.1136/ard.54.10.846. PMID: 7492226Free PMC Article
Ravelli A, Ramenghi B, Di Fuccia G, Ruperto N, Zonta L, Martini A
Acta Paediatr 1994 Apr;83(4):428-32. doi: 10.1111/j.1651-2227.1994.tb18135.x. PMID: 8025404

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...