U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Haemophilus meningitis

MedGen UID:
7535
•Concept ID:
C0025292
•
Disease or Syndrome
Synonyms: Haemophilus Meningitides; Haemophilus Meningitis; Hemophilus Meningitides; Hemophilus Meningitis; Meningitides, Haemophilus; Meningitides, Hemophilus; Meningitis, Haemophilus; Meningitis, Hemophilus
SNOMED CT: Haemophilus meningitis (192643004)
 
Monarch Initiative: MONDO:0000889

Definition

Infections of the nervous system caused by bacteria of the genus haemophilus, and marked by prominent inflammation of the meninges. haemophilus influenzae type B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHaemophilus meningitis

Professional guidelines

PubMed

Management of bacterial menigitis in 2016.
Javouhey E
Bull Acad Natl Med 2016 Jan;200(1):99-111. PMID: 29889417
Adjunctive dexamethasone treatment in acute bacterial meningitis.
Chaudhuri A
Lancet Neurol 2004 Jan;3(1):54-62. doi: 10.1016/s1474-4422(03)00623-9. PMID: 14693112
H. INFLUENZAE MENINGITIS: A CONTROLLED STUDY OF TREATMENT WITH AMPICILLIN.
THRUPP LD, LEEDOM JM, IVLER D, WEHRLE PF, BROWN JF, MATHIES AW, PORTNOY B
Postgrad Med J 1964 Dec;40(Suppl):SUPPL:119-26. doi: 10.1136/pgmj.40.suppl.119. PMID: 14246826Free PMC Article

Recent clinical studies

Etiology

Risk factors for community-acquired bacterial meningitis.
Lundbo LF, Benfield T
Infect Dis (Lond) 2017 Jun;49(6):433-444. doi: 10.1080/23744235.2017.1285046. PMID: 28301990
New diagnostic and therapeutic options in bacterial meningitis in infants and children.
Kim KS
Minerva Pediatr 2009 Oct;61(5):531-48. PMID: 19794379
Management of bacterial meningitis.
Hart CA, Cuevas LE, Marzouk O, Thomson AP, Sills J
J Antimicrob Chemother 1993 Jul;32 Suppl A:49-59. doi: 10.1093/jac/32.suppl_a.49. PMID: 8407698
Treatment of bacterial meningitis.
Schaad UB
Eur J Clin Microbiol 1986 Oct;5(5):492-7. doi: 10.1007/BF02017689. PMID: 3536497
Bacterial meningitis--1982.
Gold R
Am J Med 1983 Jul 28;75(1B):98-101. doi: 10.1016/0002-9343(83)90079-7. PMID: 6349348

Diagnosis

Bacterial meningitis post-PCV7: declining incidence and treatment.
Kowalsky RH, Jaffe DM
Pediatr Emerg Care 2013 Jun;29(6):758-66; quiz 767-8. doi: 10.1097/PEC.0b013e318294f709. PMID: 23736074
New diagnostic and therapeutic options in bacterial meningitis in infants and children.
Kim KS
Minerva Pediatr 2009 Oct;61(5):531-48. PMID: 19794379
Bacterial meningitis--an update.
Marks MI
Clin Pediatr (Phila) 1991 Dec;30(12):673-5. doi: 10.1177/000992289103001204. PMID: 1764875
Treatment of bacterial meningitis.
Schaad UB
Eur J Clin Microbiol 1986 Oct;5(5):492-7. doi: 10.1007/BF02017689. PMID: 3536497
Bacterial meningitis--1982.
Gold R
Am J Med 1983 Jul 28;75(1B):98-101. doi: 10.1016/0002-9343(83)90079-7. PMID: 6349348

Therapy

MenHibrix: a new combination meningococcal vaccine for infants and toddlers.
Hale SF, Camaione L, Lomaestro BM
Ann Pharmacother 2014 Mar;48(3):404-11. Epub 2013 Dec 18 doi: 10.1177/1060028013514375. PMID: 24353263
Bacterial meningitis post-PCV7: declining incidence and treatment.
Kowalsky RH, Jaffe DM
Pediatr Emerg Care 2013 Jun;29(6):758-66; quiz 767-8. doi: 10.1097/PEC.0b013e318294f709. PMID: 23736074
Adjunctive dexamethasone treatment in acute bacterial meningitis.
Chaudhuri A
Lancet Neurol 2004 Jan;3(1):54-62. doi: 10.1016/s1474-4422(03)00623-9. PMID: 14693112
Cephalosporin antibiotic agents.
Kemp R
Med J Aust 1984 Sep 29;141(7):437-42. doi: 10.5694/j.1326-5377.1984.tb132856.x. PMID: 6472182
Pharmacokinetic and bacteriological correlations between antimicrobial therapy of experimental meningitis in rabbits and meningitis in humans: a review.
McCracken GH Jr
J Antimicrob Chemother 1983 Dec;12 Suppl D:97-108. doi: 10.1093/jac/12.suppl_d.97. PMID: 6365874

Prognosis

The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review.
Davis S, Feikin D, Johnson HL
BMC Public Health 2013;13 Suppl 3(Suppl 3):S21. Epub 2013 Sep 17 doi: 10.1186/1471-2458-13-S3-S21. PMID: 24564188Free PMC Article
Bacterial meningitis post-PCV7: declining incidence and treatment.
Kowalsky RH, Jaffe DM
Pediatr Emerg Care 2013 Jun;29(6):758-66; quiz 767-8. doi: 10.1097/PEC.0b013e318294f709. PMID: 23736074
Chemoprophylaxis of bacterial meningitis.
Cuevas LE, Hart CA
J Antimicrob Chemother 1993 Feb;31 Suppl B:79-91. doi: 10.1093/jac/31.suppl_b.79. PMID: 8449848
Management of bacterial meningitis.
Hart CA, Cuevas LE, Marzouk O, Thomson AP, Sills J
J Antimicrob Chemother 1993 Jul;32 Suppl A:49-59. doi: 10.1093/jac/32.suppl_a.49. PMID: 8407698
Treatment of bacterial meningitis.
Schaad UB
Eur J Clin Microbiol 1986 Oct;5(5):492-7. doi: 10.1007/BF02017689. PMID: 3536497

Clinical prediction guides

Estimating the global and regional burden of meningitis in children caused by Haemophilus influenzae type b: A systematic review and meta-analysis.
Park JJ, Narayanan S, Tiefenbach J, Lukšić I, Ale BM, Adeloye D, Rudan I
J Glob Health 2022;12:04014. Epub 2022 Mar 5 doi: 10.7189/jogh.12.04014. PMID: 35265327Free PMC Article
Community-acquired Haemophilus influenzae meningitis in adults.
Chekrouni N, Koelman DLH, Brouwer MC, van der Ende A, van de Beek D
J Infect 2021 May;82(5):145-150. Epub 2021 Mar 25 doi: 10.1016/j.jinf.2021.03.016. PMID: 33774020
Haemophilus influenzae type b disease in the era of conjugate vaccines: critical factors for successful eradication.
Slack M, Esposito S, Haas H, Mihalyi A, Nissen M, Mukherjee P, Harrington L
Expert Rev Vaccines 2020 Oct;19(10):903-917. Epub 2020 Oct 10 doi: 10.1080/14760584.2020.1825948. PMID: 32962476
Haemophilus influenzae type b vaccination and anthropometric, cognitive, and schooling outcomes among Indian children.
Nandi A, Deolalikar AB, Bloom DE, Laxminarayan R
Ann N Y Acad Sci 2019 Aug;1449(1):70-82. Epub 2019 Jun 10 doi: 10.1111/nyas.14127. PMID: 31180594Free PMC Article
The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review.
Davis S, Feikin D, Johnson HL
BMC Public Health 2013;13 Suppl 3(Suppl 3):S21. Epub 2013 Sep 17 doi: 10.1186/1471-2458-13-S3-S21. PMID: 24564188Free PMC Article

Recent systematic reviews

Estimating the global and regional burden of meningitis in children caused by Haemophilus influenzae type b: A systematic review and meta-analysis.
Park JJ, Narayanan S, Tiefenbach J, Lukšić I, Ale BM, Adeloye D, Rudan I
J Glob Health 2022;12:04014. Epub 2022 Mar 5 doi: 10.7189/jogh.12.04014. PMID: 35265327Free PMC Article
Incidence and aetiology of bacterial meningitis among children aged 1-59 months in South Asia: systematic review and meta-analysis.
Ali M, Chang BA, Johnson KW, Morris SK
Vaccine 2018 Sep 18;36(39):5846-5857. Epub 2018 Aug 23 doi: 10.1016/j.vaccine.2018.07.037. PMID: 30145101
The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review.
Davis S, Feikin D, Johnson HL
BMC Public Health 2013;13 Suppl 3(Suppl 3):S21. Epub 2013 Sep 17 doi: 10.1186/1471-2458-13-S3-S21. PMID: 24564188Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...