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T-cell adult acute lymphocytic leukemia

MedGen UID:
79009
Concept ID:
C0279592
Neoplastic Process
Synonyms: acute Adult T-cell Leukemia-lymphoma; adult acute lymphoblastic leukaemia of T cell; adult acute lymphoblastic leukemia of T cell; adult precursor T lymphoblastic leukaemia; adult precursor T lymphoblastic leukemia; adult precursor T-lymphoblastic leukaemia; Adult Precursor T-Lymphoblastic Leukemia; adult precursor T-lymphoblastic leukemia; adult T acute lymphoblastic leukaemia; Adult T Acute Lymphoblastic Leukemia; adult T acute lymphoblastic leukemia; Adult T-Acute Lymphoblastic Leukemia; adult T-cell acute lymphoblastic leukaemia; Adult T-Cell Acute Lymphoblastic Leukemia; adult T-cell acute lymphoblastic leukemia; T Acute Lymphoblastic Leukaemia; T Acute Lymphoblastic Leukemia; T cell adult acute lymphoblastic leukaemia; T cell adult acute lymphoblastic leukemia; T cell adult acute lymphocytic leukaemia; T cell adult acute lymphocytic leukemia; T Cell Adult ALL; T cell adult ALL; T-Cell Adult ALL; T-cell adult ALL
 
Monarch Initiative: MONDO:0003539

Definition

An acute T-lymphoblastic leukemia occurring in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVT-cell adult acute lymphocytic leukemia

Professional guidelines

PubMed

Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Samra B, Jabbour E, Ravandi F, Kantarjian H, Short NJ
J Hematol Oncol 2020 Jun 5;13(1):70. doi: 10.1186/s13045-020-00905-2. PMID: 32503572Free PMC Article
Gregory S
Semin Oncol Nurs 2019 Dec;35(6):150951. Epub 2019 Nov 20 doi: 10.1016/j.soncn.2019.150951. PMID: 31759820

Recent clinical studies

Etiology

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Jabbour E, Short NJ, Jain N, Haddad FG, Welch MA, Ravandi F, Kantarjian H
J Hematol Oncol 2023 Mar 16;16(1):22. doi: 10.1186/s13045-023-01409-5. PMID: 36927623Free PMC Article
Teachey DT, Devidas M, Wood BL, Chen Z, Hayashi RJ, Hermiston ML, Annett RD, Archer JH, Asselin BL, August KJ, Cho SY, Dunsmore KP, Fisher BT, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju AI, Lam A, Messinger YH, Miles RR, Okada M, Patel SI, Schafer ES, Schechter T, Singh N, Steele AC, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay P, Bollard CM, Loh ML, Hunger SP, Raetz EA
J Clin Oncol 2022 Jul 1;40(19):2106-2118. Epub 2022 Mar 10 doi: 10.1200/JCO.21.02678. PMID: 35271306Free PMC Article
Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Brown PA, Ji L, Xu X, Devidas M, Hogan LE, Borowitz MJ, Raetz EA, Zugmaier G, Sharon E, Bernhardt MB, Terezakis SA, Gore L, Whitlock JA, Pulsipher MA, Hunger SP, Loh ML
JAMA 2021 Mar 2;325(9):833-842. doi: 10.1001/jama.2021.0669. PMID: 33651090Free PMC Article

Diagnosis

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772
Aldoss I, Forman SJ, Pullarkat V
J Oncol Pract 2019 Feb;15(2):67-75. doi: 10.1200/JOP.18.00271. PMID: 30763199
Iacobucci I, Mullighan CG
J Clin Oncol 2017 Mar 20;35(9):975-983. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.70.7836. PMID: 28297628Free PMC Article
Onciu M
Hematol Oncol Clin North Am 2009 Aug;23(4):655-74. doi: 10.1016/j.hoc.2009.04.009. PMID: 19577163

Therapy

Amini L, Silbert SK, Maude SL, Nastoupil LJ, Ramos CA, Brentjens RJ, Sauter CS, Shah NN, Abou-El-Enein M
Nat Rev Clin Oncol 2022 May;19(5):342-355. Epub 2022 Mar 22 doi: 10.1038/s41571-022-00607-3. PMID: 35318469
Brown PA, Ji L, Xu X, Devidas M, Hogan LE, Borowitz MJ, Raetz EA, Zugmaier G, Sharon E, Bernhardt MB, Terezakis SA, Gore L, Whitlock JA, Pulsipher MA, Hunger SP, Loh ML
JAMA 2021 Mar 2;325(9):833-842. doi: 10.1001/jama.2021.0669. PMID: 33651090Free PMC Article
Hu Y, Zhou Y, Zhang M, Ge W, Li Y, Yang L, Wei G, Han L, Wang H, Yu S, Chen Y, Wang Y, He X, Zhang X, Gao M, Yang J, Li X, Ren J, Huang H
Clin Cancer Res 2021 May 15;27(10):2764-2772. Epub 2021 Feb 24 doi: 10.1158/1078-0432.CCR-20-3863. PMID: 33627493
Samra B, Jabbour E, Ravandi F, Kantarjian H, Short NJ
J Hematol Oncol 2020 Jun 5;13(1):70. doi: 10.1186/s13045-020-00905-2. PMID: 32503572Free PMC Article
Gregory S
Semin Oncol Nurs 2019 Dec;35(6):150951. Epub 2019 Nov 20 doi: 10.1016/j.soncn.2019.150951. PMID: 31759820

Prognosis

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Amini L, Silbert SK, Maude SL, Nastoupil LJ, Ramos CA, Brentjens RJ, Sauter CS, Shah NN, Abou-El-Enein M
Nat Rev Clin Oncol 2022 May;19(5):342-355. Epub 2022 Mar 22 doi: 10.1038/s41571-022-00607-3. PMID: 35318469
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772
Aldoss I, Forman SJ, Pullarkat V
J Oncol Pract 2019 Feb;15(2):67-75. doi: 10.1200/JOP.18.00271. PMID: 30763199
Onciu M
Hematol Oncol Clin North Am 2009 Aug;23(4):655-74. doi: 10.1016/j.hoc.2009.04.009. PMID: 19577163

Clinical prediction guides

Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Hu Y, Zhou Y, Zhang M, Ge W, Li Y, Yang L, Wei G, Han L, Wang H, Yu S, Chen Y, Wang Y, He X, Zhang X, Gao M, Yang J, Li X, Ren J, Huang H
Clin Cancer Res 2021 May 15;27(10):2764-2772. Epub 2021 Feb 24 doi: 10.1158/1078-0432.CCR-20-3863. PMID: 33627493
Aldoss I, Forman SJ, Pullarkat V
J Oncol Pract 2019 Feb;15(2):67-75. doi: 10.1200/JOP.18.00271. PMID: 30763199
Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH, Levine BL, Wood P, Taran T, Leung M, Mueller KT, Zhang Y, Sen K, Lebwohl D, Pulsipher MA, Grupp SA
N Engl J Med 2018 Feb 1;378(5):439-448. doi: 10.1056/NEJMoa1709866. PMID: 29385370Free PMC Article
Kantarjian HM, O'Brien S, Smith TL, Cortes J, Giles FJ, Beran M, Pierce S, Huh Y, Andreeff M, Koller C, Ha CS, Keating MJ, Murphy S, Freireich EJ
J Clin Oncol 2000 Feb;18(3):547-61. doi: 10.1200/JCO.2000.18.3.547. PMID: 10653870

Recent systematic reviews

Andrade AM, Teixeira VR, Pogue R, Figueiredo ACMG, Carvalho JL
Cytotherapy 2023 Sep;25(9):930-938. Epub 2023 Jun 20 doi: 10.1016/j.jcyt.2023.05.011. PMID: 37341664
Elsallab M, Ellithi M, Hempel S, Abdel-Azim H, Abou-El-Enein M
Cancer Gene Ther 2023 Jun;30(6):845-854. Epub 2023 Feb 7 doi: 10.1038/s41417-023-00593-3. PMID: 36750666Free PMC Article
Grant SJ, Grimshaw AA, Silberstein J, Murdaugh D, Wildes TM, Rosko AE, Giri S
Transplant Cell Ther 2022 Jun;28(6):294-302. Epub 2022 Mar 11 doi: 10.1016/j.jtct.2022.03.006. PMID: 35288347Free PMC Article
Grover P, Veilleux O, Tian L, Sun R, Previtera M, Curran E, Muffly L
Blood Adv 2022 Mar 8;6(5):1608-1618. doi: 10.1182/bloodadvances.2020003482. PMID: 34610109Free PMC Article
Aamir S, Anwar MY, Khalid F, Khan SI, Ali MA, Khattak ZE
Clin Lymphoma Myeloma Leuk 2021 Apr;21(4):e334-e347. Epub 2020 Dec 17 doi: 10.1016/j.clml.2020.12.010. PMID: 33573914

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