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Affective psychosis

MedGen UID:
7916
•Concept ID:
C0001723
•
Mental or Behavioral Dysfunction
Synonyms: Affective Disorder, Psychotic; Affective Disorders, Psychotic; Affective Psychoses; Disorder, Psychotic Affective; Disorders, Psychotic Affective; Psychoses, Affective; Psychotic Affective Disorder; Psychotic Affective Disorders
SNOMED CT: Affective psychosis (441704009)

Definition

The manifestation of psychotic symptoms, such as hallucinations or delusions, in the presence of a mood disorder. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAffective psychosis

Professional guidelines

PubMed

The effects of childhood adversity on treatment delays and its components in first-episode psychosis.
Veru F, MacDonald K, Malla A, Pruessner M, King S, Joober R, Shah J, Iyer SN
Psychiatry Res 2022 Feb;308:114341. Epub 2021 Dec 16 doi: 10.1016/j.psychres.2021.114341. PMID: 34953203
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
.
McCleery A, Nuechterlein KH
Dialogues Clin Neurosci 2019 Sep;21(3):239-248. doi: 10.31887/DCNS.2019.21.3/amccleery. PMID: 31749648Free PMC Article
The treatment gap in mental health care.
Kohn R, Saxena S, Levav I, Saraceno B
Bull World Health Organ 2004 Nov;82(11):858-66. Epub 2004 Dec 14 PMID: 15640922Free PMC Article

Recent clinical studies

Etiology

Postictal psychosis, a cause of secondary affective psychosis: A clinical description study of 77 patients.
Tarrada A, Hingray C, Aron O, Dupont S, Maillard L, de Toffol B
Epilepsy Behav 2022 Feb;127:108553. Epub 2022 Jan 21 doi: 10.1016/j.yebeh.2022.108553. PMID: 35074723
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
.
McCleery A, Nuechterlein KH
Dialogues Clin Neurosci 2019 Sep;21(3):239-248. doi: 10.31887/DCNS.2019.21.3/amccleery. PMID: 31749648Free PMC Article
Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective.
Sheffield JM, Karcher NR, Barch DM
Neuropsychol Rev 2018 Dec;28(4):509-533. Epub 2018 Oct 20 doi: 10.1007/s11065-018-9388-2. PMID: 30343458Free PMC Article
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249
Insomnia and paranoia.
Freeman D, Pugh K, Vorontsova N, Southgate L
Schizophr Res 2009 Mar;108(1-3):280-4. Epub 2008 Dec 20 doi: 10.1016/j.schres.2008.12.001. PMID: 19097752Free PMC Article

Diagnosis

Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: I. Clinical Outcomes.
Jester DJ, Thomas ML, Sturm ET, Harvey PD, Keshavan M, Davis BJ, Saxena S, Tampi R, Leutwyler H, Compton MT, Palmer BW, Jeste DV
Schizophr Bull 2023 Jul 4;49(4):837-850. doi: 10.1093/schbul/sbad023. PMID: 37022779Free PMC Article
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
.
McCleery A, Nuechterlein KH
Dialogues Clin Neurosci 2019 Sep;21(3):239-248. doi: 10.31887/DCNS.2019.21.3/amccleery. PMID: 31749648Free PMC Article
Postpartum Psychosis: Madness, Mania, and Melancholia in Motherhood.
Bergink V, Rasgon N, Wisner KL
Am J Psychiatry 2016 Dec 1;173(12):1179-1188. Epub 2016 Sep 9 doi: 10.1176/appi.ajp.2016.16040454. PMID: 27609245
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249
The treatment gap in mental health care.
Kohn R, Saxena S, Levav I, Saraceno B
Bull World Health Organ 2004 Nov;82(11):858-66. Epub 2004 Dec 14 PMID: 15640922Free PMC Article

Therapy

Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
.
McCleery A, Nuechterlein KH
Dialogues Clin Neurosci 2019 Sep;21(3):239-248. doi: 10.31887/DCNS.2019.21.3/amccleery. PMID: 31749648Free PMC Article
Lipid profile disturbances in antipsychotic-naive patients with first-episode non-affective psychosis: A systematic review and meta-analysis.
Misiak B, Stańczykiewicz B, Łaczmański Ł, Frydecka D
Schizophr Res 2017 Dec;190:18-27. Epub 2017 Mar 20 doi: 10.1016/j.schres.2017.03.031. PMID: 28325572
Postpartum Psychosis: Madness, Mania, and Melancholia in Motherhood.
Bergink V, Rasgon N, Wisner KL
Am J Psychiatry 2016 Dec 1;173(12):1179-1188. Epub 2016 Sep 9 doi: 10.1176/appi.ajp.2016.16040454. PMID: 27609245
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249
Treatment for therapy-resistant depression.
Kielholz P
Psychopathology 1986;19 Suppl 2:194-200. doi: 10.1159/000285154. PMID: 2883699

Prognosis

Ecological momentary facial emotion recognition in psychotic disorders.
Depp CA, Kamarsu S, Filip TF, Parrish EM, Harvey PD, Granholm EL, Chalker S, Moore RC, Pinkham A
Psychol Med 2022 Oct;52(13):2531-2539. Epub 2021 Jan 12 doi: 10.1017/S0033291720004419. PMID: 33431072Free PMC Article
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
.
McCleery A, Nuechterlein KH
Dialogues Clin Neurosci 2019 Sep;21(3):239-248. doi: 10.31887/DCNS.2019.21.3/amccleery. PMID: 31749648Free PMC Article
Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective.
Sheffield JM, Karcher NR, Barch DM
Neuropsychol Rev 2018 Dec;28(4):509-533. Epub 2018 Oct 20 doi: 10.1007/s11065-018-9388-2. PMID: 30343458Free PMC Article
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249
Insomnia and paranoia.
Freeman D, Pugh K, Vorontsova N, Southgate L
Schizophr Res 2009 Mar;108(1-3):280-4. Epub 2008 Dec 20 doi: 10.1016/j.schres.2008.12.001. PMID: 19097752Free PMC Article

Clinical prediction guides

Association between free thyroxine levels and clinical phenotype in first-episode psychosis: a prospective observational study.
Gine-Serven E, Martinez-Ramirez M, Boix-Quintana E, Davi-Loscos E, Guanyabens N, Casado V, Muriana D, Torres-Rivas C, Cuesta MJ, Labad J
PeerJ 2023;11:e15347. Epub 2023 Jun 2 doi: 10.7717/peerj.15347. PMID: 37283900Free PMC Article
Ecological momentary facial emotion recognition in psychotic disorders.
Depp CA, Kamarsu S, Filip TF, Parrish EM, Harvey PD, Granholm EL, Chalker S, Moore RC, Pinkham A
Psychol Med 2022 Oct;52(13):2531-2539. Epub 2021 Jan 12 doi: 10.1017/S0033291720004419. PMID: 33431072Free PMC Article
Mechanistic insights into the genetics of affective psychosis from Prader-Willi syndrome.
Aman LCS, Manning KE, Whittington JE, Holland AJ
Lancet Psychiatry 2018 Apr;5(4):370-378. Epub 2018 Jan 16 doi: 10.1016/S2215-0366(18)30009-9. PMID: 29352661
Insomnia and paranoia.
Freeman D, Pugh K, Vorontsova N, Southgate L
Schizophr Res 2009 Mar;108(1-3):280-4. Epub 2008 Dec 20 doi: 10.1016/j.schres.2008.12.001. PMID: 19097752Free PMC Article
Pharmacotherapy of first-episode psychosis.
Lambert M, Conus P, Lambert T, McGorry PD
Expert Opin Pharmacother 2003 May;4(5):717-50. doi: 10.1517/14656566.4.5.717. PMID: 12739997

Recent systematic reviews

The relationship between the therapeutic alliance in psychotherapy and suicidal experiences: A systematic review.
Huggett C, Gooding P, Haddock G, Quigley J, Pratt D
Clin Psychol Psychother 2022 Jul;29(4):1203-1235. Epub 2022 Feb 25 doi: 10.1002/cpp.2726. PMID: 35168297Free PMC Article
Burden of severe maternal peripartum mental disorders in low- and middle-income countries: a systematic review.
Kalra H, Tran T, Romero L, Chandra P, Fisher J
Arch Womens Ment Health 2022 Apr;25(2):267-275. Epub 2022 Jan 21 doi: 10.1007/s00737-021-01201-9. PMID: 35061103Free PMC Article
Are there reliable and valid measures of anxiety for people with psychosis? A systematic review of psychometric properties.
Smith EL, Garety PA, Harding H, Hardy A
Psychol Psychother 2021 Mar;94(1):173-198. Epub 2019 Dec 27 doi: 10.1111/papt.12265. PMID: 31880406
The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis.
Fett AK, Viechtbauer W, Dominguez MD, Penn DL, van Os J, Krabbendam L
Neurosci Biobehav Rev 2011 Jan;35(3):573-88. Epub 2010 Jul 8 doi: 10.1016/j.neubiorev.2010.07.001. PMID: 20620163
Antipsychotic drugs for non-affective psychosis during pregnancy and postpartum.
Webb RT, Howard L, Abel KM
Cochrane Database Syst Rev 2004;(2):CD004411. doi: 10.1002/14651858.CD004411.pub2. PMID: 15106251

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