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Respirovirus infectious disease

MedGen UID:
811417
•Concept ID:
C3714630
•
Disease or Syndrome
Synonyms: Infections, Respirovirus; Respirovirus Infections
SNOMED CT: Disease caused by Respirovirus (407495009)
 
Monarch Initiative: MONDO:0005940

Definition

Infections with viruses of the genus respirovirus, family paramyxoviridae. Host cell infection occurs by adsorption, via hemagglutinin, to the cell surface. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRespirovirus infectious disease

Professional guidelines

PubMed

Epidemiology and clinical outcome of lower respiratory tract infections by respiratory syncytial virus or parainfluenza virus type 3 in adults receiving treatment for either acute leukemia or severe aplastic anemia: a retrospective single center study.
Bigliardi S, Morselli M, Potenza L, Riva G, Coluccio V, Maccaferri M, Paolini A, Colaci E, Fantuzzi V, Soci F, Nasillo V, Messerotti A, Arletti L, Pioli V, Lugli E, Gilioli A, Quadrelli C, Vallerini D, Barozzi P, Lagreca I, Marasca R, Narni F, Franceschini E, Codeluppi M, Mussini C, Luppi M, Forghieri F
Ann Hematol 2015 Nov;94(11):1931-4. Epub 2015 Jul 25 doi: 10.1007/s00277-015-2455-3. PMID: 26204825
Incidence, molecular epidemiology and clinical presentations of human metapneumovirus; assessment of its importance as a diagnostic screening target.
Gaunt E, McWilliam-Leitch EC, Templeton K, Simmonds P
J Clin Virol 2009 Dec;46(4):318-24. Epub 2009 Oct 12 doi: 10.1016/j.jcv.2009.09.016. PMID: 19819755
Ribavirin aerosol treatment of serious respiratory syncytial virus infection in infants.
Rodriguez WJ, Parrott RH
Infect Dis Clin North Am 1987 Jun;1(2):425-39. PMID: 3332796

Recent clinical studies

Etiology

Modeling Infection and Tropism of Human Parainfluenza Virus Type 3 in Ferrets.
Rijsbergen LC, Schmitz KS, Begeman L, Drew-Bear J, Gommers L, Lamers MM, Greninger AL, Haagmans BL, Porotto M, de Swart RL, Moscona A, de Vries RD
mBio 2021 Feb 22;13(1):e0383121. Epub 2022 Feb 15 doi: 10.1128/mbio.03831-21. PMID: 35164568Free PMC Article
Progress in the development of human parainfluenza virus vaccines.
Schmidt AC, Schaap-Nutt A, Bartlett EJ, Schomacker H, Boonyaratanakornkit J, Karron RA, Collins PL
Expert Rev Respir Med 2011 Aug;5(4):515-26. doi: 10.1586/ers.11.32. PMID: 21859271Free PMC Article
Respiratory syncytial virus.
Filippell MB, Rearick T
Nurs Clin North Am 1993 Sep;28(3):651-71. PMID: 8367331
Transmission of infectious diseases in children.
Goldmann DA
Pediatr Rev 1992 Aug;13(8):283-93. doi: 10.1542/pir.13-8-283. PMID: 1332011
Respiratory syncytial virus: its transmission in the hospital environment.
Hall CB
Yale J Biol Med 1982 May-Aug;55(3-4):219-23. PMID: 6758370Free PMC Article

Diagnosis

Broad Impacts of Coronavirus Disease 2019 (COVID-19) Pandemic on Acute Respiratory Infections in China: An Observational Study.
Li ZJ, Yu LJ, Zhang HY, Shan CX, Lu QB, Zhang XA, Ren X, Zhang CH, Wang YF, Lin SH, Xu Q, Jiang BG, Jiang T, Lv CL, Chen JJ, Gao GF, Yang WZ, Wang LP, Yang Y, Fang LQ, Liu W; Chinese Centers for Disease Control and Prevention (CDC) Etiology Surveillance Study Team of Acute Respiratory Infections
Clin Infect Dis 2022 Aug 24;75(1):e1054-e1062. doi: 10.1093/cid/ciab942. PMID: 34788811Free PMC Article
Healthcare-associated atypical pneumonia.
Forgie S, Marrie TJ
Semin Respir Crit Care Med 2009 Feb;30(1):67-85. Epub 2009 Feb 6 doi: 10.1055/s-0028-1119811. PMID: 19199189
Lung infections in children.
Stark JM
Curr Opin Pediatr 1993 Jun;5(3):273-80. doi: 10.1097/00008480-199306000-00005. PMID: 8374645
The need for new antiviral agents.
Freestone DS
Antiviral Res 1985 Dec;5(6):307-24. doi: 10.1016/0166-3542(85)90001-4. PMID: 3004326Free PMC Article
Rapid diagnosis of virus diseases.
Flewett TH
Br Med Bull 1985 Oct;41(4):315-21. doi: 10.1093/oxfordjournals.bmb.a072070. PMID: 2996682Free PMC Article

Therapy

Might Routine Vitamin A Monitoring in Cystic Fibrosis Patients Reduce Virus-Mediated Lung Pathology?
Sealy RE, Surman SL, Vogel P, Hurwitz JL
Front Immunol 2021;12:704391. Epub 2021 Nov 9 doi: 10.3389/fimmu.2021.704391. PMID: 34858393Free PMC Article
Prevalence of human respiratory syncytial virus, parainfluenza and adenoviruses in East Africa Community partner states of Kenya, Tanzania, and Uganda: A systematic review and meta-analysis (2007-2020).
Umuhoza T, Bulimo WD, Oyugi J, Musabyimana JP, Kinengyere AA, Mancuso JD
PLoS One 2021;16(4):e0249992. Epub 2021 Apr 27 doi: 10.1371/journal.pone.0249992. PMID: 33905425Free PMC Article
Progress in the development of human parainfluenza virus vaccines.
Schmidt AC, Schaap-Nutt A, Bartlett EJ, Schomacker H, Boonyaratanakornkit J, Karron RA, Collins PL
Expert Rev Respir Med 2011 Aug;5(4):515-26. doi: 10.1586/ers.11.32. PMID: 21859271Free PMC Article
Progress in filovirus vaccine development: evaluating the potential for clinical use.
Falzarano D, Geisbert TW, Feldmann H
Expert Rev Vaccines 2011 Jan;10(1):63-77. doi: 10.1586/erv.10.152. PMID: 21162622Free PMC Article
The need for new antiviral agents.
Freestone DS
Antiviral Res 1985 Dec;5(6):307-24. doi: 10.1016/0166-3542(85)90001-4. PMID: 3004326Free PMC Article

Prognosis

A rapid and label-free platform for virus capture and identification from clinical samples.
Yeh YT, Gulino K, Zhang Y, Sabestien A, Chou TW, Zhou B, Lin Z, Albert I, Lu H, Swaminathan V, Ghedin E, Terrones M
Proc Natl Acad Sci U S A 2020 Jan 14;117(2):895-901. Epub 2019 Dec 27 doi: 10.1073/pnas.1910113117. PMID: 31882450Free PMC Article
Detailed genetic analyses of the HN gene in human respirovirus 3 detected in children with acute respiratory illness in the Iwate Prefecture, Japan.
Takahashi M, Nagasawa K, Saito K, Maisawa SI, Fujita K, Murakami K, Kuroda M, Ryo A, Kimura H
Infect Genet Evol 2018 Apr;59:155-162. Epub 2018 Feb 14 doi: 10.1016/j.meegid.2018.01.021. PMID: 29408530
Cross-immunity between strains explains the dynamical pattern of paramyxoviruses.
Bhattacharyya S, Gesteland PH, Korgenski K, Bjørnstad ON, Adler FR
Proc Natl Acad Sci U S A 2015 Oct 27;112(43):13396-400. Epub 2015 Oct 12 doi: 10.1073/pnas.1516698112. PMID: 26460003Free PMC Article
Respiratory virus infection in infants and children.
Hammond S, Chenever E, Durbin JE
Pediatr Dev Pathol 2007 May-Jun;10(3):172-80. doi: 10.2350/07-02-0238.1. PMID: 17535096
Bronchiolitis following infection in adults and children.
Penn CC, Liu C
Clin Chest Med 1993 Dec;14(4):645-54. PMID: 8313669

Clinical prediction guides

A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology.
Lin Y, Khan M, Weynand B, Laporte M, Coenjaerts F, Babusis D, Bilello JP, Mombaerts P, Jochmans D, Neyts J
Nat Commun 2024 Sep 5;15(1):7765. doi: 10.1038/s41467-024-52071-5. PMID: 39237507Free PMC Article
Broad Impacts of Coronavirus Disease 2019 (COVID-19) Pandemic on Acute Respiratory Infections in China: An Observational Study.
Li ZJ, Yu LJ, Zhang HY, Shan CX, Lu QB, Zhang XA, Ren X, Zhang CH, Wang YF, Lin SH, Xu Q, Jiang BG, Jiang T, Lv CL, Chen JJ, Gao GF, Yang WZ, Wang LP, Yang Y, Fang LQ, Liu W; Chinese Centers for Disease Control and Prevention (CDC) Etiology Surveillance Study Team of Acute Respiratory Infections
Clin Infect Dis 2022 Aug 24;75(1):e1054-e1062. doi: 10.1093/cid/ciab942. PMID: 34788811Free PMC Article
A rapid and label-free platform for virus capture and identification from clinical samples.
Yeh YT, Gulino K, Zhang Y, Sabestien A, Chou TW, Zhou B, Lin Z, Albert I, Lu H, Swaminathan V, Ghedin E, Terrones M
Proc Natl Acad Sci U S A 2020 Jan 14;117(2):895-901. Epub 2019 Dec 27 doi: 10.1073/pnas.1910113117. PMID: 31882450Free PMC Article
Detailed genetic analyses of the HN gene in human respirovirus 3 detected in children with acute respiratory illness in the Iwate Prefecture, Japan.
Takahashi M, Nagasawa K, Saito K, Maisawa SI, Fujita K, Murakami K, Kuroda M, Ryo A, Kimura H
Infect Genet Evol 2018 Apr;59:155-162. Epub 2018 Feb 14 doi: 10.1016/j.meegid.2018.01.021. PMID: 29408530
Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections.
Frassanito A, Nenna R, Nicolai A, Pierangeli A, Tozzi AE, Stefanelli P, Carsetti R, Concato C, Schiavoni I, Midulla F; Pertussis study group
BMC Infect Dis 2017 Jul 12;17(1):492. doi: 10.1186/s12879-017-2567-6. PMID: 28701160Free PMC Article

Recent systematic reviews

Prevalence of human respiratory syncytial virus, parainfluenza and adenoviruses in East Africa Community partner states of Kenya, Tanzania, and Uganda: A systematic review and meta-analysis (2007-2020).
Umuhoza T, Bulimo WD, Oyugi J, Musabyimana JP, Kinengyere AA, Mancuso JD
PLoS One 2021;16(4):e0249992. Epub 2021 Apr 27 doi: 10.1371/journal.pone.0249992. PMID: 33905425Free PMC Article

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