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RNA Virus Infections

MedGen UID:
11250
•Concept ID:
C0035690
•
Disease or Syndrome
Synonyms: Infection, RNA Virus; Infections, RNA Virus; RNA Virus Infection; Virus Infection, RNA; Virus Infections, RNA

Definition

Diseases caused by RNA VIRUSES. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRNA Virus Infections

Professional guidelines

PubMed

Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19.
Demarest JF, Kienle M, Boytz R, Ayres M, Kim EJ, Patten JJ, Chung D, Gandhi V, Davey RA, Sykes DB, Shohdy N, Pottage JC Jr, Kumar VS
Antiviral Res 2022 Oct;206:105403. Epub 2022 Aug 28 doi: 10.1016/j.antiviral.2022.105403. PMID: 36041646Free PMC Article
Melatonin may decrease risk for and aid treatment of COVID-19 and other RNA viral infections.
DiNicolantonio JJ, McCarty M, Barroso-Aranda J
Open Heart 2021 Mar;8(1) doi: 10.1136/openhrt-2020-001568. PMID: 33741691Free PMC Article
Nucleosides for the treatment of respiratory RNA virus infections.
Jordan PC, Stevens SK, Deval J
Antivir Chem Chemother 2018 Jan-Dec;26:2040206618764483. doi: 10.1177/2040206618764483. PMID: 29562753Free PMC Article

Recent clinical studies

Etiology

Role of Host-Mediated Post-Translational Modifications (PTMs) in RNA Virus Pathogenesis.
Kumar R, Mehta D, Mishra N, Nayak D, Sunil S
Int J Mol Sci 2020 Dec 30;22(1) doi: 10.3390/ijms22010323. PMID: 33396899Free PMC Article
Viral infection and atherosclerosis.
Hemmat N, Ebadi A, Badalzadeh R, Memar MY, Baghi HB
Eur J Clin Microbiol Infect Dis 2018 Dec;37(12):2225-2233. Epub 2018 Sep 5 doi: 10.1007/s10096-018-3370-z. PMID: 30187247
HEV and transfusion-recipient risk.
Izopet J, Lhomme S, Chapuy-Regaud S, Mansuy JM, Kamar N, Abravanel F
Transfus Clin Biol 2017 Sep;24(3):176-181. Epub 2017 Jul 6 doi: 10.1016/j.tracli.2017.06.012. PMID: 28690036
Respiratory RNA Viruses.
Hodinka RL
Microbiol Spectr 2016 Aug;4(4) doi: 10.1128/microbiolspec.DMIH2-0028-2016. PMID: 27726802
Viral-associated thrombotic microangiopathies.
Lopes da Silva R
Hematol Oncol Stem Cell Ther 2011;4(2):51-9. doi: 10.5144/1658-3876.2011.51. PMID: 21727765

Diagnosis

Exosome-mediated PROTAC delivery for treatment of RNA viral infections and zoonosis.
Mukerjee N, Maitra S, Ghosh A, Alexiou A, Thorat ND
Drug Discov Today 2024 Jul;29(7):104044. Epub 2024 May 23 doi: 10.1016/j.drudis.2024.104044. PMID: 38796097
Respiratory RNA Viruses.
Hodinka RL
Microbiol Spectr 2016 Aug;4(4) doi: 10.1128/microbiolspec.DMIH2-0028-2016. PMID: 27726802
Antigenic properties of avian hepatitis E virus capsid protein.
Zhao Q, Syed SF, Zhou EM
Vet Microbiol 2015 Oct 22;180(1-2):10-4. Epub 2015 Aug 28 doi: 10.1016/j.vetmic.2015.08.016. PMID: 26340899
Bacterial infections, DNA virus infections, and RNA virus infections manifest differently in neutrophil receptor expression.
Lilius EM, Nuutila J
ScientificWorldJournal 2012;2012:527347. Epub 2012 Mar 12 doi: 10.1100/2012/527347. PMID: 22536142Free PMC Article
Biological terrorism.
Moran GJ, Talan DA, Abrahamian FM
Infect Dis Clin North Am 2008 Mar;22(1):145-87, vii. doi: 10.1016/j.idc.2007.12.003. PMID: 18295687Free PMC Article

Therapy

Single-Domain Antibodies as Therapeutics for Respiratory RNA Virus Infections.
Huang K, Ying T, Wu Y
Viruses 2022 May 27;14(6) doi: 10.3390/v14061162. PMID: 35746634Free PMC Article
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Sourimant J, Lieber CM, Aggarwal M, Cox RM, Wolf JD, Yoon JJ, Toots M, Ye C, Sticher Z, Kolykhalov AA, Martinez-Sobrido L, Bluemling GR, Natchus MG, Painter GR, Plemper RK
Science 2022 Jan 14;375(6577):161-167. Epub 2021 Dec 2 doi: 10.1126/science.abj5508. PMID: 34855509Free PMC Article
RNA virus reverse genetics and vaccine design.
Stobart CC, Moore ML
Viruses 2014 Jun 25;6(7):2531-50. doi: 10.3390/v6072531. PMID: 24967693Free PMC Article
Emerging antiviral drugs.
De Clercq E
Expert Opin Emerg Drugs 2008 Sep;13(3):393-416. doi: 10.1517/14728214.13.3.393. PMID: 18764719
Biological terrorism.
Moran GJ, Talan DA, Abrahamian FM
Infect Dis Clin North Am 2008 Mar;22(1):145-87, vii. doi: 10.1016/j.idc.2007.12.003. PMID: 18295687Free PMC Article

Prognosis

A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses.
Lin X, Liu Y, Chemparathy A, Pande T, La Russa M, Qi LS
Cell Rep Med 2021 Apr 20;2(4):100245. Epub 2021 Mar 23 doi: 10.1016/j.xcrm.2021.100245. PMID: 33778788Free PMC Article
Going to Bat(s) for Studies of Disease Tolerance.
Mandl JN, Schneider C, Schneider DS, Baker ML
Front Immunol 2018;9:2112. Epub 2018 Sep 20 doi: 10.3389/fimmu.2018.02112. PMID: 30294323Free PMC Article
Zika and chikungunya: mosquito-borne viruses in a changing world.
Shragai T, Tesla B, Murdock C, Harrington LC
Ann N Y Acad Sci 2017 Jul;1399(1):61-77. Epub 2017 Feb 10 doi: 10.1111/nyas.13306. PMID: 28187236
Viral population dynamics and virulence thresholds.
Lancaster KZ, Pfeiffer JK
Curr Opin Microbiol 2012 Aug;15(4):525-30. Epub 2012 Jun 2 doi: 10.1016/j.mib.2012.05.007. PMID: 22658738Free PMC Article
Bacterial infections, DNA virus infections, and RNA virus infections manifest differently in neutrophil receptor expression.
Lilius EM, Nuutila J
ScientificWorldJournal 2012;2012:527347. Epub 2012 Mar 12 doi: 10.1100/2012/527347. PMID: 22536142Free PMC Article

Clinical prediction guides

Zooming in and out: Exploring RNA Viral Infections with Multiscale Microscopic Methods.
Lyu CA, Shen Y, Zhang P
Viruses 2024 Sep 23;16(9) doi: 10.3390/v16091504. PMID: 39339980Free PMC Article
Going to Bat(s) for Studies of Disease Tolerance.
Mandl JN, Schneider C, Schneider DS, Baker ML
Front Immunol 2018;9:2112. Epub 2018 Sep 20 doi: 10.3389/fimmu.2018.02112. PMID: 30294323Free PMC Article
Hypoxia inducible factor one alpha and human viral pathogens.
Morinet F, Parent M, Pillet S, Koken M, Lebbé C, Capron C
Curr Res Transl Med 2017 Jan-Mar;65(1):7-9. Epub 2017 Mar 8 doi: 10.1016/j.retram.2016.11.002. PMID: 28340697
Fidelity Variants and RNA Quasispecies.
Bordería AV, Rozen-Gagnon K, Vignuzzi M
Curr Top Microbiol Immunol 2016;392:303-22. doi: 10.1007/82_2015_483. PMID: 26499340Free PMC Article
Viral population dynamics and virulence thresholds.
Lancaster KZ, Pfeiffer JK
Curr Opin Microbiol 2012 Aug;15(4):525-30. Epub 2012 Jun 2 doi: 10.1016/j.mib.2012.05.007. PMID: 22658738Free PMC Article

Recent systematic reviews

Vascular cutaneous manifestations of COVID-19 and RNA viral pathogens: a systematic review.
Karch JL, Okorie CL, Maymone MBC, Laughter M, Vashi NA
Clin Exp Dermatol 2024 Mar 21;49(4):313-324. doi: 10.1093/ced/llad377. PMID: 37936304
Key Factors That Enable the Pandemic Potential of RNA Viruses and Inter-Species Transmission: A Systematic Review.
Alvarez-Munoz S, Upegui-Porras N, Gomez AP, Ramirez-Nieto G
Viruses 2021 Mar 24;13(4) doi: 10.3390/v13040537. PMID: 33804942Free PMC Article
Hajj-associated viral respiratory infections: A systematic review.
Gautret P, Benkouiten S, Al-Tawfiq JA, Memish ZA
Travel Med Infect Dis 2016 Mar-Apr;14(2):92-109. Epub 2015 Dec 31 doi: 10.1016/j.tmaid.2015.12.008. PMID: 26781223Free PMC Article
Treatment of viral conjunctivitis with antiviral drugs.
Skevaki CL, Galani IE, Pararas MV, Giannopoulou KP, Tsakris A
Drugs 2011 Feb 12;71(3):331-47. doi: 10.2165/11585330-000000000-00000. PMID: 21319870

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