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Discoid Rash

MedGen UID:
812051
Concept ID:
C3805721
Finding
Synonym: Discoid rash

Definition

A disc-shaped patch(es) of skin inflammation that is red, raised, and scaly; it typically develops on the face, scalp, and neck, and often leaves scars and dyspigmentation as a result of postinflammatory hyperpigmentation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiscoid Rash

Professional guidelines

PubMed

Lazaro D
Drugs Aging 2007;24(9):701-15. doi: 10.2165/00002512-200724090-00001. PMID: 17727302
Heinlen LD, McClain MT, Merrill J, Akbarali YW, Edgerton CC, Harley JB, James JA
Arthritis Rheum 2007 Jul;56(7):2344-51. doi: 10.1002/art.22665. PMID: 17599763
Kang TY, El-Sohemy A, Comelis MC, Eny KM, Bae SC
Lupus 2005;14(5):381-4. doi: 10.1191/0961203305lu2100oa. PMID: 15934438

Recent clinical studies

Etiology

Prevete I, Iuliano A, Cauli A, Piga M, Iannone F, Coladonato L, Bortoluzzi A, Silvagni E, Tani C, Elefante E, Doria A, Iaccarino L, Franceschini F, Fredi M, Conti F, Spinelli FR, Frediani B, Gonzales Garcìa E, Scirè CA, Zanetti A, Rozza D, Carrara G, Sebastiani GD; Early Lupus project
Clin Exp Rheumatol 2023 Jan;41(1):145-150. Epub 2022 Jul 26 doi: 10.55563/clinexprheumatol/oo5ymg. PMID: 35894063
Wu Q, Zhou J, Yuan ZC, Lan YY, Xu WD, Huang AF
Immunol Invest 2022 May;51(4):727-738. Epub 2021 Jan 17 doi: 10.1080/08820139.2020.1869254. PMID: 33459098
Hannon CW, McCourt C, Lima HC, Chen S, Bennett C
Cochrane Database Syst Rev 2021 Mar 9;3(3):CD007478. doi: 10.1002/14651858.CD007478.pub2. PMID: 33687069Free PMC Article
Kallas R, Goldman D, Petri MA
Lupus Sci Med 2020 Sep;7(1) doi: 10.1136/lupus-2020-000411. PMID: 32963114Free PMC Article
Babaoglu H, Li J, Goldman D, Magder LS, Petri M
Lupus 2019 Dec;28(14):1648-1655. Epub 2019 Nov 6 doi: 10.1177/0961203319886028. PMID: 31694446Free PMC Article

Diagnosis

Alduraibi FK, Sullivan KA, Chatham WW, Hsu HC, Mountz JD
Clin Immunol 2023 Feb;247:109239. Epub 2023 Jan 20 doi: 10.1016/j.clim.2023.109239. PMID: 36682593Free PMC Article
Hannon CW, McCourt C, Lima HC, Chen S, Bennett C
Cochrane Database Syst Rev 2021 Mar 9;3(3):CD007478. doi: 10.1002/14651858.CD007478.pub2. PMID: 33687069Free PMC Article
Kallas R, Goldman D, Petri MA
Lupus Sci Med 2020 Sep;7(1) doi: 10.1136/lupus-2020-000411. PMID: 32963114Free PMC Article
Stegert M, Bock M, Trendelenburg M
Mol Immunol 2015 Sep;67(1):3-11. Epub 2015 Apr 3 doi: 10.1016/j.molimm.2015.03.007. PMID: 25846716
Chiewchengchol D, Murphy R, Edwards SW, Beresford MW
Pediatr Rheumatol Online J 2015;13:1. Epub 2015 Jan 5 doi: 10.1186/1546-0096-13-1. PMID: 25587243Free PMC Article

Therapy

Lee J, Lee YJ, Kim Y
Medicine (Baltimore) 2021 Jun 4;100(22):e26238. doi: 10.1097/MD.0000000000026238. PMID: 34087909Free PMC Article
Hannon CW, McCourt C, Lima HC, Chen S, Bennett C
Cochrane Database Syst Rev 2021 Mar 9;3(3):CD007478. doi: 10.1002/14651858.CD007478.pub2. PMID: 33687069Free PMC Article
Babaoglu H, Li J, Goldman D, Magder LS, Petri M
Lupus 2019 Dec;28(14):1648-1655. Epub 2019 Nov 6 doi: 10.1177/0961203319886028. PMID: 31694446Free PMC Article
Bourré-Tessier J, Peschken CA, Bernatsky S, Joseph L, Clarke AE, Fortin PR, Hitchon C, Mittoo S, Smith CD, Zummer M, Pope J, Tucker L, Hudson M, Arbillaga H, Esdaile J, Silverman E, Chédeville G, Huber AM, Belisle P; Canadian Network for Improved Outcomes in Systemic Lupus Erythematosus 1000 Canadian Faces of Lupus Investigators, Pineau CA
Arthritis Care Res (Hoboken) 2013 Aug;65(8):1275-80. doi: 10.1002/acr.21966. PMID: 23401335
Al Arfaj AS, Khalil N
Lupus 2009 Apr;18(5):465-73. doi: 10.1177/0961203308100660. PMID: 19318403

Prognosis

Prevete I, Iuliano A, Cauli A, Piga M, Iannone F, Coladonato L, Bortoluzzi A, Silvagni E, Tani C, Elefante E, Doria A, Iaccarino L, Franceschini F, Fredi M, Conti F, Spinelli FR, Frediani B, Gonzales Garcìa E, Scirè CA, Zanetti A, Rozza D, Carrara G, Sebastiani GD; Early Lupus project
Clin Exp Rheumatol 2023 Jan;41(1):145-150. Epub 2022 Jul 26 doi: 10.55563/clinexprheumatol/oo5ymg. PMID: 35894063
Kallas R, Goldman D, Petri MA
Lupus Sci Med 2020 Sep;7(1) doi: 10.1136/lupus-2020-000411. PMID: 32963114Free PMC Article
Babaoglu H, Li J, Goldman D, Magder LS, Petri M
Lupus 2019 Dec;28(14):1648-1655. Epub 2019 Nov 6 doi: 10.1177/0961203319886028. PMID: 31694446Free PMC Article
Lhakum P, Kasitanon N, Sivasomboon C, Wangkaew S, Louthrenoo W
J Clin Rheumatol 2016 Jan;22(1):1-7. doi: 10.1097/RHU.0000000000000333. PMID: 26693619
Stegert M, Bock M, Trendelenburg M
Mol Immunol 2015 Sep;67(1):3-11. Epub 2015 Apr 3 doi: 10.1016/j.molimm.2015.03.007. PMID: 25846716

Clinical prediction guides

Kallas R, Goldman D, Petri MA
Lupus Sci Med 2020 Sep;7(1) doi: 10.1136/lupus-2020-000411. PMID: 32963114Free PMC Article
Bogaczewicz J, Tokarska K, Wozniacka A
Biomed Res Int 2019;2019:5897487. Epub 2019 Dec 24 doi: 10.1155/2019/5897487. PMID: 31930128Free PMC Article
Babaoglu H, Li J, Goldman D, Magder LS, Petri M
Lupus 2019 Dec;28(14):1648-1655. Epub 2019 Nov 6 doi: 10.1177/0961203319886028. PMID: 31694446Free PMC Article
Leng X, Li M, Li X, Zhang X, Liu S, Wu L, Ma L, Bi L, Zuo X, Sun L, Huang C, Zhao J, Zhao Y, Zeng X; CSTAR group
Clin Exp Rheumatol 2018 Jan-Feb;36(1):81-87. Epub 2017 Jul 7 PMID: 28770711
Bourré-Tessier J, Peschken CA, Bernatsky S, Joseph L, Clarke AE, Fortin PR, Hitchon C, Mittoo S, Smith CD, Zummer M, Pope J, Tucker L, Hudson M, Arbillaga H, Esdaile J, Silverman E, Chédeville G, Huber AM, Belisle P; Canadian Network for Improved Outcomes in Systemic Lupus Erythematosus 1000 Canadian Faces of Lupus Investigators, Pineau CA
Arthritis Care Res (Hoboken) 2013 Aug;65(8):1275-80. doi: 10.1002/acr.21966. PMID: 23401335

Recent systematic reviews

Hannon CW, McCourt C, Lima HC, Chen S, Bennett C
Cochrane Database Syst Rev 2021 Mar 9;3(3):CD007478. doi: 10.1002/14651858.CD007478.pub2. PMID: 33687069Free PMC Article

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