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Corpus cavernosum hypoplasia

MedGen UID:
816190
•Concept ID:
C3809860
•
Congenital Abnormality
Synonym: Hypoplasia of corpus cavernosum
 
HPO: HP:4000094

Definition

A developmental anomaly characterized by undergrowth of the corpus cavernosum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCorpus cavernosum hypoplasia

Conditions with this feature

Testicular anomalies with or without congenital heart disease
MedGen UID:
816188
•Concept ID:
C3809858
•
Disease or Syndrome
See: Condition Record
Testicular anomalies with or without congenital heart disease

Recent clinical studies

Etiology

Penile Doppler ultrasound study in priapism: A systematic review.
Wakrim S, Ziouziou I, Ralph D, Khabbal Y
Prog Urol 2022 Jan;32(1):61-69. Epub 2021 Jul 3 doi: 10.1016/j.purol.2021.03.009. PMID: 34229947
Urethral pull-up operation for distal and mid-penile hypospadias: a new safe method.
Jawale SA, Jesudian G, Nehete R
Trop Doct 2019 Jan;49(1):65-67. Epub 2018 Nov 4 doi: 10.1177/0049475518807315. PMID: 30394855
The effect of intracavernous injection of adipose tissue-derived stem cells on hyperlipidemia-associated erectile dysfunction in a rat model.
Huang YC, Ning H, Shindel AW, Fandel TM, Lin G, Harraz AM, Lue TF, Lin CS
J Sex Med 2010 Apr;7(4 Pt 1):1391-400. Epub 2010 Feb 5 doi: 10.1111/j.1743-6109.2009.01697.x. PMID: 20141586Free PMC Article
Detubularized pedicled vaginal onlay flap urethroplasty: a new method for hypospadias repair of ambiguous genitalia.
Kajbafzadeh AM, Nezami BG
J Urol 2008 Nov;180(5):2159-66. Epub 2008 Sep 20 doi: 10.1016/j.juro.2008.07.065. PMID: 18804820
MRI in the diagnosis of diphallia.
Ghafoori M, Varedi P, Hosseini SJ
Pediatr Radiol 2007 Dec;37(12):1298-300. Epub 2007 Oct 2 doi: 10.1007/s00247-007-0627-6. PMID: 17909781

Diagnosis

Penile Doppler ultrasound study in priapism: A systematic review.
Wakrim S, Ziouziou I, Ralph D, Khabbal Y
Prog Urol 2022 Jan;32(1):61-69. Epub 2021 Jul 3 doi: 10.1016/j.purol.2021.03.009. PMID: 34229947
Sexual dysfunction in diabetes.
Tamás V, Kempler P
Handb Clin Neurol 2014;126:223-32. doi: 10.1016/B978-0-444-53480-4.00017-5. PMID: 25410225
Standard operating procedures for neurophysiologic assessment of male sexual dysfunction.
Giuliano F, Rowland DL
J Sex Med 2013 May;10(5):1205-11. Epub 2013 Apr 11 doi: 10.1111/jsm.12164. PMID: 23577591
Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724

Therapy

Sexual dysfunction in diabetes.
Tamás V, Kempler P
Handb Clin Neurol 2014;126:223-32. doi: 10.1016/B978-0-444-53480-4.00017-5. PMID: 25410225
P144, A TGF-β1 antagonist peptide, synergizes with sildenafil and enhances erectile response via amelioration of cavernosal fibrosis in diabetic rats.
Li WJ, Wang H, Zhou J, Li B, Zhang J, Lu M, Wang Z
J Sex Med 2013 Dec;10(12):2942-51. Epub 2013 Oct 17 doi: 10.1111/jsm.12325. PMID: 24134744
Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201
Hormonal supplementation and erectile dysfunction.
Aversa A, Isidori AM, Greco EA, Giannetta E, Gianfrilli D, Spera E, Fabbri A
Eur Urol 2004 May;45(5):535-8. doi: 10.1016/j.eururo.2004.01.005. PMID: 15082192
Corporeal herniation after Nesbit plication with partial thickness shaving for congenital penile curvature.
Minervini A, Morelli G, Dinelli N, Selli C, Minervini R
Int J Impot Res 2003 Dec;15(6):465-7. doi: 10.1038/sj.ijir.3901037. PMID: 14671669

Prognosis

Urethral pull-up operation for distal and mid-penile hypospadias: a new safe method.
Jawale SA, Jesudian G, Nehete R
Trop Doct 2019 Jan;49(1):65-67. Epub 2018 Nov 4 doi: 10.1177/0049475518807315. PMID: 30394855
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724
Dorsal vein thrombosis of the penis presenting to an STD clinic.
Evans DT, Ward OE
Genitourin Med 1994 Dec;70(6):406-9. doi: 10.1136/sti.70.6.406. PMID: 7705859Free PMC Article
An atypical case of arising of some parietal branches of the Arteria iliaca interna in man.
Pác L, Hamplová M, Pelcová O
Anat Anz 1977;141(5):450-4. PMID: 907187
Hemihypertrophy of the human corpus cavernosum.
Fitzpatrick TJ
J Urol 1976 May;115(5):560-1. doi: 10.1016/s0022-5347(17)59282-4. PMID: 1271551

Clinical prediction guides

Diphallia: a case report of a rare anomaly evaluated by magnetic resonance imaging.
Duarte ML, Dos-Santos LR, Silva A, Silva M
Turk J Pediatr 2021;63(5):917-921. doi: 10.24953/turkjped.2021.05.021. PMID: 34738375
Fetoscopic diagnosis of congenital megalourethra at early second trimester.
Yamamoto R, Ishii K, Ukita S, Hidaka N, Kobayashi K, Shimada K, Mitsuda N
Fetal Diagn Ther 2013;34(1):63-5. Epub 2013 Mar 29 doi: 10.1159/000348773. PMID: 23548627
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724
Reconstitution of human corpus cavernosum smooth muscle in vitro and in vivo.
Kershen RT, Yoo JJ, Moreland RB, Krane RJ, Atala A
Tissue Eng 2002 Jul;8(3):515-24. doi: 10.1089/107632702760184754. PMID: 12167235
Hemihypertrophy of the human corpus cavernosum.
Fitzpatrick TJ
J Urol 1976 May;115(5):560-1. doi: 10.1016/s0022-5347(17)59282-4. PMID: 1271551

Recent systematic reviews

Penile Doppler ultrasound study in priapism: A systematic review.
Wakrim S, Ziouziou I, Ralph D, Khabbal Y
Prog Urol 2022 Jan;32(1):61-69. Epub 2021 Jul 3 doi: 10.1016/j.purol.2021.03.009. PMID: 34229947
Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201

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