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Abnormal corpus cavernosum morphology

MedGen UID:
867621
•Concept ID:
C4022009
•
Anatomical Abnormality
Synonym: Abnormality of corpus cavernosum
 
HPO: HP:0100623

Definition

A structural anomaly of the corpus cavernosum, the erectile tissue of the penis. [from HPO]

Professional guidelines

PubMed

The role of ultrasonography in the diagnosis and management of penile trauma.
Dell'Atti L
J Ultrasound 2016 Sep;19(3):161-6. Epub 2016 Jan 22 doi: 10.1007/s40477-016-0195-4. PMID: 27635160Free PMC Article

Recent clinical studies

Etiology

Urethral pull-up operation for distal and mid-penile hypospadias: a new safe method.
Jawale SA, Jesudian G, Nehete R
Trop Doct 2019 Jan;49(1):65-67. Epub 2018 Nov 4 doi: 10.1177/0049475518807315. PMID: 30394855
Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Gao L, Wu C, Fu F, You X, Ma X, Qin F, Li T, Wang R, Yuan J
J Cell Mol Med 2018 Mar;22(3):2018-2022. Epub 2017 Dec 26 doi: 10.1111/jcmm.13411. PMID: 29278308Free PMC Article
The role of ultrasonography in the diagnosis and management of penile trauma.
Dell'Atti L
J Ultrasound 2016 Sep;19(3):161-6. Epub 2016 Jan 22 doi: 10.1007/s40477-016-0195-4. PMID: 27635160Free PMC Article
Role of adenosine signaling in penile erection and erectile disorders.
Phatarpekar PV, Wen J, Xia Y
J Sex Med 2010 Nov;7(11):3553-64. doi: 10.1111/j.1743-6109.2009.01555.x. PMID: 19889148Free PMC Article
Complete penile disassembly for epispadias repair: the Mitchell technique.
Mitchell ME, Bägli DJ
J Urol 1996 Jan;155(1):300-4. PMID: 7490875

Diagnosis

The role of ultrasonography in the diagnosis and management of penile trauma.
Dell'Atti L
J Ultrasound 2016 Sep;19(3):161-6. Epub 2016 Jan 22 doi: 10.1007/s40477-016-0195-4. PMID: 27635160Free PMC Article
Standard operating procedures for neurophysiologic assessment of male sexual dysfunction.
Giuliano F, Rowland DL
J Sex Med 2013 May;10(5):1205-11. Epub 2013 Apr 11 doi: 10.1111/jsm.12164. PMID: 23577591
Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724
Role of adenosine signaling in penile erection and erectile disorders.
Phatarpekar PV, Wen J, Xia Y
J Sex Med 2010 Nov;7(11):3553-64. doi: 10.1111/j.1743-6109.2009.01555.x. PMID: 19889148Free PMC Article

Therapy

Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Gao L, Wu C, Fu F, You X, Ma X, Qin F, Li T, Wang R, Yuan J
J Cell Mol Med 2018 Mar;22(3):2018-2022. Epub 2017 Dec 26 doi: 10.1111/jcmm.13411. PMID: 29278308Free PMC Article
P144, A TGF-β1 antagonist peptide, synergizes with sildenafil and enhances erectile response via amelioration of cavernosal fibrosis in diabetic rats.
Li WJ, Wang H, Zhou J, Li B, Zhang J, Lu M, Wang Z
J Sex Med 2013 Dec;10(12):2942-51. Epub 2013 Oct 17 doi: 10.1111/jsm.12325. PMID: 24134744
Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201
5alpha-reductase activity in the prostate.
Steers WD
Urology 2001 Dec;58(6 Suppl 1):17-24; discussion 24. doi: 10.1016/s0090-4295(01)01299-7. PMID: 11750244
Dynamic echography of the penis in the follow-up of impotent patients treated with intracavernous injections.
Virag R, Nollet F, Greco E, Shoukry K
Br J Urol 1993 Nov;72(5 Pt 2):809-16. doi: 10.1111/j.1464-410x.1993.tb16272.x. PMID: 8281415

Prognosis

Urethral pull-up operation for distal and mid-penile hypospadias: a new safe method.
Jawale SA, Jesudian G, Nehete R
Trop Doct 2019 Jan;49(1):65-67. Epub 2018 Nov 4 doi: 10.1177/0049475518807315. PMID: 30394855
The role of ultrasonography in the diagnosis and management of penile trauma.
Dell'Atti L
J Ultrasound 2016 Sep;19(3):161-6. Epub 2016 Jan 22 doi: 10.1007/s40477-016-0195-4. PMID: 27635160Free PMC Article
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724
Detubularized pedicled vaginal onlay flap urethroplasty: a new method for hypospadias repair of ambiguous genitalia.
Kajbafzadeh AM, Nezami BG
J Urol 2008 Nov;180(5):2159-66. Epub 2008 Sep 20 doi: 10.1016/j.juro.2008.07.065. PMID: 18804820
Complete penile disassembly for epispadias repair: the Mitchell technique.
Mitchell ME, Bägli DJ
J Urol 1996 Jan;155(1):300-4. PMID: 7490875

Clinical prediction guides

Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Gao L, Wu C, Fu F, You X, Ma X, Qin F, Li T, Wang R, Yuan J
J Cell Mol Med 2018 Mar;22(3):2018-2022. Epub 2017 Dec 26 doi: 10.1111/jcmm.13411. PMID: 29278308Free PMC Article
The role of ultrasonography in the diagnosis and management of penile trauma.
Dell'Atti L
J Ultrasound 2016 Sep;19(3):161-6. Epub 2016 Jan 22 doi: 10.1007/s40477-016-0195-4. PMID: 27635160Free PMC Article
Radiological anatomy of prostatic arteries.
Bilhim T, Tinto HR, Fernandes L, Martins Pisco J
Tech Vasc Interv Radiol 2012 Dec;15(4):276-85. doi: 10.1053/j.tvir.2012.09.006. PMID: 23244724
Reconstitution of human corpus cavernosum smooth muscle in vitro and in vivo.
Kershen RT, Yoo JJ, Moreland RB, Krane RJ, Atala A
Tissue Eng 2002 Jul;8(3):515-24. doi: 10.1089/107632702760184754. PMID: 12167235
Sequential penile ultrasound monitoring of patients treated with chronic intracavernous prostaglandin E1.
Hirsch IH, Schanne FJ, Carsello J, Bagley DH, Alexander AA
Urology 1995 Jun;45(6):1037-41. doi: 10.1016/s0090-4295(99)80127-7. PMID: 7771005

Recent systematic reviews

Idiopathic partial thrombosis of the corpus cavernosum: aetiology, diagnosis and treatment.
Hulth M, Albersen M, Fode M, Peeters K, Ramskov KL, Joniau S, Bisbjerg R, Sønksen J
Scand J Urol 2013 Apr;47(2):163-8. Epub 2012 Jul 5 doi: 10.3109/00365599.2012.698305. PMID: 22762201

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