U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Branch Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

MedGen UID:
819638
•Concept ID:
C3826890
•
Neoplastic Process
Synonyms: Pancreatic BD-IPMN; Pancreatic SB-IPMN; Side Branch Pancreatic Intraductal Papillary-Mucinous Neoplasm

Definition

An intraductal papillary-mucinous neoplasm of the pancreas that arises in one of the branches of the main pancreatic duct. It usually has an indolent behavior. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBranch Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

Professional guidelines

PubMed

Evaluation of the guidelines for management of pancreatic branch-duct intraductal papillary mucinous neoplasm.
Tang RS, Weinberg B, Dawson DW, Reber H, Hines OJ, Tomlinson JS, Chaudhari V, Raman S, Farrell JJ
Clin Gastroenterol Hepatol 2008 Jul;6(7):815-9; quiz 719. doi: 10.1016/j.cgh.2008.04.005. PMID: 18602036

Recent clinical studies

Etiology

Long-Term Outcomes and Risk of Pancreatic Cancer in Intraductal Papillary Mucinous Neoplasms.
de la Fuente J, Chatterjee A, Lui J, Nehra AK, Bell MG, Lennon RJ, Kassmeyer BA, Graham RP, Nagayama H, Schulte PJ, Doering KA, Delgado AM, Vege SS, Chari ST, Takahashi N, Majumder S
JAMA Netw Open 2023 Oct 2;6(10):e2337799. doi: 10.1001/jamanetworkopen.2023.37799. PMID: 37847503Free PMC Article
Surgical strategy for intraductal papillary mucinous neoplasms of the pancreas.
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Current Guideline Controversies in the Management of Pancreatic Cystic Neoplasms.
DiMaio CJ
Gastrointest Endosc Clin N Am 2018 Oct;28(4):529-547. Epub 2018 Aug 1 doi: 10.1016/j.giec.2018.05.005. PMID: 30241642
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806
Treatment of pancreatic cystic neoplasm: surgery or conservative?
Talukdar R, Nageshwar Reddy D
Clin Gastroenterol Hepatol 2014 Jan;12(1):145-51. Epub 2013 Aug 24 doi: 10.1016/j.cgh.2013.08.031. PMID: 23978346

Diagnosis

Optimal Surveillance Interval of Branch Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas.
Han Y, Kwon W, Lee M, Jung HS, Yun WG, Cho YJ, Chae YS, Fernández-Del Castillo C, Marchegiani G, Salvia R, Goh BKP, Lee WJ, Jang JY
JAMA Surg 2024 Apr 1;159(4):389-396. doi: 10.1001/jamasurg.2023.7010. PMID: 38231494Free PMC Article
Long-Term Outcomes and Risk of Pancreatic Cancer in Intraductal Papillary Mucinous Neoplasms.
de la Fuente J, Chatterjee A, Lui J, Nehra AK, Bell MG, Lennon RJ, Kassmeyer BA, Graham RP, Nagayama H, Schulte PJ, Doering KA, Delgado AM, Vege SS, Chari ST, Takahashi N, Majumder S
JAMA Netw Open 2023 Oct 2;6(10):e2337799. doi: 10.1001/jamanetworkopen.2023.37799. PMID: 37847503Free PMC Article
Surgical strategy for intraductal papillary mucinous neoplasms of the pancreas.
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Current Guideline Controversies in the Management of Pancreatic Cystic Neoplasms.
DiMaio CJ
Gastrointest Endosc Clin N Am 2018 Oct;28(4):529-547. Epub 2018 Aug 1 doi: 10.1016/j.giec.2018.05.005. PMID: 30241642
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806

Therapy

Long-Term Outcomes and Risk of Pancreatic Cancer in Intraductal Papillary Mucinous Neoplasms.
de la Fuente J, Chatterjee A, Lui J, Nehra AK, Bell MG, Lennon RJ, Kassmeyer BA, Graham RP, Nagayama H, Schulte PJ, Doering KA, Delgado AM, Vege SS, Chari ST, Takahashi N, Majumder S
JAMA Netw Open 2023 Oct 2;6(10):e2337799. doi: 10.1001/jamanetworkopen.2023.37799. PMID: 37847503Free PMC Article
Pancreatic cancer detection with a non-contrast MR protocol: is it reliable?
Maio F, Pasqualino V, Bertana L, Venturini S, Cantoni V, Fusaro M, Morana G
Radiol Med 2023 Sep;128(9):1035-1046. Epub 2023 Jul 29 doi: 10.1007/s11547-023-01680-z. PMID: 37515631Free PMC Article
Enucleation for branch duct intraductal papillary mucinous neoplasms: a systematic review and meta-analysis.
Ratnayake CB, Biela C, Windsor JA, Pandanaboyana S
HPB (Oxford) 2019 Dec;21(12):1593-1602. Epub 2019 May 29 doi: 10.1016/j.hpb.2019.04.015. PMID: 31153837
Surveillance and Outcomes of Nonresected Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms: A Meta-analysis.
Ooka K, Rustagi T, Evans A, Farrell JJ
Pancreas 2017 Aug;46(7):927-935. doi: 10.1097/MPA.0000000000000858. PMID: 28697134
Secretin-enhanced MR cholangiopancreatography: spectrum of findings.
Tirkes T, Sandrasegaran K, Sanyal R, Sherman S, Schmidt CM, Cote GA, Akisik F
Radiographics 2013 Nov-Dec;33(7):1889-906. doi: 10.1148/rg.337125014. PMID: 24224585

Prognosis

Surgical strategy for intraductal papillary mucinous neoplasms of the pancreas.
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Development and Validation of a Multi-institutional Preoperative Nomogram for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas: A Report from The Pancreatic Surgery Consortium.
Attiyeh MA, Fernández-Del Castillo C, Al Efishat M, Eaton AA, Gönen M, Batts R, Pergolini I, Rezaee N, Lillemoe KD, Ferrone CR, Mino-Kenudson M, Weiss MJ, Cameron JL, Hruban RH, D'Angelica MI, DeMatteo RP, Kingham TP, Jarnagin WR, Wolfgang CL, Allen PJ
Ann Surg 2018 Jan;267(1):157-163. doi: 10.1097/SLA.0000000000002015. PMID: 28079542Free PMC Article
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806
Pancreatic intraductal papillary mucinous neoplasm--where is the challenge?
Fritz S, Hackert T, Büchler MW
Dig Dis 2015;33(1):99-105. Epub 2014 Dec 17 doi: 10.1159/000368448. PMID: 25531503
IPMN: surgical treatment.
Käppeli RM, Müller SA, Hummel B, Kruse C, Müller P, Fornaro J, Wilhelm A, Zadnikar M, Schmied BM, Tarantino I
Langenbecks Arch Surg 2013 Dec;398(8):1029-37. Epub 2013 Sep 3 doi: 10.1007/s00423-013-1106-1. PMID: 23999775

Clinical prediction guides

Management Algorithms for Pancreatic Cystic Neoplasms.
Kim HS, Jang JY
Arch Pathol Lab Med 2022 Mar 1;146(3):322-329. doi: 10.5858/arpa.2020-0395-RA. PMID: 33503225
Surgical strategy for intraductal papillary mucinous neoplasms of the pancreas.
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Development and Validation of a Multi-institutional Preoperative Nomogram for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas: A Report from The Pancreatic Surgery Consortium.
Attiyeh MA, Fernández-Del Castillo C, Al Efishat M, Eaton AA, Gönen M, Batts R, Pergolini I, Rezaee N, Lillemoe KD, Ferrone CR, Mino-Kenudson M, Weiss MJ, Cameron JL, Hruban RH, D'Angelica MI, DeMatteo RP, Kingham TP, Jarnagin WR, Wolfgang CL, Allen PJ
Ann Surg 2018 Jan;267(1):157-163. doi: 10.1097/SLA.0000000000002015. PMID: 28079542Free PMC Article
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806
Pancreatic intraductal papillary mucinous neoplasm--where is the challenge?
Fritz S, Hackert T, Büchler MW
Dig Dis 2015;33(1):99-105. Epub 2014 Dec 17 doi: 10.1159/000368448. PMID: 25531503

Recent systematic reviews

Systematic review on surveillance for non-resected branch-duct intraductal papillary mucinous neoplasms of the pancreas.
Kazmi SZ, Jung HS, Han Y, Yun WG, Cho YJ, Lee M, Kwon W, Castillo CF, Del Chiaro M, Marchegiani G, Goh BKP, Hijioka S, Majumder S, Nakai Y, Shin A, Jang JY
Pancreatology 2024 May;24(3):463-488. Epub 2024 Feb 28 doi: 10.1016/j.pan.2024.02.015. PMID: 38480047
Intraductal tubulopapillary neoplasm (ITPN) of the pancreas: a distinct entity among pancreatic tumors.
Paolino G, Esposito I, Hong SM, Basturk O, Mattiolo P, Kaneko T, Veronese N, Scarpa A, Adsay V, Luchini C
Histopathology 2022 Sep;81(3):297-309. Epub 2022 May 27 doi: 10.1111/his.14698. PMID: 35583805Free PMC Article
Association between pancreatic intraductal papillary mucinous neoplasms and extrapancreatic malignancies: A systematic review with meta-analysis.
Facciorusso A, Crinò SF, Ramai D, Marchegiani G, Lester J, Singh J, Lisotti A, Fusaroli P, Cannizzaro R, Gkolfakis P, Papanikolaou IS, Triantafyllou K, Singh S
Eur J Surg Oncol 2022 Mar;48(3):632-639. Epub 2021 Oct 1 doi: 10.1016/j.ejso.2021.09.018. PMID: 34620511
Imaging Features for Predicting High-Grade Dysplasia or Malignancy in Branch Duct Type Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Systematic Review and Meta-Analysis.
Zhao W, Liu S, Cong L, Zhao Y
Ann Surg Oncol 2022 Feb;29(2):1297-1312. Epub 2021 Sep 23 doi: 10.1245/s10434-021-10662-2. PMID: 34554343
Surveillance and Outcomes of Nonresected Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms: A Meta-analysis.
Ooka K, Rustagi T, Evans A, Farrell JJ
Pancreas 2017 Aug;46(7):927-935. doi: 10.1097/MPA.0000000000000858. PMID: 28697134

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...