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t(9;11)

MedGen UID:
820618
Concept ID:
C3827870
Cell or Molecular Dysfunction

Definition

A translocation between chromosome 9 and chromosome 11. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(9;11)

Professional guidelines

PubMed

Liu L, Feng GS, Gao H, Tong GS, Wang Y, Gao W, Huang Y, Li C
World J Gastroenterol 2005 Apr 14;11(14):2101-8. doi: 10.3748/wjg.v11.i14.2101. PMID: 15810075Free PMC Article
Metzler M, Strissel PL, Strick R, Niemeyer C, Roettgers S, Borkhardt A, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Reinhardt D, Creutzig U, Beck JD, Rascher W, Repp R, Langer T
Genes Chromosomes Cancer 2004 Nov;41(3):291-6. doi: 10.1002/gcc.20083. PMID: 15334554
Leone G, Voso MT, Sica S, Morosetti R, Pagano L
Leuk Lymphoma 2001 Apr;41(3-4):255-76. doi: 10.3109/10428190109057981. PMID: 11378539

Recent clinical studies

Etiology

Sparavier A, Di Croce L
Curr Opin Genet Dev 2022 Aug;75:101920. Epub 2022 May 21 doi: 10.1016/j.gde.2022.101920. PMID: 35609423
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD
Proc Natl Acad Sci U S A 2020 Oct 20;117(42):26340-26346. Epub 2020 Oct 5 doi: 10.1073/pnas.2014732117. PMID: 33020282Free PMC Article
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Okamoto Y, Ribeiro RC, Srivastava DK, Shenep JL, Pui CH, Razzouk BI
J Pediatr Hematol Oncol 2003 Sep;25(9):696-703. doi: 10.1097/00043426-200309000-00005. PMID: 12972804
Leone G, Voso MT, Sica S, Morosetti R, Pagano L
Leuk Lymphoma 2001 Apr;41(3-4):255-76. doi: 10.3109/10428190109057981. PMID: 11378539

Diagnosis

Zou YS, Morsberger L, Hardy M, Ghabrial J, Stinnett V, Murry JB, Long P, Kim A, Pratilas CA, Llosa NJ, Ladle BH, Lemberg KM, Levin AS, Morris CD, Haley L, Gocke CD, Gross JM
Genes (Basel) 2023 May 24;14(6) doi: 10.3390/genes14061139. PMID: 37372318Free PMC Article
Laursen AC, Sandahl JD, Kjeldsen E, Abrahamsson J, Asdahl P, Ha SY, Heldrup J, Jahnukainen K, Jónsson ÓG, Lausen B, Palle J, Zeller B, Forestier E, Hasle H
Genes Chromosomes Cancer 2016 Sep;55(9):719-26. Epub 2016 Jun 23 doi: 10.1002/gcc.22373. PMID: 27153159
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Thalhammer-Scherrer R, Wieselthaler G, Knoebl P, Schwarzinger I, Simonitsch I, Mitterbauer G, Berlakovich GA, Mannhalter C, Haas OA, Mayer G, Muehlbacher F, Wolner E, Klepetko W, Lechner K, Jaeger U
Leukemia 1999 Mar;13(3):321-6. doi: 10.1038/sj.leu.2401301. PMID: 10086721
Chan GC, Wang WC, Raimondi SC, Behm FG, Krance RA, Chen G, Freiberg A, Ingram L, Butler D, Head DR
Leukemia 1997 Feb;11(2):206-11. doi: 10.1038/sj.leu.2400558. PMID: 9009082

Therapy

Andreieva SV, Kyselova OA, Serbin IM, Alkhimova OG
Exp Oncol 2020 Jun;42(2):126-129. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-2.14593. PMID: 32602288
Harrison CJ, Hills RK, Moorman AV, Grimwade DJ, Hann I, Webb DK, Wheatley K, de Graaf SS, van den Berg E, Burnett AK, Gibson BE
J Clin Oncol 2010 Jun 1;28(16):2674-81. Epub 2010 May 3 doi: 10.1200/JCO.2009.24.8997. PMID: 20439644
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Thalhammer-Scherrer R, Wieselthaler G, Knoebl P, Schwarzinger I, Simonitsch I, Mitterbauer G, Berlakovich GA, Mannhalter C, Haas OA, Mayer G, Muehlbacher F, Wolner E, Klepetko W, Lechner K, Jaeger U
Leukemia 1999 Mar;13(3):321-6. doi: 10.1038/sj.leu.2401301. PMID: 10086721
Lambertenghi Deliliers G, Annaloro C, Pozzoli E, Oriani A, Della Volpe A, Soligo D, Lambertenghi Deliliers D, Tagliaferri E, Bertolli V, Romitti L
Leuk Res 1999 Mar;23(3):291-7. doi: 10.1016/s0145-2126(98)00139-8. PMID: 10071084

Prognosis

Sparavier A, Di Croce L
Curr Opin Genet Dev 2022 Aug;75:101920. Epub 2022 May 21 doi: 10.1016/j.gde.2022.101920. PMID: 35609423
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD
Proc Natl Acad Sci U S A 2020 Oct 20;117(42):26340-26346. Epub 2020 Oct 5 doi: 10.1073/pnas.2014732117. PMID: 33020282Free PMC Article
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA
Nature 2006 Aug 17;442(7104):818-22. Epub 2006 Jul 16 doi: 10.1038/nature04980. PMID: 16862118
Chan GC, Wang WC, Raimondi SC, Behm FG, Krance RA, Chen G, Freiberg A, Ingram L, Butler D, Head DR
Leukemia 1997 Feb;11(2):206-11. doi: 10.1038/sj.leu.2400558. PMID: 9009082

Clinical prediction guides

Russon J, Morrissey J, Dellinger J, Jin B, Diamond G
Crisis 2022 Dec;43(6):500-507. Epub 2021 Sep 14 doi: 10.1027/0227-5910/a000821. PMID: 34519544
Young K, Loberg MA, Eudy E, Schwartz LS, Mujica KD, Trowbridge JJ
Exp Hematol 2020 Sep;89:61-67.e3. Epub 2020 Aug 6 doi: 10.1016/j.exphem.2020.07.012. PMID: 32768438Free PMC Article
Creutzig U, Zimmermann M, Reinhardt D, Rasche M, von Neuhoff C, Alpermann T, Dworzak M, Perglerová K, Zemanova Z, Tchinda J, Bradtke J, Thiede C, Haferlach C
Cancer 2016 Dec 15;122(24):3821-3830. Epub 2016 Aug 16 doi: 10.1002/cncr.30220. PMID: 27529519
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Wuchter C, Ratei R, Spahn G, Schoch C, Harbott J, Schnittger S, Haferlach T, Creutzig U, Sperling C, Karawajew L, Ludwig WD
Haematologica 2001 Feb;86(2):154-61. PMID: 11224484

Recent systematic reviews

Hidalgo-Gómez G, Palacio-Garcia C, Gallur L, Blanco A, Tazón-Vega B, Saumell S, Martínez N, Murillo L, Murciano T, Velasco P, Bosch F, Diaz-Heredia C, Ortega M
Leuk Lymphoma 2021 Sep;62(9):2202-2210. Epub 2021 Apr 7 doi: 10.1080/10428194.2021.1907375. PMID: 33827367

Supplemental Content

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