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Drug Induced Cutaneous Lupus Erythematosus

MedGen UID:
823139
•Concept ID:
C3830391
•
Disease or Syndrome

Definition

A reaction to a drug characterized by skin findings common to lupus including photosensitivity and butterfly rash; typically it resolves after drug discontinuation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDrug Induced Cutaneous Lupus Erythematosus

Professional guidelines

PubMed

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Recent Developments in the Diagnosis and Management of Photosensitive Disorders.
Nahhas AF, Oberlin DM, Braunberger TL, Lim HW
Am J Clin Dermatol 2018 Oct;19(5):707-731. doi: 10.1007/s40257-018-0365-6. PMID: 29959757
Cutaneous lupus erythematosus: issues in diagnosis and treatment.
Walling HW, Sontheimer RD
Am J Clin Dermatol 2009;10(6):365-81. doi: 10.2165/11310780-000000000-00000. PMID: 19824738

Recent clinical studies

Etiology

Drug-induced cutaneous lupus erythematosus: 88 new cases.
Laurinaviciene R, Sandholdt LH, Bygum A
Eur J Dermatol 2017 Feb 1;27(1):28-33. doi: 10.1684/ejd.2016.2912. PMID: 27799135

Diagnosis

Anticancer treatments and photosensitivity.
Sibaud V
J Eur Acad Dermatol Venereol 2022 Jun;36 Suppl 6(Suppl 6):51-58. doi: 10.1111/jdv.18200. PMID: 35738806Free PMC Article
Drug-Induced Cutaneous Lupus Erythematosus: A Case Series of Five Patients with Bupropion-Associated Disease.
Hannah CE, Little AJ, Wanat KA, Fairley JA
J Clin Rheumatol 2021 Jun 1;27(4):e125-e128. doi: 10.1097/RHU.0000000000000882. PMID: 30222626
Drug-induced cutaneous lupus erythematosus after immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy: a case series.
Adrichem ME, Starink MV, van Leeuwen EMM, Kramer C, van Schaik IN, Eftimov F
J Peripher Nerv Syst 2017 Sep;22(3):213-218. doi: 10.1111/jns.12218. PMID: 28480635
Drug-induced cutaneous lupus erythematosus: 88 new cases.
Laurinaviciene R, Sandholdt LH, Bygum A
Eur J Dermatol 2017 Feb 1;27(1):28-33. doi: 10.1684/ejd.2016.2912. PMID: 27799135
Drug-induced cutaneous lupus erythematosus, a distinct syndrome that is frequently unrecognized.
Callen JP
J Am Acad Dermatol 2001 Aug;45(2):315-6. doi: 10.1067/mjd.2001.116583. PMID: 11464200

Therapy

Drug-Induced Cutaneous Lupus Erythematosus: A Case Series of Five Patients with Bupropion-Associated Disease.
Hannah CE, Little AJ, Wanat KA, Fairley JA
J Clin Rheumatol 2021 Jun 1;27(4):e125-e128. doi: 10.1097/RHU.0000000000000882. PMID: 30222626
Drug-induced cutaneous lupus erythematosus after immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy: a case series.
Adrichem ME, Starink MV, van Leeuwen EMM, Kramer C, van Schaik IN, Eftimov F
J Peripher Nerv Syst 2017 Sep;22(3):213-218. doi: 10.1111/jns.12218. PMID: 28480635
Drug-induced cutaneous lupus erythematosus: 88 new cases.
Laurinaviciene R, Sandholdt LH, Bygum A
Eur J Dermatol 2017 Feb 1;27(1):28-33. doi: 10.1684/ejd.2016.2912. PMID: 27799135
Drug-induced cutaneous lupus erythematosus after 5 years of treatment with carbamazepine.
Amerio P, Innocente C, Feliciani C, Angelucci D, Gambi D, Tulli A
Eur J Dermatol 2006 May-Jun;16(3):281-3. PMID: 16709494
Drug-induced cutaneous lupus erythematosus, a distinct syndrome that is frequently unrecognized.
Callen JP
J Am Acad Dermatol 2001 Aug;45(2):315-6. doi: 10.1067/mjd.2001.116583. PMID: 11464200

Clinical prediction guides

Anticancer treatments and photosensitivity.
Sibaud V
J Eur Acad Dermatol Venereol 2022 Jun;36 Suppl 6(Suppl 6):51-58. doi: 10.1111/jdv.18200. PMID: 35738806Free PMC Article

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