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Primary eosinophilic endomyocardial restrictive cardiomyopathy

MedGen UID:
82684
•Concept ID:
C0264834
•
Disease or Syndrome
Synonyms: Constrictive endocarditis; Eosinophilic endomyocardial disease; Eosinophilic Endomyocardial Disease; Löffler's endocarditis; Löffler's parietal fibroplastic endocarditis
SNOMED CT: Primary eosinophilic endomyocardial restrictive cardiomyopathy (33258008); Eosinophilic endomyocardial disease (33258008); Löffler's endocarditis (33258008); Constrictive endocarditis (33258008); Löffler's parietal fibroplastic endocarditis (33258008)

Definition

A disorder characterised by persistent eosinophilia and acute endocardial lesions, which may progress to endomyocardial fibrosis; most cases are idopathic, but there is some association with malignant tumors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary eosinophilic endomyocardial restrictive cardiomyopathy

Recent clinical studies

Etiology

Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler's endocarditis: a case report.
Gastl M, Behm P, Jacoby C, Kelm M, Bönner F
BMC Cardiovasc Disord 2017 Mar 11;17(1):74. doi: 10.1186/s12872-017-0492-7. PMID: 28284183Free PMC Article

Diagnosis

Clinical perspective on the myocarditis and cardiomyopathies.
Štěchovský C, Adla T, Bonaventura J
Cesk Patol 2019 Fall;55(4):209-217. PMID: 31842551
Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler's endocarditis: a case report.
Gastl M, Behm P, Jacoby C, Kelm M, Bönner F
BMC Cardiovasc Disord 2017 Mar 11;17(1):74. doi: 10.1186/s12872-017-0492-7. PMID: 28284183Free PMC Article
Low frequency of detection by nested polymerase chain reaction of enterovirus ribonucleic acid in endomyocardial tissue of patients with idiopathic dilated cardiomyopathy.
Giacca M, Severini GM, Mestroni L, Salvi A, Lardieri G, Falaschi A, Camerini F
J Am Coll Cardiol 1994 Oct;24(4):1033-40. doi: 10.1016/0735-1097(94)90866-4. PMID: 7930194

Therapy

Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler's endocarditis: a case report.
Gastl M, Behm P, Jacoby C, Kelm M, Bönner F
BMC Cardiovasc Disord 2017 Mar 11;17(1):74. doi: 10.1186/s12872-017-0492-7. PMID: 28284183Free PMC Article
Low frequency of detection by nested polymerase chain reaction of enterovirus ribonucleic acid in endomyocardial tissue of patients with idiopathic dilated cardiomyopathy.
Giacca M, Severini GM, Mestroni L, Salvi A, Lardieri G, Falaschi A, Camerini F
J Am Coll Cardiol 1994 Oct;24(4):1033-40. doi: 10.1016/0735-1097(94)90866-4. PMID: 7930194

Prognosis

Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler's endocarditis: a case report.
Gastl M, Behm P, Jacoby C, Kelm M, Bönner F
BMC Cardiovasc Disord 2017 Mar 11;17(1):74. doi: 10.1186/s12872-017-0492-7. PMID: 28284183Free PMC Article

Clinical prediction guides

Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler's endocarditis: a case report.
Gastl M, Behm P, Jacoby C, Kelm M, Bönner F
BMC Cardiovasc Disord 2017 Mar 11;17(1):74. doi: 10.1186/s12872-017-0492-7. PMID: 28284183Free PMC Article

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