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Subclinical infection

MedGen UID:
82906
Concept ID:
C0275522
Disease or Syndrome
Synonyms: Asymptomatic Infection; Asymptomatic Infections; Inapparent Infection; Inapparent Infections; Infection, Asymptomatic; Infection, Inapparent; Infection, Subclinical; Subclinical Infection; Subclinical Infections
SNOMED CT: Subclinical infection (28456004)

Definition

Infection associated with no detectable symptoms but caused by microorganisms capable of producing easily recognizable diseases, such a poliomyelitis or mumps. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubclinical infection

Professional guidelines

PubMed

Kar P, Sengupta A
Expert Rev Gastroenterol Hepatol 2019 Mar;13(3):205-211. Epub 2019 Jan 24 doi: 10.1080/17474124.2019.1568869. PMID: 30791760
Kohlhoff SA, Hammerschlag MR
Expert Opin Pharmacother 2015 Feb;16(2):205-12. doi: 10.1517/14656566.2015.999041. PMID: 25579069
Hammerschlag MR, Kohlhoff SA
Expert Opin Pharmacother 2012 Mar;13(4):545-52. Epub 2012 Feb 9 doi: 10.1517/14656566.2012.658776. PMID: 22316336

Recent clinical studies

Etiology

Egan K, Hook LM, LaTourette P, Desmond A, Awasthi S, Friedman HM
Transl Res 2020 Jun;220:138-152. Epub 2020 Mar 16 doi: 10.1016/j.trsl.2020.03.004. PMID: 32272093Free PMC Article
Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Shane AL, Sánchez PJ, Stoll BJ
Lancet 2017 Oct 14;390(10104):1770-1780. Epub 2017 Apr 20 doi: 10.1016/S0140-6736(17)31002-4. PMID: 28434651
Martina BE, Koraka P, Osterhaus AD
Clin Microbiol Rev 2009 Oct;22(4):564-81. doi: 10.1128/CMR.00035-09. PMID: 19822889Free PMC Article
Heyworth B, Ropp ME, Voos UG, Meinel HI, Darlow HM
Br Med J 1975 Oct 11;4(5988):79-82. doi: 10.1136/bmj.4.5988.79. PMID: 810213Free PMC Article

Diagnosis

Verma V, Goyal M, Kala D, Gupta S, Kumar D, Kaushal A
Front Biosci (Landmark Ed) 2020 Mar 1;25(9):1655-1681. doi: 10.2741/4872. PMID: 32114449
Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Knight R
Prog Mol Biol Transl Sci 2017;150:293-318. Epub 2017 Aug 14 doi: 10.1016/bs.pmbts.2017.06.010. PMID: 28838665
Shane AL, Sánchez PJ, Stoll BJ
Lancet 2017 Oct 14;390(10104):1770-1780. Epub 2017 Apr 20 doi: 10.1016/S0140-6736(17)31002-4. PMID: 28434651
Kohlhoff SA, Hammerschlag MR
Expert Opin Pharmacother 2015 Feb;16(2):205-12. doi: 10.1517/14656566.2015.999041. PMID: 25579069

Therapy

Egan K, Hook LM, LaTourette P, Desmond A, Awasthi S, Friedman HM
Transl Res 2020 Jun;220:138-152. Epub 2020 Mar 16 doi: 10.1016/j.trsl.2020.03.004. PMID: 32272093Free PMC Article
Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Kar P, Sengupta A
Expert Rev Gastroenterol Hepatol 2019 Mar;13(3):205-211. Epub 2019 Jan 24 doi: 10.1080/17474124.2019.1568869. PMID: 30791760
Shane AL, Sánchez PJ, Stoll BJ
Lancet 2017 Oct 14;390(10104):1770-1780. Epub 2017 Apr 20 doi: 10.1016/S0140-6736(17)31002-4. PMID: 28434651
Kohlhoff SA, Hammerschlag MR
Expert Opin Pharmacother 2015 Feb;16(2):205-12. doi: 10.1517/14656566.2015.999041. PMID: 25579069

Prognosis

Egan K, Hook LM, LaTourette P, Desmond A, Awasthi S, Friedman HM
Transl Res 2020 Jun;220:138-152. Epub 2020 Mar 16 doi: 10.1016/j.trsl.2020.03.004. PMID: 32272093Free PMC Article
Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Shane AL, Sánchez PJ, Stoll BJ
Lancet 2017 Oct 14;390(10104):1770-1780. Epub 2017 Apr 20 doi: 10.1016/S0140-6736(17)31002-4. PMID: 28434651
Kenyon S, Boulvain M, Neilson JP
Cochrane Database Syst Rev 2013 Dec 2;(12):CD001058. doi: 10.1002/14651858.CD001058.pub3. PMID: 24297389
Duffy DM
Adv Dermatol 1990;5:93-107; discussion 108-9. PMID: 2204381

Clinical prediction guides

Egan K, Hook LM, LaTourette P, Desmond A, Awasthi S, Friedman HM
Transl Res 2020 Jun;220:138-152. Epub 2020 Mar 16 doi: 10.1016/j.trsl.2020.03.004. PMID: 32272093Free PMC Article
Murakami I, Wada N, Nakashima J, Iguchi M, Toi M, Hashida Y, Higuchi T, Daibata M, Matsushita M, Iwasaki T, Kuwamoto S, Horie Y, Nagata K, Hayashi K, Oka T, Yoshino T, Imamura T, Morimoto A, Imashuku S, Gogusev J, Jaubert F
Cell Commun Signal 2018 Aug 22;16(1):49. doi: 10.1186/s12964-018-0261-y. PMID: 30134914Free PMC Article
Shane AL, Sánchez PJ, Stoll BJ
Lancet 2017 Oct 14;390(10104):1770-1780. Epub 2017 Apr 20 doi: 10.1016/S0140-6736(17)31002-4. PMID: 28434651
Meya DB, Manabe YC, Boulware DR, Janoff EN
Curr Opin Infect Dis 2016 Feb;29(1):10-22. doi: 10.1097/QCO.0000000000000224. PMID: 26658650Free PMC Article
Duffy DM
Adv Dermatol 1990;5:93-107; discussion 108-9. PMID: 2204381

Recent systematic reviews

Kenyon S, Boulvain M, Neilson JP
Cochrane Database Syst Rev 2013 Dec 2;(12):CD001058. doi: 10.1002/14651858.CD001058.pub3. PMID: 24297389
Kenyon S, Boulvain M, Neilson JP
Cochrane Database Syst Rev 2010 Aug 4;(8):CD001058. doi: 10.1002/14651858.CD001058.pub2. PMID: 20687063
Kenyon S, Boulvain M, Neilson J
Cochrane Database Syst Rev 2003;(2):CD001058. doi: 10.1002/14651858.CD001058. PMID: 12804398
King J, Flenady V
Cochrane Database Syst Rev 2002;(4):CD000246. doi: 10.1002/14651858.CD000246. PMID: 12519538
Kenyon S, Boulvain M, Neilson J
Cochrane Database Syst Rev 2001;(4):CD001058. doi: 10.1002/14651858.CD001058. PMID: 11687090

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