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Complex Odontoma

MedGen UID:
83166
Concept ID:
C0334563
Neoplastic Process
Synonyms: Complex odontoma; Complex odontome
SNOMED CT: Complex odontoma (29020002); Complex odontome (29020002)

Definition

A benign, slow growing, and painless hamartomatous tumor occurring in tooth-bearing areas of the jaws. It is one of the most common odontogenic tumors and it usually affects children, adolescents, and young adults. It is characterized by the presence of enamel and dentin and the absence of tooth-like structures. It is treated with local excision. If it is incompletely removed, it may recur. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplex Odontoma

Professional guidelines

PubMed

Boffano P, Cavarra F, Brucoli M, Ruslin M, Forouzanfar T, Ridwan-Pramana A, Rodríguez-Santamarta T, de Vicente JC, Starch-Jensen T, Pechalova P, Pavlov N, Doykova I, Konstantinovic VS, Jezdić Z, Barrabé A, Louvrier A, Meyer C, Snäll J, Hagström J, Dovšak T, Birk A, Rocchetti V
Oral Maxillofac Surg 2023 Sep;27(3):479-487. Epub 2022 Jun 17 doi: 10.1007/s10006-022-01091-w. PMID: 35715707
Kämmerer PW, Schneider D, Schiegnitz E, Schneider S, Walter C, Frerich B, Kunkel M
Clin Oral Investig 2016 Sep;20(7):1827-35. Epub 2015 Nov 27 doi: 10.1007/s00784-015-1673-3. PMID: 26612404

Recent clinical studies

Etiology

Kämmerer PW, Schneider D, Schiegnitz E, Schneider S, Walter C, Frerich B, Kunkel M
Clin Oral Investig 2016 Sep;20(7):1827-35. Epub 2015 Nov 27 doi: 10.1007/s00784-015-1673-3. PMID: 26612404
Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508
Song JS, Stefanik D, Damek-Poprawa M, Alawi F, Akintoye SO
Differentiation 2009 Jan;77(1):29-37. Epub 2008 Oct 25 doi: 10.1016/j.diff.2008.09.005. PMID: 19281762Free PMC Article
Hisatomi M, Asaumi JI, Konouchi H, Honda Y, Wakasa T, Kishi K
Oral Dis 2002 Mar;8(2):100-5. doi: 10.1034/j.1601-0825.2002.1c778.x. PMID: 11991304
Kerebel B, Kerebel LM
Oral Surg Oral Med Oral Pathol 1985 Apr;59(4):371-8. doi: 10.1016/0030-4220(85)90062-3. PMID: 2582336

Diagnosis

Ide F, Sakamoto S, Miyazaki Y, Nishimura M, Muramatsu T, Kikuchi K
Head Neck Pathol 2023 Dec;17(4):976-983. Epub 2023 Oct 19 doi: 10.1007/s12105-023-01593-3. PMID: 37856052Free PMC Article
Ćabov T, Fuchs PN, Zulijani A, Ćabov Ercegović L, Marelić S
Acta Clin Croat 2021 Mar;60(1):146-152. doi: 10.20471/acc.2021.60.01.22. PMID: 34588736Free PMC Article
Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508
Sun L, Sun Z, Ma X
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jul;120(1):e11-6. Epub 2015 Apr 4 doi: 10.1016/j.oooo.2015.02.488. PMID: 25921711
Preetha A, Balikai BS, Sujatha D, Pai A, Ganapathy KS
Gen Dent 2010 May-Jun;58(3):e100-2. PMID: 20478785

Therapy

Bertolai R, Acocella A, Sacco R, Agostini T
Minerva Stomatol 2007 Nov-Dec;56(11-12):639-47. PMID: 18091716

Prognosis

Maltagliati A, Ugolini A, Crippa R, Farronato M, Paglia M, Blasi S, Angiero F
Eur J Paediatr Dent 2020 Sep;21(3):199-202. doi: 10.23804/ejpd.2020.21.03.08. PMID: 32893652
Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508
Hidalgo-Sánchez O, Leco-Berrocal MI, Martínez-González JM
Med Oral Patol Oral Cir Bucal 2008 Nov 1;13(11):E730-4. PMID: 18978716
Litonjua LA, Suresh L, Valderrama LS, Neiders ME
Gen Dent 2004 May-Jun;52(3):248-51. PMID: 15206258
Hisatomi M, Asaumi JI, Konouchi H, Honda Y, Wakasa T, Kishi K
Oral Dis 2002 Mar;8(2):100-5. doi: 10.1034/j.1601-0825.2002.1c778.x. PMID: 11991304

Clinical prediction guides

Bomfim BB, Prado R, Sampaio RK, Conde DC, de Andrade BAB, Agostini M, Romañach MJ
Head Neck Pathol 2019 Jun;13(2):125-130. Epub 2018 Mar 19 doi: 10.1007/s12105-018-0913-7. PMID: 29556916Free PMC Article
Liu A, Wu M, Guo X, Guo H, Zhou Z, Wei K, Xuan K
Medicine (Baltimore) 2017 Feb;96(5):e6014. doi: 10.1097/MD.0000000000006014. PMID: 28151902Free PMC Article
Alsufyani NA, Lam EW
Dentomaxillofac Radiol 2011 Mar;40(3):141-6. doi: 10.1259/dmfr/58488265. PMID: 21346079Free PMC Article
Dhanuthai K, Kongin K
J Clin Pediatr Dent 2004 Fall;29(1):75-7. doi: 10.17796/jcpd.29.1.f0543117u42n4476. PMID: 15554408
Takeda Y, Suzuki A, Kuroda M, Yamazaki Y
Int J Oral Maxillofac Surg 1987 Apr;16(2):222-6. doi: 10.1016/s0901-5027(87)80135-2. PMID: 3110324

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