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Complex Odontoma

MedGen UID:: 83166
•Concept ID:: C0334563
•: Neoplastic Process

Synonyms:	Complex odontoma; Complex odontome
SNOMED CT:	Complex odontoma (29020002); Complex odontome (29020002)

Definition

A benign, slow growing, and painless hamartomatous tumor occurring in tooth-bearing areas of the jaws. It is one of the most common odontogenic tumors and it usually affects children, adolescents, and young adults. It is characterized by the presence of enamel and dentin and the absence of tooth-like structures. It is treated with local excision. If it is incompletely removed, it may recur. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVComplex Odontoma

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Hamartoma
        Odontoma
        Complex Odontoma

Professional guidelines

PubMed

The epidemiology and management of odontomas: a European multicenter study.

Boffano P, Cavarra F, Brucoli M, Ruslin M, Forouzanfar T, Ridwan-Pramana A, Rodríguez-Santamarta T, de Vicente JC, Starch-Jensen T, Pechalova P, Pavlov N, Doykova I, Konstantinovic VS, Jezdić Z, Barrabé A, Louvrier A, Meyer C, Snäll J, Hagström J, Dovšak T, Birk A, Rocchetti V
Oral Maxillofac Surg 2023 Sep;27(3):479-487. Epub 2022 Jun 17 doi: 10.1007/s10006-022-01091-w. PMID: 35715707

Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review.

Kämmerer PW, Schneider D, Schiegnitz E, Schneider S, Walter C, Frerich B, Kunkel M
Clin Oral Investig 2016 Sep;20(7):1827-35. Epub 2015 Nov 27 doi: 10.1007/s00784-015-1673-3. PMID: 26612404

See all (2)

Recent clinical studies

Etiology

Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review.

Kämmerer PW, Schneider D, Schiegnitz E, Schneider S, Walter C, Frerich B, Kunkel M
Clin Oral Investig 2016 Sep;20(7):1827-35. Epub 2015 Nov 27 doi: 10.1007/s00784-015-1673-3. PMID: 26612404

Primordial Odontogenic Tumor: Report of a Case.

Slater LJ, Eftimie LF, Herford AS
J Oral Maxillofac Surg 2016 Mar;74(3):547-51. Epub 2015 Sep 18 doi: 10.1016/j.joms.2015.08.019. PMID: 26408843

Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma.

Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508

Differentiation and regenerative capacities of human odontoma-derived mesenchymal cells.

Song JS, Stefanik D, Damek-Poprawa M, Alawi F, Akintoye SO
Differentiation 2009 Jan;77(1):29-37. Epub 2008 Oct 25 doi: 10.1016/j.diff.2008.09.005. PMID: 19281762 Free PMC Article

Erupted complex odontoma: a case report and literature review.

Litonjua LA, Suresh L, Valderrama LS, Neiders ME
Gen Dent 2004 May-Jun;52(3):248-51. PMID: 15206258

See all (21)

Diagnosis

Revisiting the History of Odontoma, with Special Reference to Its Original Illustration.

Ide F, Sakamoto S, Miyazaki Y, Nishimura M, Muramatsu T, Kikuchi K
Head Neck Pathol 2023 Dec;17(4):976-983. Epub 2023 Oct 19 doi: 10.1007/s12105-023-01593-3. PMID: 37856052 Free PMC Article

ODONTOMAS: PEDIATRIC CASE REPORT AND REVIEW OF THE LITERATURE.

Ćabov T, Fuchs PN, Zulijani A, Ćabov Ercegović L, Marelić S
Acta Clin Croat 2021 Mar;60(1):146-152. doi: 10.20471/acc.2021.60.01.22. PMID: 34588736 Free PMC Article

Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma.

Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508

Multiple complex odontoma of the maxilla and the mandible.

Sun L, Sun Z, Ma X
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jul;120(1):e11-6. Epub 2015 Apr 4 doi: 10.1016/j.oooo.2015.02.488. PMID: 25921711

Complex odontoma.

Preetha A, Balikai BS, Sujatha D, Pai A, Ganapathy KS
Gen Dent 2010 May-Jun;58(3):e100-2. PMID: 20478785

See all (54)

Therapy

Submandibular cellulitis (Ludwig's angina) associated to a complex odontoma erupted into the oral cavity. Case report and literature review.

Bertolai R, Acocella A, Sacco R, Agostini T
Minerva Stomatol 2007 Nov-Dec;56(11-12):639-47. PMID: 18091716

See all (1)

Prognosis

Complex odontoma at the upper right maxilla: Surgical management and histomorphological profile.

Maltagliati A, Ugolini A, Crippa R, Farronato M, Paglia M, Blasi S, Angiero F
Eur J Paediatr Dent 2020 Sep;21(3):199-202. doi: 10.23804/ejpd.2020.21.03.08. PMID: 32893652

Primordial Odontogenic Tumor: Report of a Case.

Slater LJ, Eftimie LF, Herford AS
J Oral Maxillofac Surg 2016 Mar;74(3):547-51. Epub 2015 Sep 18 doi: 10.1016/j.joms.2015.08.019. PMID: 26408843

Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma.

Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M
Niger J Clin Pract 2015 Nov-Dec;18(6):726-30. doi: 10.4103/1119-3077.154209. PMID: 26289508

Metaanalysis of the epidemiology and clinical manifestations of odontomas.

Hidalgo-Sánchez O, Leco-Berrocal MI, Martínez-González JM
Med Oral Patol Oral Cir Bucal 2008 Nov 1;13(11):E730-4. PMID: 18978716

Erupted complex odontoma: a case report and literature review.

Litonjua LA, Suresh L, Valderrama LS, Neiders ME
Gen Dent 2004 May-Jun;52(3):248-51. PMID: 15206258

See all (15)

Clinical prediction guides

Primordial Odontogenic Tumor: Report of a New Case and Literature Review.

Bomfim BB, Prado R, Sampaio RK, Conde DC, de Andrade BAB, Agostini M, Romañach MJ
Head Neck Pathol 2019 Jun;13(2):125-130. Epub 2018 Mar 19 doi: 10.1007/s12105-018-0913-7. PMID: 29556916 Free PMC Article

Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report.

Liu A, Wu M, Guo X, Guo H, Zhou Z, Wei K, Xuan K
Medicine (Baltimore) 2017 Feb;96(5):e6014. doi: 10.1097/MD.0000000000006014. PMID: 28151902 Free PMC Article

Cemento-osseous dysplasia of the jaw bones: key radiographic features.

Alsufyani NA, Lam EW
Dentomaxillofac Radiol 2011 Mar;40(3):141-6. doi: 10.1259/dmfr/58488265. PMID: 21346079 Free PMC Article

Ameloblastic fibro-odontoma: a case report.

Dhanuthai K, Kongin K
J Clin Pediatr Dent 2004 Fall;29(1):75-7. doi: 10.17796/jcpd.29.1.f0543117u42n4476. PMID: 15554408

Melanin-pigment in complex odontoma.

Takeda Y, Suzuki A, Kuroda M, Yamazaki Y
Int J Oral Maxillofac Surg 1987 Apr;16(2):222-6. doi: 10.1016/s0901-5027(87)80135-2. PMID: 3110324

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