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Cutaneous mastocytoma

MedGen UID:
83357
•Concept ID:
C0343115
•
Neoplastic Process
Synonyms: Mastocytoma, Skin; Skin Mastocytoma; Solitary Mastocytoma of Skin
SNOMED CT: Solitary cutaneous mastocytoma (397013007); Cutaneous mastocytoma (397013007); Solitary mastocytoma (397013007); Solitary mastocytoma of skin (703836007); Mastocytoma of skin (239147000); Mast cell nevus (239147000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0019314
Orphanet: ORPHA79455

Definition

Cutaneous mastocytoma is a form of cutaneous mastocytosis (CM, see this term) generally characterized by the presence of a solitary or multiple hyperpigmented macules, plaques or nodules associated with abnormal accumulation of mast cells in the skin. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous mastocytoma
Follow this link to review classifications for Cutaneous mastocytoma in Orphanet.

Professional guidelines

PubMed

Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511Free PMC Article

Recent clinical studies

Etiology

Solitary mastocytoma of the eyelid.
Naysan J, Kodsi SR, Kristal L
J AAPOS 2013 Aug;17(4):443-4. Epub 2013 Jul 17 doi: 10.1016/j.jaapos.2013.04.002. PMID: 23871296
Immunoreactivity of human tissue mast cells: nonspecific binding of primary antibodies against regulatory peptides by ionic linkage.
Ruck P, Horny HP, Kaiserling E
J Histochem Cytochem 1990 Jun;38(6):859-67. doi: 10.1177/38.6.2335741. PMID: 2335741
Cutaneous mastocytosis in children: anaesthetic considerations.
James PD, Krafchik BR, Johnston AE
Can J Anaesth 1987 Sep;34(5):522-4. doi: 10.1007/BF03014363. PMID: 3664922

Diagnosis

Rare presentation of adult-onset cutaneous mastocytoma of the breast.
Kim J, Malakouti M, Luke J, Kerstetter J
Dermatol Online J 2020 Nov 15;26(11) PMID: 33342184
Systemic mastocytosis associated with Hodgkin's lymphoma in a 4-year-old child.
Srinivas SM, Agarwal R, Babu N, Naik M, Kumar R, Dhar S
Pediatr Dermatol 2020 Jul;37(4):713-715. Epub 2020 Apr 22 doi: 10.1111/pde.14183. PMID: 32319109
Solitary mastocytoma of the eyelid.
Naysan J, Kodsi SR, Kristal L
J AAPOS 2013 Aug;17(4):443-4. Epub 2013 Jul 17 doi: 10.1016/j.jaapos.2013.04.002. PMID: 23871296
Flushing due to solitary cutaneous mastocytoma can be prevented by hydrocolloid dressings.
Yung A
Pediatr Dermatol 2004 May-Jun;21(3):262-4. doi: 10.1111/j.0736-8046.2004.21316.x. PMID: 15165209
Solitary mastocytoma in an infant - case report with review of literature.
Kacker A, Huo J, Huang R, Hoda RS
Int J Pediatr Otorhinolaryngol 2000 Jan 30;52(1):93-5. doi: 10.1016/s0165-5876(99)00291-8. PMID: 10699246

Therapy

Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511Free PMC Article
Cutaneous mastocytosis in children: anaesthetic considerations.
James PD, Krafchik BR, Johnston AE
Can J Anaesth 1987 Sep;34(5):522-4. doi: 10.1007/BF03014363. PMID: 3664922

Clinical prediction guides

Infrequent associations of cutis marmorata telangiectatica congenita: a two-case report.
Moreno-Alfonso JC, Molina Caballero A, Pérez Martínez A
Cir Pediatr 2024 Jan 1;37(1):33-36. doi: 10.54847/cp.2024.01.15. PMID: 38180100
Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511Free PMC Article

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