Cutaneous mastocytoma

MedGen UID:: 83357
•Concept ID:: C0343115
•: Neoplastic Process

Synonyms:	Mastocytoma, Skin; Skin Mastocytoma; Solitary Mastocytoma of Skin
SNOMED CT:	Solitary cutaneous mastocytoma (397013007); Cutaneous mastocytoma (397013007); Solitary mastocytoma (397013007); Solitary mastocytoma of skin (703836007); Mastocytoma of skin (239147000); Mast cell nevus (239147000)
Modes of inheritance:	Not genetically inherited MedGen UID: 988794 •Concept ID: CN307044 • Finding Source: Orphanet clinical entity without genetic inheritance. See: This record Not genetically inherited (Orphanet)

Monarch Initiative:	MONDO:0019314
Orphanet:	ORPHA79455

Definition

Cutaneous mastocytoma is a form of cutaneous mastocytosis (CM, see this term) generally characterized by the presence of a solitary or multiple hyperpigmented macules, plaques or nodules associated with abnormal accumulation of mast cells in the skin. [from ORDO]

Term Hierarchy

GTR
MeSH
Orphanet

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCutaneous mastocytoma

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Benign neoplasm
        Benign mastocytoma
        Cutaneous mastocytoma

Follow this link to review classifications for Cutaneous mastocytoma in Orphanet.

Professional guidelines

PubMed

Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.

Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511 Free PMC Article

See all (1)

Recent clinical studies

Etiology

Solitary mastocytoma of the eyelid.

Naysan J, Kodsi SR, Kristal L
J AAPOS 2013 Aug;17(4):443-4. Epub 2013 Jul 17 doi: 10.1016/j.jaapos.2013.04.002. PMID: 23871296

Immunoreactivity of human tissue mast cells: nonspecific binding of primary antibodies against regulatory peptides by ionic linkage.

Ruck P, Horny HP, Kaiserling E
J Histochem Cytochem 1990 Jun;38(6):859-67. doi: 10.1177/38.6.2335741. PMID: 2335741

Cutaneous mastocytosis in children: anaesthetic considerations.

James PD, Krafchik BR, Johnston AE
Can J Anaesth 1987 Sep;34(5):522-4. doi: 10.1007/BF03014363. PMID: 3664922

See all (3)

Diagnosis

Case report of a clinically indolent but morphologically high-grade cutaneous mast cell tumor in an adult: Atypical cutaneous mastocytoma or mast cell sarcoma?

Wardle CLW, Oldhoff JM, Diepstra A, Valent P, Horny HP, Oude Elberink HNG, Kluin PM, Diercks GFH
J Cutan Pathol 2021 Nov;48(11):1404-1409. Epub 2021 Jul 2 doi: 10.1111/cup.14088. PMID: 34152029 Free PMC Article

Rare presentation of adult-onset cutaneous mastocytoma of the breast.

Kim J, Malakouti M, Luke J, Kerstetter J
Dermatol Online J 2020 Nov 15;26(11) PMID: 33342184

Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.

Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511 Free PMC Article

Pleomorphic mastocytoma in an adult.

Exposito-Serrano V, Agut-Busquet E, Leal Canosa L, Herrerías Moreno J, Saez A, Luelmo J
J Cutan Pathol 2018 Feb;45(2):176-179. Epub 2017 Dec 11 doi: 10.1111/cup.13080. PMID: 29148588

Solitary mastocytoma of the eyelid.

Naysan J, Kodsi SR, Kristal L
J AAPOS 2013 Aug;17(4):443-4. Epub 2013 Jul 17 doi: 10.1016/j.jaapos.2013.04.002. PMID: 23871296

See all (11)