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Adult Nasal Type Extranodal NK/T-Cell Lymphoma

MedGen UID:
853495
•Concept ID:
C1879279
•
Neoplastic Process

Definition

Nasal type extranodal NK/T-cell lymphoma that occurs in adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Nasal Type Extranodal NK/T-Cell Lymphoma

Professional guidelines

PubMed

Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group.
Qi SN, Li YX, Specht L, Oguchi M, Tsang R, Ng A, Suh CO, Ricardi U, Mac Manus M, Dabaja B, Yahalom J
Int J Radiat Oncol Biol Phys 2021 Jul 15;110(4):1064-1081. Epub 2021 Feb 11 doi: 10.1016/j.ijrobp.2021.02.011. PMID: 33581262
Diagnosis and management of natural killer-cell malignancies.
Ishida F, Kwong YL
Expert Rev Hematol 2010 Oct;3(5):593-602. doi: 10.1586/ehm.10.51. PMID: 21083476
Treatment of T-cell non-Hodgkin's lymphoma.
Evens AM, Gartenhaus RB
Curr Treat Options Oncol 2004 Aug;5(4):289-303. doi: 10.1007/s11864-004-0020-8. PMID: 15233906

Recent clinical studies

Etiology

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group.
Qi SN, Li YX, Specht L, Oguchi M, Tsang R, Ng A, Suh CO, Ricardi U, Mac Manus M, Dabaja B, Yahalom J
Int J Radiat Oncol Biol Phys 2021 Jul 15;110(4):1064-1081. Epub 2021 Feb 11 doi: 10.1016/j.ijrobp.2021.02.011. PMID: 33581262
Mature T- and NK-cell non-Hodgkin lymphoma in children and young adolescents.
Pillai V, Tallarico M, Bishop MR, Lim MS
Br J Haematol 2016 May;173(4):573-81. Epub 2016 Mar 15 doi: 10.1111/bjh.14044. PMID: 26992145
Nasopharyngeal/nasal type NK/T lymphoma: analysis of 23 cases and current review of the literature.
Youssef YB, Bougmiza I, Bouabid Z, Achour B, Regaieg H, Sriha B, Belkadhi M, Omri HE, Khelif A
Kulak Burun Bogaz Ihtis Derg 2012 Sep-Oct;22(5):275-83. doi: 10.5606/kbbihtisas.2012.053. PMID: 22991988
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

Diagnosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Extranodal NK/T-cell lymphoma, nasal type: Clinical features, outcome, and prognostic factors in 101 cases.
Su YJ, Wang PN, Chang H, Shih LY, Lin TL, Kuo MC, Chuang WY, Wu JH, Tang TC, Hung YS, Dunn P, Kao HW
Eur J Haematol 2018 Sep;101(3):379-388. Epub 2018 Jul 27 doi: 10.1111/ejh.13126. PMID: 29908084
Natural killer/T-cell lymphomas in pediatric and adolescent patients.
Termuhlen AM
Clin Adv Hematol Oncol 2017 Mar;15(3):200-209. PMID: 28398275
Mature T- and NK-cell non-Hodgkin lymphoma in children and young adolescents.
Pillai V, Tallarico M, Bishop MR, Lim MS
Br J Haematol 2016 May;173(4):573-81. Epub 2016 Mar 15 doi: 10.1111/bjh.14044. PMID: 26992145
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

Therapy

Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Improved prognosis of extranodal NK/T cell lymphoma, nasal type of nasal origin but not extranasal origin.
Yamaguchi M, Suzuki R, Miyazaki K, Amaki J, Takizawa J, Sekiguchi N, Kinoshita S, Tomita N, Wada H, Kobayashi Y, Niitsu N, Ando T, Maeda T, Saito B, Matsuoka H, Sakai R, Kubota N, Masaki Y, Kameoka Y, Asano N, Oguchi M, Katayama N
Ann Hematol 2019 Jul;98(7):1647-1655. Epub 2019 Apr 19 doi: 10.1007/s00277-019-03689-9. PMID: 31001658
Extranodal NK/T-cell lymphoma, nasal type: Clinical features, outcome, and prognostic factors in 101 cases.
Su YJ, Wang PN, Chang H, Shih LY, Lin TL, Kuo MC, Chuang WY, Wu JH, Tang TC, Hung YS, Dunn P, Kao HW
Eur J Haematol 2018 Sep;101(3):379-388. Epub 2018 Jul 27 doi: 10.1111/ejh.13126. PMID: 29908084
Mature T- and NK-cell non-Hodgkin lymphoma in children and young adolescents.
Pillai V, Tallarico M, Bishop MR, Lim MS
Br J Haematol 2016 May;173(4):573-81. Epub 2016 Mar 15 doi: 10.1111/bjh.14044. PMID: 26992145
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

Prognosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group.
Qi SN, Li YX, Specht L, Oguchi M, Tsang R, Ng A, Suh CO, Ricardi U, Mac Manus M, Dabaja B, Yahalom J
Int J Radiat Oncol Biol Phys 2021 Jul 15;110(4):1064-1081. Epub 2021 Feb 11 doi: 10.1016/j.ijrobp.2021.02.011. PMID: 33581262
Extranodal NK/T-cell lymphoma, nasal type: Clinical features, outcome, and prognostic factors in 101 cases.
Su YJ, Wang PN, Chang H, Shih LY, Lin TL, Kuo MC, Chuang WY, Wu JH, Tang TC, Hung YS, Dunn P, Kao HW
Eur J Haematol 2018 Sep;101(3):379-388. Epub 2018 Jul 27 doi: 10.1111/ejh.13126. PMID: 29908084
EBV in T-/NK-Cell Tumorigenesis.
Kimura H
Adv Exp Med Biol 2018;1045:459-475. doi: 10.1007/978-981-10-7230-7_21. PMID: 29896680
Natural killer/T-cell lymphomas in pediatric and adolescent patients.
Termuhlen AM
Clin Adv Hematol Oncol 2017 Mar;15(3):200-209. PMID: 28398275

Clinical prediction guides

Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Mutational profile and EBV strains of extranodal NK/T-cell lymphoma, nasal type in Latin America.
Montes-Mojarro IA, Chen BJ, Ramirez-Ibarguen AF, Quezada-Fiallos CM, Pérez-Báez WB, Dueñas D, Casavilca-Zambrano S, Ortiz-Mayor M, Rojas-Bilbao E, García-Rivello H, Metrebian MF, Narbaitz M, Barrionuevo C, Lome-Maldonado C, Bonzheim I, Fend F, Steinhilber J, Quintanilla-Martinez L
Mod Pathol 2020 May;33(5):781-791. Epub 2019 Dec 10 doi: 10.1038/s41379-019-0415-5. PMID: 31822801
Extranodal natural killer/T-cell lymphoma, nasal type: a Spanish multicentric retrospective survey.
Rozas-Muñoz E, Gallardo F, Pujol RM, Pérez-Ferriols A, Servitje O, Estrach T, Bastida J, Román C, Palacio-Aller L, Gil I, Martí RM, Vidal-Sarró D, García-Muret MP
Eur J Dermatol 2018 Feb 1;28(1):64-70. doi: 10.1684/ejd.2017.3205. PMID: 29400283
Nasopharyngeal/nasal type NK/T lymphoma: analysis of 23 cases and current review of the literature.
Youssef YB, Bougmiza I, Bouabid Z, Achour B, Regaieg H, Sriha B, Belkadhi M, Omri HE, Khelif A
Kulak Burun Bogaz Ihtis Derg 2012 Sep-Oct;22(5):275-83. doi: 10.5606/kbbihtisas.2012.053. PMID: 22991988
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

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