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Post-treatment Lyme disease syndrome

MedGen UID:
855646
Concept ID:
C3890422
Disease or Syndrome
Synonyms: Lyme Disease, Post-Treatment; Post Treatment Lyme Disease; Post Treatment Lyme Disease Syndrome; Post-Treatment Lyme Disease; Post-Treatment Lyme Disease Syndrome
 
Monarch Initiative: MONDO:0700280

Definition

A constellation of symptoms lasting months to years reported by some Lyme disease patients who had undergone previous antibiotic therapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPost-treatment Lyme disease syndrome

Professional guidelines

PubMed

Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article
Wong KH, Shapiro ED, Soffer GK
Clin Rev Allergy Immunol 2022 Feb;62(1):264-271. Epub 2021 Oct 23 doi: 10.1007/s12016-021-08906-w. PMID: 34687445
Kullberg BJ, Vrijmoeth HD, van de Schoor F, Hovius JW
BMJ 2020 May 26;369:m1041. doi: 10.1136/bmj.m1041. PMID: 32457042

Recent clinical studies

Etiology

Dersch R, Torbahn G, Rauer S
Eur J Neurol 2024 Jul;31(7):e16293. Epub 2024 Apr 12 doi: 10.1111/ene.16293. PMID: 38606630Free PMC Article
Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article
Kullberg BJ, Vrijmoeth HD, van de Schoor F, Hovius JW
BMJ 2020 May 26;369:m1041. doi: 10.1136/bmj.m1041. PMID: 32457042
Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, Welsh O
Eur J Clin Microbiol Infect Dis 2019 Feb;38(2):201-208. Epub 2018 Nov 19 doi: 10.1007/s10096-018-3417-1. PMID: 30456435
Koedel U, Fingerle V, Pfister HW
Nat Rev Neurol 2015 Aug;11(8):446-56. Epub 2015 Jul 28 doi: 10.1038/nrneurol.2015.121. PMID: 26215621

Diagnosis

Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article
Wong KH, Shapiro ED, Soffer GK
Clin Rev Allergy Immunol 2022 Feb;62(1):264-271. Epub 2021 Oct 23 doi: 10.1007/s12016-021-08906-w. PMID: 34687445
Kullberg BJ, Vrijmoeth HD, van de Schoor F, Hovius JW
BMJ 2020 May 26;369:m1041. doi: 10.1136/bmj.m1041. PMID: 32457042
Summer G, Rupprecht TA
Rev Neurol (Paris) 2019 Sep-Oct;175(7-8):417-419. Epub 2019 Jul 31 doi: 10.1016/j.neurol.2019.07.012. PMID: 31376993
Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, Welsh O
Eur J Clin Microbiol Infect Dis 2019 Feb;38(2):201-208. Epub 2018 Nov 19 doi: 10.1007/s10096-018-3417-1. PMID: 30456435

Therapy

Dersch R, Torbahn G, Rauer S
Eur J Neurol 2024 Jul;31(7):e16293. Epub 2024 Apr 12 doi: 10.1111/ene.16293. PMID: 38606630Free PMC Article
Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article
Kullberg BJ, Vrijmoeth HD, van de Schoor F, Hovius JW
BMJ 2020 May 26;369:m1041. doi: 10.1136/bmj.m1041. PMID: 32457042
Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, Welsh O
Eur J Clin Microbiol Infect Dis 2019 Feb;38(2):201-208. Epub 2018 Nov 19 doi: 10.1007/s10096-018-3417-1. PMID: 30456435
Koedel U, Fingerle V, Pfister HW
Nat Rev Neurol 2015 Aug;11(8):446-56. Epub 2015 Jul 28 doi: 10.1038/nrneurol.2015.121. PMID: 26215621

Prognosis

Musonera JB, Valiquette L, Baron G, Milord F, Marcoux D, Thivierge K, Bedard-Dallaire S, Pelletier AA, Lachance R, Bourget J, Simard C, Cantin E, Abbasi F, Haraoui LP, Carignan A
CMAJ Open 2022 Apr-Jun;10(2):E570-E576. Epub 2022 Jun 28 doi: 10.9778/cmajo.20210063. PMID: 35764331Free PMC Article
Gynthersen RMM, Tetens MM, Ørbæk M, Haahr R, Fana V, Hansen K, Mens H, Andersen ÅB, Lebech AM
Ticks Tick Borne Dis 2021 Jan;12(1):101591. Epub 2020 Oct 9 doi: 10.1016/j.ttbdis.2020.101591. PMID: 33126203
Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, Welsh O
Eur J Clin Microbiol Infect Dis 2019 Feb;38(2):201-208. Epub 2018 Nov 19 doi: 10.1007/s10096-018-3417-1. PMID: 30456435
Moon KA, Pollak J, Hirsch AG, Aucott JN, Nordberg C, Heaney CD, Schwartz BS
Ticks Tick Borne Dis 2019 Feb;10(2):241-250. Epub 2018 Oct 26 doi: 10.1016/j.ttbdis.2018.10.010. PMID: 30420251
Nemeth J, Bernasconi E, Heininger U, Abbas M, Nadal D, Strahm C, Erb S, Zimmerli S, Furrer H, Delaloye J, Kuntzer T, Altpeter E, Sturzenegger M, Weber R, For The Swiss Society For Infectious Diseases And The Swiss Society For Neurology
Swiss Med Wkly 2016;146:w14353. Epub 2016 Dec 5 doi: 10.4414/smw.2016.14353. PMID: 27922168

Clinical prediction guides

Dersch R, Torbahn G, Rauer S
Eur J Neurol 2024 Jul;31(7):e16293. Epub 2024 Apr 12 doi: 10.1111/ene.16293. PMID: 38606630Free PMC Article
Novak P, Systrom DM, Marciano SP, Knief A, Felsenstein D, Giannetti MP, Hamilton MJ, Nicoloro-SantaBarbara J, Saco TV, Castells M, Farhad K, Pilgrim DM, Mullally WJ
Sci Rep 2024 Jan 30;14(1):2513. doi: 10.1038/s41598-024-52368-x. PMID: 38291116Free PMC Article
Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article
Gorlyn M, Keilp JG, Fallon BA
Arch Clin Neuropsychol 2023 May 22;38(4):650-654. doi: 10.1093/arclin/acac095. PMID: 36548120Free PMC Article
Keilp JG, Corbera K, Gorlyn M, Oquendo MA, Mann JJ, Fallon BA
Arch Clin Neuropsychol 2019 Jun 1;34(4):466-480. doi: 10.1093/arclin/acy083. PMID: 30418507

Recent systematic reviews

Dersch R, Torbahn G, Rauer S
Eur J Neurol 2024 Jul;31(7):e16293. Epub 2024 Apr 12 doi: 10.1111/ene.16293. PMID: 38606630Free PMC Article
Sébastien P, Jacques D, Catherine P, Xavier G
BMC Infect Dis 2023 Oct 2;23(1):642. doi: 10.1186/s12879-023-08618-w. PMID: 37784031Free PMC Article

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