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Phrenic Nerve Palsy Related to Birth

MedGen UID:
857522
•Concept ID:
C3897928
•
Disease or Syndrome

Definition

A condition characterized by reduced or absent movement of the ipsilateral diaphragm as a consequence of an injury to the phrenic nerve or its origin in cervical roots 3 through 5 sustained during the birthing process. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhrenic Nerve Palsy Related to Birth

Recent clinical studies

Etiology

Retropharyngeal Contralateral C7 Nerve Transfer to the Lower Trunk for Brachial Plexus Birth Injury: Technique and Results.
Vu AT, Sparkman DM, van Belle CJ, Yakuboff KP, Schwentker AR
J Hand Surg Am 2018 May;43(5):417-424. Epub 2018 Feb 3 doi: 10.1016/j.jhsa.2017.12.001. PMID: 29395588
Surgical closure of patent ductus arteriosus in preterm low birth weight infants.
Mandhan P, Brown S, Kukkady A, Samarakkody U
Congenit Heart Dis 2009 Jan-Feb;4(1):34-7. doi: 10.1111/j.1747-0803.2008.00241.x. PMID: 19207401

Diagnosis

Hemidiaphragmatic paralysis in preterm neonates: a rare complication of peripherally inserted central catheter extravasation.
Tosello B, Michel F, Merrot T, Chaumoître K, Hassid S, Lagier P, Martin C
J Pediatr Surg 2011 Jul;46(7):E17-21. doi: 10.1016/j.jpedsurg.2011.03.065. PMID: 21763820
Surgical closure of patent ductus arteriosus in preterm low birth weight infants.
Mandhan P, Brown S, Kukkady A, Samarakkody U
Congenit Heart Dis 2009 Jan-Feb;4(1):34-7. doi: 10.1111/j.1747-0803.2008.00241.x. PMID: 19207401
Diaphragmatic paralysis in children: a review of 11 cases.
Commare MC, Kurstjens SP, Barois A
Pediatr Pulmonol 1994 Sep;18(3):187-93. doi: 10.1002/ppul.1950180311. PMID: 7800436

Therapy

Hemidiaphragmatic paralysis in preterm neonates: a rare complication of peripherally inserted central catheter extravasation.
Tosello B, Michel F, Merrot T, Chaumoître K, Hassid S, Lagier P, Martin C
J Pediatr Surg 2011 Jul;46(7):E17-21. doi: 10.1016/j.jpedsurg.2011.03.065. PMID: 21763820

Prognosis

Retropharyngeal Contralateral C7 Nerve Transfer to the Lower Trunk for Brachial Plexus Birth Injury: Technique and Results.
Vu AT, Sparkman DM, van Belle CJ, Yakuboff KP, Schwentker AR
J Hand Surg Am 2018 May;43(5):417-424. Epub 2018 Feb 3 doi: 10.1016/j.jhsa.2017.12.001. PMID: 29395588
Surgical closure of patent ductus arteriosus in preterm low birth weight infants.
Mandhan P, Brown S, Kukkady A, Samarakkody U
Congenit Heart Dis 2009 Jan-Feb;4(1):34-7. doi: 10.1111/j.1747-0803.2008.00241.x. PMID: 19207401
An overlooked association of brachial plexus palsy: diaphragmatic paralysis.
Karabiber H, Ozkan KU, Garipardic M, Parmaksiz G
Acta Paediatr Taiwan 2004 Sep-Oct;45(5):301-3. PMID: 15868816

Clinical prediction guides

Surgical closure of patent ductus arteriosus in preterm low birth weight infants.
Mandhan P, Brown S, Kukkady A, Samarakkody U
Congenit Heart Dis 2009 Jan-Feb;4(1):34-7. doi: 10.1111/j.1747-0803.2008.00241.x. PMID: 19207401
Obstetric antecedents of surgically treated obstetric brachial plexus injuries.
Ubachs JM, Slooff AC, Peeters LL
Br J Obstet Gynaecol 1995 Oct;102(10):813-7. doi: 10.1111/j.1471-0528.1995.tb10848.x. PMID: 7547739

Recent systematic reviews

Donor complications of contralateral C7 nerve transfer in Brachial Plexus Birth Injury: a systematic review.
Jakeman M, Borschel GH, Sharma P
Childs Nerv Syst 2023 Dec;39(12):3515-3520. Epub 2023 Jun 27 doi: 10.1007/s00381-023-06047-3. PMID: 37368067

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