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Invasive Bladder Urothelial Carcinoma Associated with Urethral Carcinoma

MedGen UID:
858358
•Concept ID:
C3898764
•
Neoplastic Process
Synonym: Infiltrating Bladder Urothelial Carcinoma Associated with Urethral Carcinoma

Definition

Invasive urothelial carcinoma of the bladder which is associated with the presence of in situ or infiltrating urethral carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Bladder Urothelial Carcinoma Associated with Urethral Carcinoma

Professional guidelines

PubMed

Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
T1G3 high-risk NMIBC (non-muscle invasive bladder cancer): conservative treatment versus immediate cystectomy.
De Berardinis E, Busetto GM, Antonini G, Giovannone R, Gentile V
Int Urol Nephrol 2011 Dec;43(4):1047-57. Epub 2011 Mar 29 doi: 10.1007/s11255-011-9941-x. PMID: 21442469
Bladder cancer: current management and opportunities for a personalized approach.
Galsky MD, Hall SJ
Mt Sinai J Med 2010 Nov-Dec;77(6):587-96. doi: 10.1002/msj.20224. PMID: 21105122

Recent clinical studies

Etiology

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Urethral recurrence after radical cystectomy for urothelial carcinoma: A systematic review and meta-analysis.
Fahmy O, Khairul-Asri MG, Schubert T, Renninger M, Kübler H, Stenzl A, Gakis G
Urol Oncol 2018 Feb;36(2):54-59. Epub 2017 Nov 28 doi: 10.1016/j.urolonc.2017.11.007. PMID: 29196179
Improving diagnostic molecular tests to monitor urothelial carcinoma recurrence.
Krabbe LM, Woldu SL, Shariat SF, Lotan Y
Expert Rev Mol Diagn 2016 Nov;16(11):1189-1199. Epub 2016 Oct 14 doi: 10.1080/14737159.2016.1244006. PMID: 27696932
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Urothelial carcinoma in the prostatic urethra and prostate: current controversies.
Liedberg F, Chebil G, Månsson W
Expert Rev Anticancer Ther 2007 Mar;7(3):383-90. doi: 10.1586/14737140.7.3.383. PMID: 17338657

Diagnosis

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Novel Noninvasive Diagnostics.
Wiley C, Wise CF, Breen M
Vet Clin North Am Small Anim Pract 2019 Sep;49(5):781-791. Epub 2019 Jul 4 doi: 10.1016/j.cvsm.2019.05.002. PMID: 31280902
Improving diagnostic molecular tests to monitor urothelial carcinoma recurrence.
Krabbe LM, Woldu SL, Shariat SF, Lotan Y
Expert Rev Mol Diagn 2016 Nov;16(11):1189-1199. Epub 2016 Oct 14 doi: 10.1080/14737159.2016.1244006. PMID: 27696932
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Urothelial carcinoma in the prostatic urethra and prostate: current controversies.
Liedberg F, Chebil G, Månsson W
Expert Rev Anticancer Ther 2007 Mar;7(3):383-90. doi: 10.1586/14737140.7.3.383. PMID: 17338657

Therapy

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Palliative intralesional interleukin-2 treatment in dogs with urinary bladder and urethral carcinomas.
Konietschke U, Teske E, Jurina K, Stockhaus C
In Vivo 2012 Nov-Dec;26(6):931-5. PMID: 23160674
Bladder cancer: current management and opportunities for a personalized approach.
Galsky MD, Hall SJ
Mt Sinai J Med 2010 Nov-Dec;77(6):587-96. doi: 10.1002/msj.20224. PMID: 21105122
Urothelial carcinoma in the prostatic urethra and prostate: current controversies.
Liedberg F, Chebil G, Månsson W
Expert Rev Anticancer Ther 2007 Mar;7(3):383-90. doi: 10.1586/14737140.7.3.383. PMID: 17338657

Prognosis

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Condyloma Acuminatum of Urinary Bladder: Relation to Squamous Cell Carcinoma.
Samarska IV, Epstein JI
Am J Surg Pathol 2019 Nov;43(11):1547-1553. doi: 10.1097/PAS.0000000000001339. PMID: 31368913
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Urothelial carcinoma of the bladder in patients on hemodialysis: clinical characteristics and oncological outcomes.
Yossepowitch O, Sagy I, Margel D, Baniel J
J Urol 2012 Apr;187(4):1215-9. Epub 2012 Feb 14 doi: 10.1016/j.juro.2011.11.098. PMID: 22335874
Urothelial carcinoma in the prostatic urethra and prostate: current controversies.
Liedberg F, Chebil G, Månsson W
Expert Rev Anticancer Ther 2007 Mar;7(3):383-90. doi: 10.1586/14737140.7.3.383. PMID: 17338657

Clinical prediction guides

Association Between Perioperative Chemotherapy and Survival in Men Undergoing Radical Resection for Primary Urethral Urothelial Carcinoma: An Analysis of the National Cancer Database.
Celtik K, Lim K, Dursun F, Xu J, Klaassen Z, Zhang J, Efstathiou E, Sonpavde G, Wallis C, Satkunasivam R
Clin Genitourin Cancer 2022 Jun;20(3):244-251. Epub 2022 Jan 31 doi: 10.1016/j.clgc.2022.01.011. PMID: 35181268
Incidental prostate cancer in patients with bladder urothelial carcinoma: comprehensive analysis of 1,476 radical cystoprostatectomy specimens.
Bruins HM, Djaladat H, Ahmadi H, Sherrod A, Cai J, Miranda G, Skinner EC, Daneshmand S
J Urol 2013 Nov;190(5):1704-9. Epub 2013 May 23 doi: 10.1016/j.juro.2013.05.034. PMID: 23707451
Palliative intralesional interleukin-2 treatment in dogs with urinary bladder and urethral carcinomas.
Konietschke U, Teske E, Jurina K, Stockhaus C
In Vivo 2012 Nov-Dec;26(6):931-5. PMID: 23160674
Behavior of urothelial carcinoma with respect to anatomical location.
Catto JW, Yates DR, Rehman I, Azzouzi AR, Patterson J, Sibony M, Cussenot O, Hamdy FC
J Urol 2007 May;177(5):1715-20. doi: 10.1016/j.juro.2007.01.030. PMID: 17437794
Urethral tumor recurrence following cystectomy and urinary diversion: clinical and pathological characteristics in 768 male patients.
Stein JP, Clark P, Miranda G, Cai J, Groshen S, Skinner DG
J Urol 2005 Apr;173(4):1163-8. doi: 10.1097/01.ju.0000149679.56884.0f. PMID: 15758728

Recent systematic reviews

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Urethral recurrence after radical cystectomy for urothelial carcinoma: A systematic review and meta-analysis.
Fahmy O, Khairul-Asri MG, Schubert T, Renninger M, Kübler H, Stenzl A, Gakis G
Urol Oncol 2018 Feb;36(2):54-59. Epub 2017 Nov 28 doi: 10.1016/j.urolonc.2017.11.007. PMID: 29196179

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