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Facial Nerve Palsy Related to Birth

MedGen UID:
858754
•Concept ID:
C3899160
•
Disease or Syndrome

Definition

A condition characterized by reduced or absent movement of the ipsilateral face as a consequence of an injury to the seventh cranial nerve sustained during the birthing process. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFacial Nerve Palsy Related to Birth

Professional guidelines

PubMed

Part 1: early recognition and treatment of birth trauma: injuries to the head and face.
Parker LA
Adv Neonatal Care 2005 Dec;5(6):288-97; quiz 298-300. doi: 10.1016/j.adnc.2005.09.001. PMID: 16338668
Facial paralysis in children: differential diagnosis.
May M, Fria TJ, Blumenthal F, Curtin H
Otolaryngol Head Neck Surg 1981 Sep-Oct;89(5):841-8. doi: 10.1177/019459988108900528. PMID: 6799919
Medical and psychosocial aspects of the habilitation of thalidomide children.
Mongeau M, Gingras G, Sherman ED, Hebert B, Hutchison J, Corriveau C
Can Med Assoc J 1966 Aug 27;95(9):390-5. PMID: 5923651Free PMC Article

Recent clinical studies

Etiology

Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or 'classical' congenital myopathy.
Zaharieva IT, Thor MG, Oates EC, van Karnebeek C, Hendson G, Blom E, Witting N, Rasmussen M, Gabbett MT, Ravenscroft G, Sframeli M, Suetterlin K, Sarkozy A, D'Argenzio L, Hartley L, Matthews E, Pitt M, Vissing J, Ballegaard M, Krarup C, Slørdahl A, Halvorsen H, Ye XC, Zhang LH, Løkken N, Werlauff U, Abdelsayed M, Davis MR, Feng L, Phadke R, Sewry CA, Morgan JE, Laing NG, Vallance H, Ruben P, Hanna MG, Lewis S, Kamsteeg EJ, Männikkö R, Muntoni F
Brain 2016 Mar;139(Pt 3):674-91. Epub 2015 Dec 22 doi: 10.1093/brain/awv352. PMID: 26700687Free PMC Article
Forceps Delivery-Related Ophthalmic Injuries: A Case Series.
McAnena L, O'Keefe M, Kirwan C, Murphy J
J Pediatr Ophthalmol Strabismus 2015 Nov-Dec;52(6):355-9. doi: 10.3928/01913913-20151014-50. PMID: 26584749
Part 1: early recognition and treatment of birth trauma: injuries to the head and face.
Parker LA
Adv Neonatal Care 2005 Dec;5(6):288-97; quiz 298-300. doi: 10.1016/j.adnc.2005.09.001. PMID: 16338668
Autogenous fascia lata grafts: clinical applications in reanimation of the totally or partially paralyzed face.
Rose EH
Plast Reconstr Surg 2005 Jul;116(1):20-32; discussion 33-5. doi: 10.1097/01.prs.0000169685.54862.18. PMID: 15988243
Use of misoprostol during pregnancy and Möbius' syndrome in infants.
Pastuszak AL, Schüler L, Speck-Martins CE, Coelho KE, Cordello SM, Vargas F, Brunoni D, Schwarz IV, Larrandaburu M, Safattle H, Meloni VF, Koren G
N Engl J Med 1998 Jun 25;338(26):1881-5. doi: 10.1056/NEJM199806253382604. PMID: 9637807

Diagnosis

Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or 'classical' congenital myopathy.
Zaharieva IT, Thor MG, Oates EC, van Karnebeek C, Hendson G, Blom E, Witting N, Rasmussen M, Gabbett MT, Ravenscroft G, Sframeli M, Suetterlin K, Sarkozy A, D'Argenzio L, Hartley L, Matthews E, Pitt M, Vissing J, Ballegaard M, Krarup C, Slørdahl A, Halvorsen H, Ye XC, Zhang LH, Løkken N, Werlauff U, Abdelsayed M, Davis MR, Feng L, Phadke R, Sewry CA, Morgan JE, Laing NG, Vallance H, Ruben P, Hanna MG, Lewis S, Kamsteeg EJ, Männikkö R, Muntoni F
Brain 2016 Mar;139(Pt 3):674-91. Epub 2015 Dec 22 doi: 10.1093/brain/awv352. PMID: 26700687Free PMC Article
Forceps Delivery-Related Ophthalmic Injuries: A Case Series.
McAnena L, O'Keefe M, Kirwan C, Murphy J
J Pediatr Ophthalmol Strabismus 2015 Nov-Dec;52(6):355-9. doi: 10.3928/01913913-20151014-50. PMID: 26584749
19q13.32 microdeletion syndrome: three new cases.
Castillo A, Kramer N, Schwartz CE, Miles JH, DuPont BR, Rosenfeld JA, Graham JM Jr
Eur J Med Genet 2014 Nov-Dec;57(11-12):654-8. Epub 2014 Sep 16 doi: 10.1016/j.ejmg.2014.08.009. PMID: 25230004
Developmental facial paralysis: a review.
Terzis JK, Anesti K
J Plast Reconstr Aesthet Surg 2011 Oct;64(10):1318-33. Epub 2011 Jul 2 doi: 10.1016/j.bjps.2011.04.015. PMID: 21724478
Use of misoprostol during pregnancy and Möbius' syndrome in infants.
Pastuszak AL, Schüler L, Speck-Martins CE, Coelho KE, Cordello SM, Vargas F, Brunoni D, Schwarz IV, Larrandaburu M, Safattle H, Meloni VF, Koren G
N Engl J Med 1998 Jun 25;338(26):1881-5. doi: 10.1056/NEJM199806253382604. PMID: 9637807

Therapy

Developmental unilateral facial palsy in a newborn: six cases and literature review.
Decraene L, Boudewyns A, Venstermans C, Ceulemans B
Eur J Pediatr 2020 Mar;179(3):367-375. Epub 2020 Jan 27 doi: 10.1007/s00431-019-03484-8. PMID: 31989259
Forceps Delivery-Related Ophthalmic Injuries: A Case Series.
McAnena L, O'Keefe M, Kirwan C, Murphy J
J Pediatr Ophthalmol Strabismus 2015 Nov-Dec;52(6):355-9. doi: 10.3928/01913913-20151014-50. PMID: 26584749
Autogenous fascia lata grafts: clinical applications in reanimation of the totally or partially paralyzed face.
Rose EH
Plast Reconstr Surg 2005 Jul;116(1):20-32; discussion 33-5. doi: 10.1097/01.prs.0000169685.54862.18. PMID: 15988243
Use of misoprostol during pregnancy and Möbius' syndrome in infants.
Pastuszak AL, Schüler L, Speck-Martins CE, Coelho KE, Cordello SM, Vargas F, Brunoni D, Schwarz IV, Larrandaburu M, Safattle H, Meloni VF, Koren G
N Engl J Med 1998 Jun 25;338(26):1881-5. doi: 10.1056/NEJM199806253382604. PMID: 9637807
Is permanent congenital facial palsy caused by birth trauma?
Laing JH, Harrison DH, Jones BM, Laing GJ
Arch Dis Child 1996 Jan;74(1):56-8. doi: 10.1136/adc.74.1.56. PMID: 8660050Free PMC Article

Prognosis

Developmental unilateral facial palsy in a newborn: six cases and literature review.
Decraene L, Boudewyns A, Venstermans C, Ceulemans B
Eur J Pediatr 2020 Mar;179(3):367-375. Epub 2020 Jan 27 doi: 10.1007/s00431-019-03484-8. PMID: 31989259
Forceps Delivery-Related Ophthalmic Injuries: A Case Series.
McAnena L, O'Keefe M, Kirwan C, Murphy J
J Pediatr Ophthalmol Strabismus 2015 Nov-Dec;52(6):355-9. doi: 10.3928/01913913-20151014-50. PMID: 26584749
Developmental facial paralysis: a review.
Terzis JK, Anesti K
J Plast Reconstr Aesthet Surg 2011 Oct;64(10):1318-33. Epub 2011 Jul 2 doi: 10.1016/j.bjps.2011.04.015. PMID: 21724478
Incidence of and risk factors for birth trauma in Iran.
Borna H, Rad SM, Borna S, Mohseni SM
Taiwan J Obstet Gynecol 2010 Jun;49(2):170-3. doi: 10.1016/S1028-4559(10)60036-8. PMID: 20708523
Facial nerve palsy in the newborn: incidence and outcome.
Falco NA, Eriksson E
Plast Reconstr Surg 1990 Jan;85(1):1-4. doi: 10.1097/00006534-199001000-00001. PMID: 2293714

Clinical prediction guides

Oral Health-Related Quality of Life in Rare Disorders of Congenital Facial Weakness.
Liberton DK, Almpani K, Mishra R, Bassim C, Van Ryzin C, On Behalf Of The Moebius Syndrome Research Consortium, Webb BD, Jabs EW, Engle EC, Collins FS, Manoli I, Lee JS
Int J Environ Res Public Health 2024 May 13;21(5) doi: 10.3390/ijerph21050615. PMID: 38791829Free PMC Article
Association between hypertensive disorders and Bell's palsy in pregnancy: protocol for a systematic review and meta-analysis.
Liu YN, Yang LY, Xue ZW, Zhou S
BMJ Open 2024 May 17;14(5):e080322. doi: 10.1136/bmjopen-2023-080322. PMID: 38760037Free PMC Article
Children with facial paralysis due to Moebius syndrome exhibit reduced autonomic modulation during emotion processing.
De Stefani E, Ardizzi M, Nicolini Y, Belluardo M, Barbot A, Bertolini C, Garofalo G, Bianchi B, Coudé G, Murray L, Ferrari PF
J Neurodev Disord 2019 Jul 10;11(1):12. doi: 10.1186/s11689-019-9272-2. PMID: 31291910Free PMC Article
Detection of varicella-zoster virus from cerebrospinal fluid using advanced fragment analysis in a child with encephalitis: a case report.
Song YX, Li Y, Jiang YM, Liu T
BMC Infect Dis 2019 Apr 25;19(1):342. doi: 10.1186/s12879-019-3986-3. PMID: 31023250Free PMC Article
Facial nerve palsy in the newborn: incidence and outcome.
Falco NA, Eriksson E
Plast Reconstr Surg 1990 Jan;85(1):1-4. doi: 10.1097/00006534-199001000-00001. PMID: 2293714

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