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Early Inflammatory Arthritis

MedGen UID:
858875
•Concept ID:
C3899281
•
Disease or Syndrome

Definition

Early stages of inflammatory arthritis, when the underlying diagnosis is uncertain, usually little or no joint damage has occurred. Treatment may alter the disease course (e.g., potentially avert progression to full RA or other diagnosis). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly Inflammatory Arthritis

Professional guidelines

PubMed

Impact of Adverse Events Associated With Medications in the Treatment and Prevention of Rheumatoid Arthritis.
Costello R, David T, Jani M
Clin Ther 2019 Jul;41(7):1376-1396. Epub 2019 Jun 10 doi: 10.1016/j.clinthera.2019.04.030. PMID: 31196653
The role of ultrasound in the diagnosis and follow-up of early inflammatory arthritis.
Spencer SP, Ganeshalingam S, Kelly S, Ahmad M
Clin Radiol 2012 Jan;67(1):15-23. Epub 2011 Aug 31 doi: 10.1016/j.crad.2011.03.025. PMID: 21885046
Using ultrasonography to facilitate best practice in diagnosis and management of RA.
Brown AK
Nat Rev Rheumatol 2009 Dec;5(12):698-706. Epub 2009 Nov 10 doi: 10.1038/nrrheum.2009.227. PMID: 19901917

Recent clinical studies

Etiology

The Expression of Inflammasomes NLRP1 and NLRP3, Toll-Like Receptors, and Vitamin D Receptor in Synovial Fibroblasts From Patients With Different Types of Knee Arthritis.
Sakalyte R, Denkovskij J, Bernotiene E, Stropuviene S, Mikulenaite SO, Kvederas G, Porvaneckas N, Tutkus V, Venalis A, Butrimiene I
Front Immunol 2021;12:767512. Epub 2022 Jan 19 doi: 10.3389/fimmu.2021.767512. PMID: 35126351Free PMC Article
Centre effects and case-mix in early rheumatoid arthritis observational cohorts: a narrative review.
Yates M, Bechman K, Norton S, Nikiphorou E, Galloway J
Rheumatology (Oxford) 2019 Nov 1;58(11):1991-1999. doi: 10.1093/rheumatology/kez151. PMID: 31329968Free PMC Article
The epidemiology of early inflammatory arthritis.
Hazes JM, Luime JJ
Nat Rev Rheumatol 2011 Jun 14;7(7):381-90. doi: 10.1038/nrrheum.2011.78. PMID: 21670767
Early inflammatory arthritis versus rheumatoid arthritis.
Finckh A
Curr Opin Rheumatol 2009 Mar;21(2):118-23. doi: 10.1097/BOR.0b013e3283235ac4. PMID: 19339921
Early rheumatoid arthritis.
Scott DL
Br Med Bull 2007;81-82:97-114. Epub 2007 May 31 doi: 10.1093/bmb/ldm011. PMID: 17540693

Diagnosis

The Expression of Inflammasomes NLRP1 and NLRP3, Toll-Like Receptors, and Vitamin D Receptor in Synovial Fibroblasts From Patients With Different Types of Knee Arthritis.
Sakalyte R, Denkovskij J, Bernotiene E, Stropuviene S, Mikulenaite SO, Kvederas G, Porvaneckas N, Tutkus V, Venalis A, Butrimiene I
Front Immunol 2021;12:767512. Epub 2022 Jan 19 doi: 10.3389/fimmu.2021.767512. PMID: 35126351Free PMC Article
The importance of ultrasound in identifying and differentiating patients with early inflammatory arthritis: a narrative review.
Kaeley GS, Bakewell C, Deodhar A
Arthritis Res Ther 2020 Jan 2;22(1):1. doi: 10.1186/s13075-019-2050-4. PMID: 31898524Free PMC Article
Centre effects and case-mix in early rheumatoid arthritis observational cohorts: a narrative review.
Yates M, Bechman K, Norton S, Nikiphorou E, Galloway J
Rheumatology (Oxford) 2019 Nov 1;58(11):1991-1999. doi: 10.1093/rheumatology/kez151. PMID: 31329968Free PMC Article
Early rheumatoid arthritis.
Scott DL
Br Med Bull 2007;81-82:97-114. Epub 2007 May 31 doi: 10.1093/bmb/ldm011. PMID: 17540693
Early rheumatoid arthritis.
Mitchell KL, Pisetsky DS
Curr Opin Rheumatol 2007 May;19(3):278-83. doi: 10.1097/BOR.0b013e32805e87bf. PMID: 17414956

Therapy

Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort.
Arnold MB, Bykerk VP, Boire G, Haraoui BP, Hitchon C, Thorne C, Keystone EC, Pope JE; CATCH Investigators
Rheumatology (Oxford) 2014 Jun;53(6):1075-86. doi: 10.1093/rheumatology/ket449. PMID: 24501240
Clinical approaches to early inflammatory arthritis.
van Schaardenburg D, Dijkmans BA
Nat Rev Rheumatol 2009 Nov;5(11):627-33. Epub 2009 Sep 29 doi: 10.1038/nrrheum.2009.203. PMID: 19786990
Early inflammatory arthritis versus rheumatoid arthritis.
Finckh A
Curr Opin Rheumatol 2009 Mar;21(2):118-23. doi: 10.1097/BOR.0b013e3283235ac4. PMID: 19339921
Early rheumatoid arthritis.
Scott DL
Br Med Bull 2007;81-82:97-114. Epub 2007 May 31 doi: 10.1093/bmb/ldm011. PMID: 17540693
Early rheumatoid arthritis.
Mitchell KL, Pisetsky DS
Curr Opin Rheumatol 2007 May;19(3):278-83. doi: 10.1097/BOR.0b013e32805e87bf. PMID: 17414956

Prognosis

Autoantibody and metalloproteinase activity in early arthritis.
Ponikowska M, Świerkot J, Nowak B, Korman L, Wiland P
Clin Rheumatol 2019 Mar;38(3):827-834. Epub 2018 Nov 7 doi: 10.1007/s10067-018-4326-5. PMID: 30406565
The role of ultrasound in the diagnosis and follow-up of early inflammatory arthritis.
Spencer SP, Ganeshalingam S, Kelly S, Ahmad M
Clin Radiol 2012 Jan;67(1):15-23. Epub 2011 Aug 31 doi: 10.1016/j.crad.2011.03.025. PMID: 21885046
The epidemiology of early inflammatory arthritis.
Hazes JM, Luime JJ
Nat Rev Rheumatol 2011 Jun 14;7(7):381-90. doi: 10.1038/nrrheum.2011.78. PMID: 21670767
Early inflammatory arthritis versus rheumatoid arthritis.
Finckh A
Curr Opin Rheumatol 2009 Mar;21(2):118-23. doi: 10.1097/BOR.0b013e3283235ac4. PMID: 19339921
Early rheumatoid arthritis.
Mitchell KL, Pisetsky DS
Curr Opin Rheumatol 2007 May;19(3):278-83. doi: 10.1097/BOR.0b013e32805e87bf. PMID: 17414956

Clinical prediction guides

The Expression of Inflammasomes NLRP1 and NLRP3, Toll-Like Receptors, and Vitamin D Receptor in Synovial Fibroblasts From Patients With Different Types of Knee Arthritis.
Sakalyte R, Denkovskij J, Bernotiene E, Stropuviene S, Mikulenaite SO, Kvederas G, Porvaneckas N, Tutkus V, Venalis A, Butrimiene I
Front Immunol 2021;12:767512. Epub 2022 Jan 19 doi: 10.3389/fimmu.2021.767512. PMID: 35126351Free PMC Article
Centre effects and case-mix in early rheumatoid arthritis observational cohorts: a narrative review.
Yates M, Bechman K, Norton S, Nikiphorou E, Galloway J
Rheumatology (Oxford) 2019 Nov 1;58(11):1991-1999. doi: 10.1093/rheumatology/kez151. PMID: 31329968Free PMC Article
Clinical approaches to early inflammatory arthritis.
van Schaardenburg D, Dijkmans BA
Nat Rev Rheumatol 2009 Nov;5(11):627-33. Epub 2009 Sep 29 doi: 10.1038/nrrheum.2009.203. PMID: 19786990
Early rheumatoid arthritis.
Scott DL
Br Med Bull 2007;81-82:97-114. Epub 2007 May 31 doi: 10.1093/bmb/ldm011. PMID: 17540693
Early rheumatoid arthritis.
Mitchell KL, Pisetsky DS
Curr Opin Rheumatol 2007 May;19(3):278-83. doi: 10.1097/BOR.0b013e32805e87bf. PMID: 17414956

Recent systematic reviews

Baseline patient reported outcomes are more consistent predictors of long-term functional disability than laboratory, imaging or joint count data in patients with early inflammatory arthritis: A systematic review.
Gwinnutt JM, Sharp CA, Symmons DPM, Lunt M, Verstappen SMM
Semin Arthritis Rheum 2018 Dec;48(3):384-398. Epub 2018 Mar 15 doi: 10.1016/j.semarthrit.2018.03.004. PMID: 29680162Free PMC Article
Lack of seroconversion of rheumatoid factor and anti-cyclic citrullinated peptide in patients with early inflammatory arthritis: a systematic literature review.
Barra L, Pope J, Bessette L, Haraoui B, Bykerk V
Rheumatology (Oxford) 2011 Feb;50(2):311-6. Epub 2010 Jul 9 doi: 10.1093/rheumatology/keq190. PMID: 20621983

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