U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Calcineurin Nephrotoxicity

MedGen UID:
859325
Concept ID:
C3899731
Disease or Syndrome
Synonym: Calcineurin Inhibitor Nephrotoxicity

Definition

Kidney injury caused by calcineurin inhibitor immunosuppressive therapy which may lead to diminished kidney function. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCalcineurin Nephrotoxicity

Professional guidelines

PubMed

Madariaga HM, Riella LV
Contrib Nephrol 2017;190:168-180. Epub 2017 May 23 doi: 10.1159/000468963. PMID: 28535528
Pham PT, Pham PC, Wilkinson AH
Curr Opin Organ Transplant 2009 Jun;14(3):231-9. doi: 10.1097/MOT.0b013e32832b34a4. PMID: 19395967

Recent clinical studies

Etiology

Madariaga HM, Riella LV
Contrib Nephrol 2017;190:168-180. Epub 2017 May 23 doi: 10.1159/000468963. PMID: 28535528
Ventura-Aguiar P, Campistol JM, Diekmann F
Expert Opin Drug Saf 2016;15(3):303-19. Epub 2016 Jan 28 doi: 10.1517/14740338.2016.1132698. PMID: 26667069
Raichlin E, Daly RC, Rosen CB, McGregor CG, Charlton MR, Frantz RP, Clavell AL, Rodeheffer RJ, Pereira NL, Kremers WK, Kushwaha SS, Edwards BS
Transplantation 2009 Jul 27;88(2):219-25. doi: 10.1097/TP.0b013e3181ac60db. PMID: 19623017
Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR
Transplantation 2004 Aug 15;78(3):461-8. doi: 10.1097/01.tp.0000128612.75163.26. PMID: 15316377
Joosten SA, van Kooten C, Sijpkens YW, de Fijter JW, Paul LC
Kidney Int 2004 May;65(5):1556-9. doi: 10.1111/j.1523-1755.2004.05410.x. PMID: 15086891

Diagnosis

Gavela E, Pallardó LM, Sancho A, Avilla A, Beltrán S, Roselló E, Pérez ML, García F
Transplant Proc 2009 Jul-Aug;41(6):2099-101. doi: 10.1016/j.transproceed.2009.06.058. PMID: 19715842
Raichlin E, Daly RC, Rosen CB, McGregor CG, Charlton MR, Frantz RP, Clavell AL, Rodeheffer RJ, Pereira NL, Kremers WK, Kushwaha SS, Edwards BS
Transplantation 2009 Jul 27;88(2):219-25. doi: 10.1097/TP.0b013e3181ac60db. PMID: 19623017
Araya CE, Fennell RS, Neiberger RE, Dharnidharka VR
Clin J Am Soc Nephrol 2006 Nov;1(6):1161-6. Epub 2006 Aug 30 doi: 10.2215/CJN.01520506. PMID: 17699342

Therapy

Ventura-Aguiar P, Campistol JM, Diekmann F
Expert Opin Drug Saf 2016;15(3):303-19. Epub 2016 Jan 28 doi: 10.1517/14740338.2016.1132698. PMID: 26667069
Sutherland AI, Akhtar MZ, Zilvetti M, Brockmann J, Ruse S, Fuggle SV, Sinha S, Harden P, Friend PJ
Am J Transplant 2014 Mar;14(3):677-84. doi: 10.1111/ajt.12572. PMID: 24612687
Williams D, Haragsim L
Adv Chronic Kidney Dis 2006 Jan;13(1):47-55. doi: 10.1053/j.ackd.2005.11.001. PMID: 16412970
Pillebout E, Nochy D, Hill G, Conti F, Antoine C, Calmus Y, Glotz D
Am J Transplant 2005 May;5(5):1120-9. doi: 10.1111/j.1600-6143.2005.00852.x. PMID: 15816895
Joosten SA, van Kooten C, Sijpkens YW, de Fijter JW, Paul LC
Kidney Int 2004 May;65(5):1556-9. doi: 10.1111/j.1523-1755.2004.05410.x. PMID: 15086891

Prognosis

Sutherland AI, Akhtar MZ, Zilvetti M, Brockmann J, Ruse S, Fuggle SV, Sinha S, Harden P, Friend PJ
Am J Transplant 2014 Mar;14(3):677-84. doi: 10.1111/ajt.12572. PMID: 24612687
Gavela E, Pallardó LM, Sancho A, Avilla A, Beltrán S, Roselló E, Pérez ML, García F
Transplant Proc 2009 Jul-Aug;41(6):2099-101. doi: 10.1016/j.transproceed.2009.06.058. PMID: 19715842
Raichlin E, Daly RC, Rosen CB, McGregor CG, Charlton MR, Frantz RP, Clavell AL, Rodeheffer RJ, Pereira NL, Kremers WK, Kushwaha SS, Edwards BS
Transplantation 2009 Jul 27;88(2):219-25. doi: 10.1097/TP.0b013e3181ac60db. PMID: 19623017
Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR
Transplantation 2004 Aug 15;78(3):461-8. doi: 10.1097/01.tp.0000128612.75163.26. PMID: 15316377

Clinical prediction guides

Gavela E, Pallardó LM, Sancho A, Avilla A, Beltrán S, Roselló E, Pérez ML, García F
Transplant Proc 2009 Jul-Aug;41(6):2099-101. doi: 10.1016/j.transproceed.2009.06.058. PMID: 19715842
Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR
Transplantation 2004 Aug 15;78(3):461-8. doi: 10.1097/01.tp.0000128612.75163.26. PMID: 15316377

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...