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Early-onset hepatocellular carcinoma

MedGen UID:
863900
•Concept ID:
C4015463
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly-onset hepatocellular carcinoma

Professional guidelines

PubMed

Molecular characterization of hepatitis B virus (HBV) in African children living in Australia identifies genotypes and variants associated with poor clinical outcome.
Bannister EG, Yuen L, Littlejohn M, Edwards R, Sozzi V, Colledge D, Li X, Locarnini S, Hardikar W, Revill PA
J Gen Virol 2018 Aug;99(8):1103-1114. Epub 2018 Jun 22 doi: 10.1099/jgv.0.001086. PMID: 29932395
Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma.
Yan H, Yang Y, Zhang L, Tang G, Wang Y, Xue G, Zhou W, Sun S
Hepatology 2015 Jun;61(6):1821-31. Epub 2015 Mar 18 doi: 10.1002/hep.27722. PMID: 25627239

Recent clinical studies

Etiology

Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations.
Zuckerman JT, Minko IG, Kant M, Jaruga P, Stone MP, Dizdaroglu M, McCullough AK, Lloyd RS
DNA Repair (Amst) 2023 Sep;129:103544. Epub 2023 Jul 20 doi: 10.1016/j.dnarep.2023.103544. PMID: 37517321Free PMC Article
Liver Disease and Risk of Hepatocellular Carcinoma in Children With Mutations in TALDO1.
Grammatikopoulos T, Hadzic N, Foskett P, Strautnieks S, Samyn M, Vara R, Dhawan A, Hertecant J, Al Jasmi F, Rahman O, Deheragoda M, Bull LN, Thompson RJ; University of Washington Center for Mendelian Genomics
Hepatol Commun 2022 Mar;6(3):473-479. Epub 2021 Oct 22 doi: 10.1002/hep4.1824. PMID: 34677006Free PMC Article
Genome-wide identification of blood DNA methylation patterns associated with early-onset hepatocellular carcinoma development in hepatitis B carriers.
Kao WY, Yang SH, Liu WJ, Yeh MY, Lin CL, Liu CJ, Huang CJ, Lin SM, Lee SD, Chen PJ, Yu MW
Mol Carcinog 2017 Feb;56(2):425-435. Epub 2016 Jun 10 doi: 10.1002/mc.22505. PMID: 27254796
Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma.
Yan H, Yang Y, Zhang L, Tang G, Wang Y, Xue G, Zhou W, Sun S
Hepatology 2015 Jun;61(6):1821-31. Epub 2015 Mar 18 doi: 10.1002/hep.27722. PMID: 25627239
Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct.
Lin YC, Li L, Makarova AV, Burgers PM, Stone MP, Lloyd RS
Carcinogenesis 2014 Jul;35(7):1461-8. Epub 2014 Jan 7 doi: 10.1093/carcin/bgu003. PMID: 24398669Free PMC Article

Diagnosis

Liver Disease and Risk of Hepatocellular Carcinoma in Children With Mutations in TALDO1.
Grammatikopoulos T, Hadzic N, Foskett P, Strautnieks S, Samyn M, Vara R, Dhawan A, Hertecant J, Al Jasmi F, Rahman O, Deheragoda M, Bull LN, Thompson RJ; University of Washington Center for Mendelian Genomics
Hepatol Commun 2022 Mar;6(3):473-479. Epub 2021 Oct 22 doi: 10.1002/hep4.1824. PMID: 34677006Free PMC Article
Adult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency.
Stender S, Chakrabarti RS, Xing C, Gotway G, Cohen JC, Hobbs HH
Mol Genet Metab 2015 Dec;116(4):269-74. Epub 2015 Oct 26 doi: 10.1016/j.ymgme.2015.10.009. PMID: 26527160Free PMC Article

Therapy

Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct.
Lin YC, Li L, Makarova AV, Burgers PM, Stone MP, Lloyd RS
Carcinogenesis 2014 Jul;35(7):1461-8. Epub 2014 Jan 7 doi: 10.1093/carcin/bgu003. PMID: 24398669Free PMC Article

Prognosis

Liver Disease and Risk of Hepatocellular Carcinoma in Children With Mutations in TALDO1.
Grammatikopoulos T, Hadzic N, Foskett P, Strautnieks S, Samyn M, Vara R, Dhawan A, Hertecant J, Al Jasmi F, Rahman O, Deheragoda M, Bull LN, Thompson RJ; University of Washington Center for Mendelian Genomics
Hepatol Commun 2022 Mar;6(3):473-479. Epub 2021 Oct 22 doi: 10.1002/hep4.1824. PMID: 34677006Free PMC Article
Genome-wide identification of blood DNA methylation patterns associated with early-onset hepatocellular carcinoma development in hepatitis B carriers.
Kao WY, Yang SH, Liu WJ, Yeh MY, Lin CL, Liu CJ, Huang CJ, Lin SM, Lee SD, Chen PJ, Yu MW
Mol Carcinog 2017 Feb;56(2):425-435. Epub 2016 Jun 10 doi: 10.1002/mc.22505. PMID: 27254796
Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma.
Yan H, Yang Y, Zhang L, Tang G, Wang Y, Xue G, Zhou W, Sun S
Hepatology 2015 Jun;61(6):1821-31. Epub 2015 Mar 18 doi: 10.1002/hep.27722. PMID: 25627239

Clinical prediction guides

Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations.
Zuckerman JT, Minko IG, Kant M, Jaruga P, Stone MP, Dizdaroglu M, McCullough AK, Lloyd RS
DNA Repair (Amst) 2023 Sep;129:103544. Epub 2023 Jul 20 doi: 10.1016/j.dnarep.2023.103544. PMID: 37517321Free PMC Article
Liver Disease and Risk of Hepatocellular Carcinoma in Children With Mutations in TALDO1.
Grammatikopoulos T, Hadzic N, Foskett P, Strautnieks S, Samyn M, Vara R, Dhawan A, Hertecant J, Al Jasmi F, Rahman O, Deheragoda M, Bull LN, Thompson RJ; University of Washington Center for Mendelian Genomics
Hepatol Commun 2022 Mar;6(3):473-479. Epub 2021 Oct 22 doi: 10.1002/hep4.1824. PMID: 34677006Free PMC Article
Genome-wide identification of blood DNA methylation patterns associated with early-onset hepatocellular carcinoma development in hepatitis B carriers.
Kao WY, Yang SH, Liu WJ, Yeh MY, Lin CL, Liu CJ, Huang CJ, Lin SM, Lee SD, Chen PJ, Yu MW
Mol Carcinog 2017 Feb;56(2):425-435. Epub 2016 Jun 10 doi: 10.1002/mc.22505. PMID: 27254796

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