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Abnormal ductus choledochus morphology

MedGen UID:
866598
•Concept ID:
C4020944
•
Anatomical Abnormality
Synonyms: Abnormality of the common bile duct; Abnormality of the ductus choledochus
 
HPO: HP:0100889

Definition

An abnormality of the Common bile duct, a tube-like anatomic structure in the human gastrointestinal tract, formed by the union of the Common hepatic duct and the Cystic duct from the gall bladder. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal ductus choledochus morphology

Professional guidelines

PubMed

Diagnosis and treatment of pancreas divisum: A literature review.
Ferri V, Vicente E, Quijano Y, Ielpo B, Duran H, Diaz E, Fabra I, Caruso R
Hepatobiliary Pancreat Dis Int 2019 Aug;18(4):332-336. Epub 2019 May 20 doi: 10.1016/j.hbpd.2019.05.004. PMID: 31155429
Japanese clinical practice guidelines for congenital biliary dilatation.
Ishibashi H, Shimada M, Kamisawa T, Fujii H, Hamada Y, Kubota M, Urushihara N, Endo I, Nio M, Taguchi T, Ando H; Japanese Study Group on Congenital Biliary Dilatation (JSCBD)
J Hepatobiliary Pancreat Sci 2017 Jan;24(1):1-16. Epub 2017 Jan 22 doi: 10.1002/jhbp.415. PMID: 28111910
Biliary cysts: etiology, diagnosis and management.
Jabłońska B
World J Gastroenterol 2012 Sep 21;18(35):4801-10. doi: 10.3748/wjg.v18.i35.4801. PMID: 23002354Free PMC Article

Recent clinical studies

Etiology

Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia.
Amarachintha SP, Mourya R, Ayabe H, Yang L, Luo Z, Li X, Thanekar U, Shivakumar P, Bezerra JA
Hepatology 2022 Jan;75(1):89-103. Epub 2021 Dec 4 doi: 10.1002/hep.32107. PMID: 34392560Free PMC Article
Biliary carcinogenesis in pancreaticobiliary maljunction.
Kamisawa T, Kuruma S, Chiba K, Tabata T, Koizumi S, Kikuyama M
J Gastroenterol 2017 Feb;52(2):158-163. Epub 2016 Oct 4 doi: 10.1007/s00535-016-1268-z. PMID: 27704265
Imaging of choledochal cysts.
Lewis VA, Adam SZ, Nikolaidis P, Wood C, Wu JG, Yaghmai V, Miller FH
Abdom Imaging 2015 Aug;40(6):1567-80. doi: 10.1007/s00261-015-0381-4. PMID: 25682292
Gallbladder cancer.
Wernberg JA, Lucarelli DD
Surg Clin North Am 2014 Apr;94(2):343-60. Epub 2014 Feb 18 doi: 10.1016/j.suc.2014.01.009. PMID: 24679425
Biliary atresia revisited.
Kahn E
Pediatr Dev Pathol 2004 Mar-Apr;7(2):109-24. Epub 2004 Mar 4 doi: 10.1007/s10024-003-0307-y. PMID: 14994122

Diagnosis

Biliary Atresia - emerging diagnostic and therapy opportunities.
Lendahl U, Lui VCH, Chung PHY, Tam PKH
EBioMedicine 2021 Dec;74:103689. Epub 2021 Nov 12 doi: 10.1016/j.ebiom.2021.103689. PMID: 34781099Free PMC Article
Pancreaticobiliary maljunction.
Kamisawa T, Takuma K, Anjiki H, Egawa N, Kurata M, Honda G, Tsuruta K, Sasaki T
Clin Gastroenterol Hepatol 2009 Nov;7(11 Suppl):S84-8. doi: 10.1016/j.cgh.2009.08.024. PMID: 19896105
Biliary atresia revisited.
Kahn E
Pediatr Dev Pathol 2004 Mar-Apr;7(2):109-24. Epub 2004 Mar 4 doi: 10.1007/s10024-003-0307-y. PMID: 14994122
Congenital biliary dilatation.
Miyano T, Yamataka A, Li L
Semin Pediatr Surg 2000 Nov;9(4):187-95. doi: 10.1053/spsu.2000.18843. PMID: 11112836
Biliary atresia.
Lefkowitch JH
Mayo Clin Proc 1998 Jan;73(1):90-5. doi: 10.1016/S0025-6196(11)63625-2. PMID: 9443685

Therapy

Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V, Kwong LN, Rodon J, Javle M, Meric-Bernstam F
J Hepatol 2024 Feb;80(2):322-334. Epub 2023 Nov 14 doi: 10.1016/j.jhep.2023.10.041. PMID: 37972659
History!
Nayak LJ, Sondhi AR, Westerhoff M
Gastroenterology 2021 May;160(6):e5-e6. Epub 2020 Oct 8 doi: 10.1053/j.gastro.2020.09.048. PMID: 33039473
Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Pancreaticobiliary maljunction.
Kamisawa T, Takuma K, Anjiki H, Egawa N, Kurata M, Honda G, Tsuruta K, Sasaki T
Clin Gastroenterol Hepatol 2009 Nov;7(11 Suppl):S84-8. doi: 10.1016/j.cgh.2009.08.024. PMID: 19896105

Prognosis

Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Gallbladder cancer.
Wernberg JA, Lucarelli DD
Surg Clin North Am 2014 Apr;94(2):343-60. Epub 2014 Feb 18 doi: 10.1016/j.suc.2014.01.009. PMID: 24679425
Pancreas divisum.
DiMagno MJ, Wamsteker EJ
Curr Gastroenterol Rep 2011 Apr;13(2):150-6. doi: 10.1007/s11894-010-0170-8. PMID: 21222060Free PMC Article
Biliary atresia.
Mieli-Vergani G, Vergani D
Semin Immunopathol 2009 Sep;31(3):371-81. Epub 2009 Jun 17 doi: 10.1007/s00281-009-0171-6. PMID: 19533128
Idiopathic chronic pancreatitis.
Keller J, Layer P
Best Pract Res Clin Gastroenterol 2008;22(1):105-13. doi: 10.1016/j.bpg.2007.10.006. PMID: 18206816

Clinical prediction guides

A preoperative scoring system to predict lymph node metastasis in intrahepatic cholangiocarcinoma.
Rhee H, Lim HJ, Han K, Yeom SK, Choi SH, Park JH, Cho ES, Park S, Lee MJ, Choi GH, Han DH, Lee SS, Park MS
Hepatol Int 2023 Aug;17(4):942-953. Epub 2023 Jan 23 doi: 10.1007/s12072-022-10477-7. PMID: 36689090
Circular RNAs in cholangiocarcinoma.
Liao W, Feng Q, Liu H, Du J, Chen X, Zeng Y
Cancer Lett 2023 Jan 28;553:215980. Epub 2022 Nov 4 doi: 10.1016/j.canlet.2022.215980. PMID: 36336149
The cholangiocyte primary cilium in health and disease.
Mansini AP, Peixoto E, Thelen KM, Gaspari C, Jin S, Gradilone SA
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1245-1253. Epub 2017 Jun 15 doi: 10.1016/j.bbadis.2017.06.006. PMID: 28625917Free PMC Article
"Biliary Diseases with Pancreatic Counterparts": Cross-sectional Imaging Findings.
Katabathina VS, Flaherty EM, Dasyam AK, Menias CO, Riddle ND, Lath N, Kozaka K, Matsui O, Nakanuma Y, Prasad SR
Radiographics 2016 Mar-Apr;36(2):374-92. Epub 2016 Feb 1 doi: 10.1148/rg.2016150071. PMID: 26824512
Pancreas divisum.
DiMagno MJ, Wamsteker EJ
Curr Gastroenterol Rep 2011 Apr;13(2):150-6. doi: 10.1007/s11894-010-0170-8. PMID: 21222060Free PMC Article

Recent systematic reviews

Association of mucin family members with prognostic significance in pancreatic cancer patients: A meta-analysis.
Xu W, Zhang M, Liu L, Yin M, Xu C, Weng Z
PLoS One 2022;17(6):e0269612. Epub 2022 Jun 16 doi: 10.1371/journal.pone.0269612. PMID: 35709153Free PMC Article
Defining an optimal surveillance strategy for patients following choledochal cyst resection: results of a systematic review.
Koea J, O'Grady M, Agraval J, Srinivasa S
ANZ J Surg 2022 Jun;92(6):1356-1364. Epub 2022 May 17 doi: 10.1111/ans.17775. PMID: 35579057
Therapeutic approaches for portal biliopathy: A systematic review.
Franceschet I, Zanetto A, Ferrarese A, Burra P, Senzolo M
World J Gastroenterol 2016 Dec 7;22(45):9909-9920. doi: 10.3748/wjg.v22.i45.9909. PMID: 28018098Free PMC Article
Utility of fluorescent cholangiography during laparoscopic cholecystectomy: A systematic review.
Pesce A, Piccolo G, La Greca G, Puleo S
World J Gastroenterol 2015 Jul 7;21(25):7877-83. doi: 10.3748/wjg.v21.i25.7877. PMID: 26167088Free PMC Article
Postoperative biliary adverse events following orthotopic liver transplantation: assessment with magnetic resonance cholangiography.
Boraschi P, Donati F
World J Gastroenterol 2014 Aug 28;20(32):11080-94. doi: 10.3748/wjg.v20.i32.11080. PMID: 25170197Free PMC Article

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