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Abnormal biliary tract morphology

MedGen UID:
866739
•Concept ID:
C4021086
•
Anatomical Abnormality
Synonym: Anomaly of the biliary tract
 
HPO: HP:0012440

Definition

A structural abnormality of the biliary tree. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Abnormal biliary tract morphology

Professional guidelines

PubMed

Prenatal sonographic diagnosis of biliary tract malformations.
Koukoura O, Kelesidou V, Delianidou M, Athanasiadis A, Dagklis T
J Clin Ultrasound 2019 Jun;47(5):292-297. Epub 2019 Feb 6 doi: 10.1002/jcu.22705. PMID: 30729537
Japanese clinical practice guidelines for congenital biliary dilatation.
Ishibashi H, Shimada M, Kamisawa T, Fujii H, Hamada Y, Kubota M, Urushihara N, Endo I, Nio M, Taguchi T, Ando H; Japanese Study Group on Congenital Biliary Dilatation (JSCBD)
J Hepatobiliary Pancreat Sci 2017 Jan;24(1):1-16. Epub 2017 Jan 22 doi: 10.1002/jhbp.415. PMID: 28111910
Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Fawaz R, Baumann U, Ekong U, Fischler B, Hadzic N, Mack CL, McLin VA, Molleston JP, Neimark E, Ng VL, Karpen SJ
J Pediatr Gastroenterol Nutr 2017 Jan;64(1):154-168. doi: 10.1097/MPG.0000000000001334. PMID: 27429428

Recent clinical studies

Etiology

Imaging of Biliary Tree Abnormalities.
Lopes Vendrami C, Thorson DL, Borhani AA, Mittal PK, Hammond NA, Escobar DJ, Gabriel H, Recht HS, Horowitz JM, Kelahan LC, Wood CG, Nikolaidis P, Venkatesh SK, Miller FH
Radiographics 2024 Aug;44(8):e230174. doi: 10.1148/rg.230174. PMID: 39024175
Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia.
Amarachintha SP, Mourya R, Ayabe H, Yang L, Luo Z, Li X, Thanekar U, Shivakumar P, Bezerra JA
Hepatology 2022 Jan;75(1):89-103. Epub 2021 Dec 4 doi: 10.1002/hep.32107. PMID: 34392560Free PMC Article
Biliary carcinogenesis in pancreaticobiliary maljunction.
Kamisawa T, Kuruma S, Chiba K, Tabata T, Koizumi S, Kikuyama M
J Gastroenterol 2017 Feb;52(2):158-163. Epub 2016 Oct 4 doi: 10.1007/s00535-016-1268-z. PMID: 27704265
Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Imaging of choledochal cysts.
Lewis VA, Adam SZ, Nikolaidis P, Wood C, Wu JG, Yaghmai V, Miller FH
Abdom Imaging 2015 Aug;40(6):1567-80. doi: 10.1007/s00261-015-0381-4. PMID: 25682292

Diagnosis

Imaging in Pediatric Obstructive Jaundice.
Jain R, Gupta A, Kandasamy D, Jana M
Indian J Pediatr 2022 Sep;89(9):899-907. Epub 2022 Jun 2 doi: 10.1007/s12098-022-04171-7. PMID: 35653074
Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Understanding choledochal malformation.
Makin E, Davenport M
Arch Dis Child 2012 Jan;97(1):69-72. Epub 2011 Mar 27 doi: 10.1136/adc.2010.195974. PMID: 21444296
Pancreaticobiliary maljunction.
Kamisawa T, Takuma K, Anjiki H, Egawa N, Kurata M, Honda G, Tsuruta K, Sasaki T
Clin Gastroenterol Hepatol 2009 Nov;7(11 Suppl):S84-8. doi: 10.1016/j.cgh.2009.08.024. PMID: 19896105
Congenital biliary dilatation.
Miyano T, Yamataka A, Li L
Semin Pediatr Surg 2000 Nov;9(4):187-95. doi: 10.1053/spsu.2000.18843. PMID: 11112836

Therapy

Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V, Kwong LN, Rodon J, Javle M, Meric-Bernstam F
J Hepatol 2024 Feb;80(2):322-334. Epub 2023 Nov 14 doi: 10.1016/j.jhep.2023.10.041. PMID: 37972659
History!
Nayak LJ, Sondhi AR, Westerhoff M
Gastroenterology 2021 May;160(6):e5-e6. Epub 2020 Oct 8 doi: 10.1053/j.gastro.2020.09.048. PMID: 33039473
Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Pancreaticobiliary maljunction.
Kamisawa T, Takuma K, Anjiki H, Egawa N, Kurata M, Honda G, Tsuruta K, Sasaki T
Clin Gastroenterol Hepatol 2009 Nov;7(11 Suppl):S84-8. doi: 10.1016/j.cgh.2009.08.024. PMID: 19896105

Prognosis

Imaging of Biliary Tree Abnormalities.
Lopes Vendrami C, Thorson DL, Borhani AA, Mittal PK, Hammond NA, Escobar DJ, Gabriel H, Recht HS, Horowitz JM, Kelahan LC, Wood CG, Nikolaidis P, Venkatesh SK, Miller FH
Radiographics 2024 Aug;44(8):e230174. doi: 10.1148/rg.230174. PMID: 39024175
Prenatal sonographic diagnosis of biliary tract malformations.
Koukoura O, Kelesidou V, Delianidou M, Athanasiadis A, Dagklis T
J Clin Ultrasound 2019 Jun;47(5):292-297. Epub 2019 Feb 6 doi: 10.1002/jcu.22705. PMID: 30729537
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
MicroRNAs and benign biliary tract diseases.
Gradilone SA, O'Hara SP, Masyuk TV, Pisarello MJ, LaRusso NF
Semin Liver Dis 2015 Feb;35(1):26-35. Epub 2015 Jan 29 doi: 10.1055/s-0034-1397346. PMID: 25632932Free PMC Article
Biliary atresia.
Mieli-Vergani G, Vergani D
Semin Immunopathol 2009 Sep;31(3):371-81. Epub 2009 Jun 17 doi: 10.1007/s00281-009-0171-6. PMID: 19533128

Clinical prediction guides

A preoperative scoring system to predict lymph node metastasis in intrahepatic cholangiocarcinoma.
Rhee H, Lim HJ, Han K, Yeom SK, Choi SH, Park JH, Cho ES, Park S, Lee MJ, Choi GH, Han DH, Lee SS, Park MS
Hepatol Int 2023 Aug;17(4):942-953. Epub 2023 Jan 23 doi: 10.1007/s12072-022-10477-7. PMID: 36689090
The cholangiocyte primary cilium in health and disease.
Mansini AP, Peixoto E, Thelen KM, Gaspari C, Jin S, Gradilone SA
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1245-1253. Epub 2017 Jun 15 doi: 10.1016/j.bbadis.2017.06.006. PMID: 28625917Free PMC Article
Molecular genetics and targeted therapeutics in biliary tract carcinoma.
Marks EI, Yee NS
World J Gastroenterol 2016 Jan 28;22(4):1335-47. doi: 10.3748/wjg.v22.i4.1335. PMID: 26819503Free PMC Article
Gallbladder volvulus.
Arslan ED, Hakbilir O, Uyanik B, Oztürk B, Kaya E, Oztürk D
J Pak Med Assoc 2012 Sep;62(9):965-6. PMID: 23139986
Hepatobiliary pathology.
Lefkowitch JH
Curr Opin Gastroenterol 2005 May;21(3):260-9. doi: 10.1097/01.mog.0000159820.78532.68. PMID: 15818145

Recent systematic reviews

Association of mucin family members with prognostic significance in pancreatic cancer patients: A meta-analysis.
Xu W, Zhang M, Liu L, Yin M, Xu C, Weng Z
PLoS One 2022;17(6):e0269612. Epub 2022 Jun 16 doi: 10.1371/journal.pone.0269612. PMID: 35709153Free PMC Article
Risk of malignancy in Caroli disease and syndrome: A systematic review.
Fahrner R, Dennler SG, Inderbitzin D
World J Gastroenterol 2020 Aug 21;26(31):4718-4728. doi: 10.3748/wjg.v26.i31.4718. PMID: 32884228Free PMC Article
Utility of fluorescent cholangiography during laparoscopic cholecystectomy: A systematic review.
Pesce A, Piccolo G, La Greca G, Puleo S
World J Gastroenterol 2015 Jul 7;21(25):7877-83. doi: 10.3748/wjg.v21.i25.7877. PMID: 26167088Free PMC Article
Postoperative biliary adverse events following orthotopic liver transplantation: assessment with magnetic resonance cholangiography.
Boraschi P, Donati F
World J Gastroenterol 2014 Aug 28;20(32):11080-94. doi: 10.3748/wjg.v20.i32.11080. PMID: 25170197Free PMC Article
Routine histological analysis of a macroscopically normal gallbladder--a review of the literature.
Jamal K, Ratansingham K, Siddique M, Nehra D
Int J Surg 2014;12(9):958-62. Epub 2014 Jul 22 doi: 10.1016/j.ijsu.2014.07.010. PMID: 25058481

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