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Abnormal tendon morphology

MedGen UID:
866679
•Concept ID:
C4021026
•
Anatomical Abnormality
Synonyms: Abnormal shape of tendon; Abnormality of the sinew
 
HPO: HP:0100261

Definition

An abnormality of the structure or form of the tendons, also often called sinews. [from HPO]

Professional guidelines

PubMed

HMGB1: a potential new target for tendinopathy treatment.
Lu P, Li Y, Dai G, Zhang Y, Shi L, Zhang M, Wang H, Rui Y
Connect Tissue Res 2023 Jul;64(4):362-375. Epub 2023 Apr 9 doi: 10.1080/03008207.2023.2199089. PMID: 37032550
Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
Challenges of heterotopic ossification-Molecular background and current treatment strategies.
Łęgosz P, Drela K, Pulik Ł, Sarzyńska S, Małdyk P
Clin Exp Pharmacol Physiol 2018 Dec;45(12):1229-1235. Epub 2018 Oct 4 doi: 10.1111/1440-1681.13025. PMID: 30144316

Recent clinical studies

Etiology

HMGB1: a potential new target for tendinopathy treatment.
Lu P, Li Y, Dai G, Zhang Y, Shi L, Zhang M, Wang H, Rui Y
Connect Tissue Res 2023 Jul;64(4):362-375. Epub 2023 Apr 9 doi: 10.1080/03008207.2023.2199089. PMID: 37032550
Tendon appearance at imaging may be altered, but it may not indicate pathology.
Maffulli N, Nilsson Helander K, Migliorini F
Knee Surg Sports Traumatol Arthrosc 2023 May;31(5):1625-1628. Epub 2023 Feb 17 doi: 10.1007/s00167-023-07339-6. PMID: 36800008
Achilles Tendon, Patellar Tendon, and Femoral Cartilage Thickness in Control vs Asymptomatic Flatfoot Young Adults.
Taş S, Aktaş A, Dikici TF, Çekok FK
Foot Ankle Int 2023 Jan;44(1):81-88. Epub 2022 Nov 22 doi: 10.1177/10711007221136137. PMID: 36412188
Tenosynovial and Cardiac Amyloidosis in Patients Undergoing Carpal Tunnel Release.
Sperry BW, Reyes BA, Ikram A, Donnelly JP, Phelan D, Jaber WA, Shapiro D, Evans PJ, Maschke S, Kilpatrick SE, Tan CD, Rodriguez ER, Monteiro C, Tang WHW, Kelly JW, Seitz WH Jr, Hanna M
J Am Coll Cardiol 2018 Oct 23;72(17):2040-2050. doi: 10.1016/j.jacc.2018.07.092. PMID: 30336828
Jumper's knee.
Ferretti A, Ippolito E, Mariani P, Puddu G
Am J Sports Med 1983 Mar-Apr;11(2):58-62. doi: 10.1177/036354658301100202. PMID: 6846682

Diagnosis

Tendon appearance at imaging may be altered, but it may not indicate pathology.
Maffulli N, Nilsson Helander K, Migliorini F
Knee Surg Sports Traumatol Arthrosc 2023 May;31(5):1625-1628. Epub 2023 Feb 17 doi: 10.1007/s00167-023-07339-6. PMID: 36800008
Tenosynovial and Cardiac Amyloidosis in Patients Undergoing Carpal Tunnel Release.
Sperry BW, Reyes BA, Ikram A, Donnelly JP, Phelan D, Jaber WA, Shapiro D, Evans PJ, Maschke S, Kilpatrick SE, Tan CD, Rodriguez ER, Monteiro C, Tang WHW, Kelly JW, Seitz WH Jr, Hanna M
J Am Coll Cardiol 2018 Oct 23;72(17):2040-2050. doi: 10.1016/j.jacc.2018.07.092. PMID: 30336828
Rotator interval.
Woertler K
Semin Musculoskelet Radiol 2015 Jul;19(3):243-53. Epub 2015 May 28 doi: 10.1055/s-0035-1549318. PMID: 26021585
Subscapularis tendon tears.
Lyons RP, Green A
J Am Acad Orthop Surg 2005 Sep;13(5):353-63. doi: 10.5435/00124635-200509000-00009. PMID: 16148361
Elbow tendinopathy: tennis elbow.
Nirschl RP, Ashman ES
Clin Sports Med 2003 Oct;22(4):813-36. doi: 10.1016/s0278-5919(03)00051-6. PMID: 14560549

Therapy

ADSC-Based Cell Therapies for Musculoskeletal Disorders: A Review of Recent Clinical Trials.
Lee S, Chae DS, Song BW, Lim S, Kim SW, Kim IK, Hwang KC
Int J Mol Sci 2021 Sep 30;22(19) doi: 10.3390/ijms221910586. PMID: 34638927Free PMC Article
Patella Baja in Total Knee Arthroplasty.
Lum ZC, Saiz AM, Pereira GC, Meehan JP
J Am Acad Orthop Surg 2020 Apr 15;28(8):316-323. doi: 10.5435/JAAOS-D-19-00422. PMID: 31934927
Osteogenesis Imperfecta: A Pediatric Orthopedic Perspective.
Franzone JM, Shah SA, Wallace MJ, Kruse RW
Orthop Clin North Am 2019 Apr;50(2):193-209. doi: 10.1016/j.ocl.2018.10.003. PMID: 30850078
Endogenous ochronosis.
Turgay E, Canat D, Gurel MS, Yuksel T, Baran MF, Demirkesen C
Clin Exp Dermatol 2009 Dec;34(8):e865-8. doi: 10.1111/j.1365-2230.2009.03618.x. PMID: 20055850
Osteogenesis imperfecta.
Huber MA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Mar;103(3):314-20. Epub 2007 Jan 12 doi: 10.1016/j.tripleo.2006.10.003. PMID: 17223585

Prognosis

Tendon appearance at imaging may be altered, but it may not indicate pathology.
Maffulli N, Nilsson Helander K, Migliorini F
Knee Surg Sports Traumatol Arthrosc 2023 May;31(5):1625-1628. Epub 2023 Feb 17 doi: 10.1007/s00167-023-07339-6. PMID: 36800008
Inherited skin disorders presenting with poikiloderma.
Rayinda T, van Steensel M, Danarti R
Int J Dermatol 2021 Nov;60(11):1343-1353. Epub 2021 Mar 19 doi: 10.1111/ijd.15498. PMID: 33739439
Skewfoot.
Hagmann S, Dreher T, Wenz W
Foot Ankle Clin 2009 Sep;14(3):409-34. doi: 10.1016/j.fcl.2009.06.003. PMID: 19712883
Sotos syndrome.
Baujat G, Cormier-Daire V
Orphanet J Rare Dis 2007 Sep 7;2:36. doi: 10.1186/1750-1172-2-36. PMID: 17825104Free PMC Article
Subscapularis tendon tears.
Lyons RP, Green A
J Am Acad Orthop Surg 2005 Sep;13(5):353-63. doi: 10.5435/00124635-200509000-00009. PMID: 16148361

Clinical prediction guides

Tendon appearance at imaging may be altered, but it may not indicate pathology.
Maffulli N, Nilsson Helander K, Migliorini F
Knee Surg Sports Traumatol Arthrosc 2023 May;31(5):1625-1628. Epub 2023 Feb 17 doi: 10.1007/s00167-023-07339-6. PMID: 36800008
Anatomy, pathophysiology and classification of posterior tibial tendon dysfunction.
Guelfi M, Pantalone A, Mirapeix RM, Vanni D, Usuelli FG, Guelfi M, Salini V
Eur Rev Med Pharmacol Sci 2017 Jan;21(1):13-19. PMID: 28121362
Pediatric Thumb Flexion Deformities.
Shreve M, Chu A
Bull Hosp Jt Dis (2013) 2016 Mar;74(1):97-108. PMID: 26977555
Skewfoot.
Hagmann S, Dreher T, Wenz W
Foot Ankle Clin 2009 Sep;14(3):409-34. doi: 10.1016/j.fcl.2009.06.003. PMID: 19712883
Sotos syndrome.
Baujat G, Cormier-Daire V
Orphanet J Rare Dis 2007 Sep 7;2:36. doi: 10.1186/1750-1172-2-36. PMID: 17825104Free PMC Article

Recent systematic reviews

Brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS): new cases, systematic literature review, and associations with CSF1R-ALSP.
Dulski J, Souza J, Santos ML, Wszolek ZK
Orphanet J Rare Dis 2023 Jun 22;18(1):160. doi: 10.1186/s13023-023-02772-9. PMID: 37349768Free PMC Article
A systematic review of the reliability of diagnostic ultrasound imaging in measuring tendon size: Is the error clinically acceptable?
Mc Auliffe S, Mc Creesh K, Purtill H, O'Sullivan K
Phys Ther Sport 2017 Jul;26:52-63. Epub 2016 Dec 8 doi: 10.1016/j.ptsp.2016.12.002. PMID: 28162938
Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review.
Tilley BJ, Cook JL, Docking SI, Gaida JE
Br J Sports Med 2015 Dec;49(23):1504-9. Epub 2015 Oct 15 doi: 10.1136/bjsports-2015-095100. PMID: 26474596Free PMC Article
The sympathetic nervous system and tendinopathy: a systematic review.
Jewson JL, Lambert GW, Storr M, Gaida JE
Sports Med 2015 May;45(5):727-43. doi: 10.1007/s40279-014-0300-9. PMID: 25655371
The prevalence of the extensor indicis tendon and its variants: a systematic review and meta-analysis.
Yammine K
Surg Radiol Anat 2015 Apr;37(3):247-54. Epub 2014 Aug 6 doi: 10.1007/s00276-014-1352-0. PMID: 25096501

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