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Abnormal circulating creatinine concentration

MedGen UID:
866751
•Concept ID:
C4021101
•
Finding
Synonyms: Abnormal blood creatinine level; Abnormal circulating creatinine level; Creatinine levels abnormal
 
HPO: HP:0012100

Definition

An abnormal concentration of creatinine in the blood. [from HPO]

Professional guidelines

PubMed

Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.
Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y
ESC Heart Fail 2017 Nov;4(4):563-575. Epub 2017 Jun 27 doi: 10.1002/ehf2.12183. PMID: 29154418Free PMC Article
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai VB, Sakadjian A, Puthoff TD
Pharmacotherapy 2008 Sep;28(9):1162-82. doi: 10.1592/phco.28.9.1162. PMID: 18752387
Twenty-four hour hormonal and metabolic profiles in uraemic patients before and during treatment with continuous ambulatory peritoneal dialysis.
Heaton A, Johnston DG, Haigh JW, Ward MK, Alberti KG, Kerr DN
Clin Sci (Lond) 1985 Oct;69(4):449-57. doi: 10.1042/cs0690449. PMID: 4042546

Recent clinical studies

Etiology

Serum Annexin A2 concentrations are increased in patients with diabetic cardiomyopathy and are linked to cardiac dysfunctions.
He Q, Zhu J, Yang G, Liu X, Li L, Wang Y, Xiong X, Zheng Y, Zheng H, Qu H
Diabetes Res Clin Pract 2023 Jan;195:110196. Epub 2022 Dec 1 doi: 10.1016/j.diabres.2022.110196. PMID: 36464090
The imbalance of circulating monocyte subgroups with a higher proportion of the CD14+CD16+CD163+ phenotype in patients with preeclampsia.
Gong F, Wang J, Lu N, Wang J, Wang J, Shi X, Cui M, Cui L
Immunol Lett 2023 Jan;253:1-7. Epub 2022 Nov 29 doi: 10.1016/j.imlet.2022.11.005. PMID: 36460232
Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.
Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y
ESC Heart Fail 2017 Nov;4(4):563-575. Epub 2017 Jun 27 doi: 10.1002/ehf2.12183. PMID: 29154418Free PMC Article
Estimated glomerular filtration rate and urine biomarkers in patients with single-ventricle Fontan circulation.
Opotowsky AR, Baraona FR, Mc Causland FR, Loukas B, Landzberg E, Landzberg MJ, Sabbisetti V, Waikar SS
Heart 2017 Mar;103(6):434-442. Epub 2016 Sep 26 doi: 10.1136/heartjnl-2016-309729. PMID: 27670967Free PMC Article
Serum concentrations and peritoneal loss of growth hormone and growth-hormone-binding protein activity in older adults undergoing continuous ambulatory peritoneal dialysis: comparison with haemodialysis patients and normal subjects.
Kagan A, Zadik Z, Gertler A, Ulman M, Bar-Khayim Y
Nephrol Dial Transplant 1993;8(4):352-6. PMID: 8390011

Diagnosis

Serum Annexin A2 concentrations are increased in patients with diabetic cardiomyopathy and are linked to cardiac dysfunctions.
He Q, Zhu J, Yang G, Liu X, Li L, Wang Y, Xiong X, Zheng Y, Zheng H, Qu H
Diabetes Res Clin Pract 2023 Jan;195:110196. Epub 2022 Dec 1 doi: 10.1016/j.diabres.2022.110196. PMID: 36464090
The imbalance of circulating monocyte subgroups with a higher proportion of the CD14+CD16+CD163+ phenotype in patients with preeclampsia.
Gong F, Wang J, Lu N, Wang J, Wang J, Shi X, Cui M, Cui L
Immunol Lett 2023 Jan;253:1-7. Epub 2022 Nov 29 doi: 10.1016/j.imlet.2022.11.005. PMID: 36460232
Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.
Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y
ESC Heart Fail 2017 Nov;4(4):563-575. Epub 2017 Jun 27 doi: 10.1002/ehf2.12183. PMID: 29154418Free PMC Article
Estimated glomerular filtration rate and urine biomarkers in patients with single-ventricle Fontan circulation.
Opotowsky AR, Baraona FR, Mc Causland FR, Loukas B, Landzberg E, Landzberg MJ, Sabbisetti V, Waikar SS
Heart 2017 Mar;103(6):434-442. Epub 2016 Sep 26 doi: 10.1136/heartjnl-2016-309729. PMID: 27670967Free PMC Article
Disordered FGF23 and mineral metabolism in children with CKD.
Portale AA, Wolf M, Jüppner H, Messinger S, Kumar J, Wesseling-Perry K, Schwartz GJ, Furth SL, Warady BA, Salusky IB
Clin J Am Soc Nephrol 2014 Feb;9(2):344-53. Epub 2013 Dec 5 doi: 10.2215/CJN.05840513. PMID: 24311704Free PMC Article

Therapy

Markers of peripheral perfusion during high-flow regional cerebral perfusion for aortic arch repair.
Sughimoto K, Kohira S, Hayashi H, Torii S, Kitamura T, Horai T, Miyaji K
J Thorac Cardiovasc Surg 2018 Dec;156(6):2251-2257. Epub 2018 Sep 28 doi: 10.1016/j.jtcvs.2018.08.097. PMID: 30449581
Polycystic Kidney Disease and the Vasopressin Pathway.
van Gastel MDA, Torres VE
Ann Nutr Metab 2017;70 Suppl 1:43-50. Epub 2017 Jun 15 doi: 10.1159/000463063. PMID: 28614813
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai VB, Sakadjian A, Puthoff TD
Pharmacotherapy 2008 Sep;28(9):1162-82. doi: 10.1592/phco.28.9.1162. PMID: 18752387
Hepatorenal syndrome: emerging perspectives of pathophysiology and therapy.
Epstein M
J Am Soc Nephrol 1994 Apr;4(10):1735-53. doi: 10.1681/ASN.V4101735. PMID: 8068872
Lithium: a review of its pharmacokinetics, health effects, and toxicology.
Marcus WL
J Environ Pathol Toxicol Oncol 1994;13(2):73-9. PMID: 7884646

Prognosis

Serum Annexin A2 concentrations are increased in patients with diabetic cardiomyopathy and are linked to cardiac dysfunctions.
He Q, Zhu J, Yang G, Liu X, Li L, Wang Y, Xiong X, Zheng Y, Zheng H, Qu H
Diabetes Res Clin Pract 2023 Jan;195:110196. Epub 2022 Dec 1 doi: 10.1016/j.diabres.2022.110196. PMID: 36464090
Markers of peripheral perfusion during high-flow regional cerebral perfusion for aortic arch repair.
Sughimoto K, Kohira S, Hayashi H, Torii S, Kitamura T, Horai T, Miyaji K
J Thorac Cardiovasc Surg 2018 Dec;156(6):2251-2257. Epub 2018 Sep 28 doi: 10.1016/j.jtcvs.2018.08.097. PMID: 30449581
Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.
Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y
ESC Heart Fail 2017 Nov;4(4):563-575. Epub 2017 Jun 27 doi: 10.1002/ehf2.12183. PMID: 29154418Free PMC Article
Disordered FGF23 and mineral metabolism in children with CKD.
Portale AA, Wolf M, Jüppner H, Messinger S, Kumar J, Wesseling-Perry K, Schwartz GJ, Furth SL, Warady BA, Salusky IB
Clin J Am Soc Nephrol 2014 Feb;9(2):344-53. Epub 2013 Dec 5 doi: 10.2215/CJN.05840513. PMID: 24311704Free PMC Article
Hepatorenal syndrome: emerging perspectives of pathophysiology and therapy.
Epstein M
J Am Soc Nephrol 1994 Apr;4(10):1735-53. doi: 10.1681/ASN.V4101735. PMID: 8068872

Clinical prediction guides

Serum Annexin A2 concentrations are increased in patients with diabetic cardiomyopathy and are linked to cardiac dysfunctions.
He Q, Zhu J, Yang G, Liu X, Li L, Wang Y, Xiong X, Zheng Y, Zheng H, Qu H
Diabetes Res Clin Pract 2023 Jan;195:110196. Epub 2022 Dec 1 doi: 10.1016/j.diabres.2022.110196. PMID: 36464090
Markers of peripheral perfusion during high-flow regional cerebral perfusion for aortic arch repair.
Sughimoto K, Kohira S, Hayashi H, Torii S, Kitamura T, Horai T, Miyaji K
J Thorac Cardiovasc Surg 2018 Dec;156(6):2251-2257. Epub 2018 Sep 28 doi: 10.1016/j.jtcvs.2018.08.097. PMID: 30449581
Disordered FGF23 and mineral metabolism in children with CKD.
Portale AA, Wolf M, Jüppner H, Messinger S, Kumar J, Wesseling-Perry K, Schwartz GJ, Furth SL, Warady BA, Salusky IB
Clin J Am Soc Nephrol 2014 Feb;9(2):344-53. Epub 2013 Dec 5 doi: 10.2215/CJN.05840513. PMID: 24311704Free PMC Article
Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem.
Arroyo V, Jiménez W
J Hepatol 2000;32(1 Suppl):157-70. doi: 10.1016/s0168-8278(00)80423-7. PMID: 10728802
Serum concentrations and peritoneal loss of growth hormone and growth-hormone-binding protein activity in older adults undergoing continuous ambulatory peritoneal dialysis: comparison with haemodialysis patients and normal subjects.
Kagan A, Zadik Z, Gertler A, Ulman M, Bar-Khayim Y
Nephrol Dial Transplant 1993;8(4):352-6. PMID: 8390011

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