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Intestinal hypoplasia

MedGen UID:
867279
•Concept ID:
C4021640
•
Finding
Synonyms: Hypoplastic intestines; Underdeveloped instestine
 
HPO: HP:0005245

Definition

Developmental hypoplasia of the intestine. [from HPO]

Conditions with this feature

Martinez-Frias syndrome
MedGen UID:
318628
•Concept ID:
C1832443
•
Disease or Syndrome
The Martinez-Frias syndrome is characterized by pancreatic hypoplasia, intestinal atresia, and gallbladder aplasia or hypoplasia, with or without tracheoesophageal fistula. There is considerable phenotypic overlap between Martinez-Frias syndrome and Mitchell-Riley syndrome (MTCHRS; 615710), the latter being characterized by neonatal diabetes in addition to the features of the Martinez-Frias syndrome, but without tracheoesophageal fistula (Smith et al., 2010).
See: Condition Record
Martinez-Frias syndrome

Professional guidelines

PubMed

AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Evidence-based clinical practice guidelines for inflammatory bowel disease 2020.
Nakase H, Uchino M, Shinzaki S, Matsuura M, Matsuoka K, Kobayashi T, Saruta M, Hirai F, Hata K, Hiraoka S, Esaki M, Sugimoto K, Fuji T, Watanabe K, Nakamura S, Inoue N, Itoh T, Naganuma M, Hisamatsu T, Watanabe M, Miwa H, Enomoto N, Shimosegawa T, Koike K
J Gastroenterol 2021 Jun;56(6):489-526. Epub 2021 Apr 22 doi: 10.1007/s00535-021-01784-1. PMID: 33885977Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

Recent clinical studies

Therapy

Biologic properties and therapeutic potential of glucagon-like peptide-2.
Drucker DJ, Boushey RP, Wang F, Hill ME, Brubaker PL, Yusta B
JPEN J Parenter Enteral Nutr 1999 Sep-Oct;23(5 Suppl):S98-100. doi: 10.1177/014860719902300524. PMID: 10483906
Intestinal morphological changes during oral refeeding in a patient previously treated with total parenteral nutrition for small bowel resection.
Biasco G, Callegari C, Lami F, Minarini A, Miglioli M, Barbara L
Am J Gastroenterol 1984 Aug;79(8):585-8. PMID: 6431800

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