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Increased T cell count

MedGen UID:
867575
•Concept ID:
C4021960
•
Finding
Synonyms: Increase in T cell count; Increase in T cell number
 
HPO: HP:0100828

Definition

An abnormal increase in the total number of T cells detected in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased T cell count

Professional guidelines

PubMed

A retrospective clinical study of dolutegravir- versus efavirenz-based regimen in treatment-naïve patients with advanced HIV infection in Nanjing, China.
Zhong M, Li M, Qi M, Su Y, Yu N, Lv R, Ye Z, Zhang X, Xu X, Cheng C, Chen C, Wei H
Front Immunol 2022;13:1033098. Epub 2023 Jan 9 doi: 10.3389/fimmu.2022.1033098. PMID: 36700216Free PMC Article
Prevalence of syphilis among people living with HIV and its implication for enhanced coinfection monitoring and management in China: A meta-analysis.
Wu Y, Zhu W, Sun C, Yue X, Zheng M, Fu G, Gong X
Front Public Health 2022;10:1002342. Epub 2022 Oct 17 doi: 10.3389/fpubh.2022.1002342. PMID: 36324449Free PMC Article
Treatment outcomes and characteristics of HIV-2 patients compared to HIV-1 patients on an NNRTI-based first line art at the adult infectious diseases centre of the University Teaching Hospital (UTH) in Lusaka.
Bhebhe AT, Chongwe G, Moonga G
Pan Afr Med J 2021;40:231. Epub 2021 Dec 16 doi: 10.11604/pamj.2021.40.231.25149. PMID: 35178142Free PMC Article

Recent clinical studies

Etiology

Human natural killer T cells (NKT), NK and T cells in pulmonary tuberculosis: potential indicators for disease activity and prognosis.
Zahran WA, Ghonaim MM, Koura BA, El-Banna H, Ali SM, El-Sheikh N
Egypt J Immunol 2006;13(1):67-78. PMID: 17974151
Sezary syndrome: cutaneous immunoperoxidase double-labeling technique demonstrates CD4/CD8 ratio non-specificity.
Balfour EM, Glusac EJ, Heald P, Talley LL, Smoller BR
J Cutan Pathol 2003 Aug;30(7):437-42. doi: 10.1034/j.1600-0560.2003.00059.x. PMID: 12859741

Diagnosis

Human natural killer T cells (NKT), NK and T cells in pulmonary tuberculosis: potential indicators for disease activity and prognosis.
Zahran WA, Ghonaim MM, Koura BA, El-Banna H, Ali SM, El-Sheikh N
Egypt J Immunol 2006;13(1):67-78. PMID: 17974151
Sezary syndrome: cutaneous immunoperoxidase double-labeling technique demonstrates CD4/CD8 ratio non-specificity.
Balfour EM, Glusac EJ, Heald P, Talley LL, Smoller BR
J Cutan Pathol 2003 Aug;30(7):437-42. doi: 10.1034/j.1600-0560.2003.00059.x. PMID: 12859741

Therapy

A patient with paroxysmal nocturnal haemoglobinuria in whom granulocyte colony-stimulating factor administration resulted in improvement of recurrent enterocolitis and its associated haemolytic attacks.
Fujimi A, Matsunaga T, Kogawa K, Ohnuma T, Takahira N, Abe T, Kitaoka K, Kogawa T, Tanaka I, Morii K, Terui T, Sakamaki S, Kato J, Kura T, Maeda T, Niitsu Y
Br J Haematol 2002 Dec;119(3):858-62. doi: 10.1046/j.1365-2141.2002.03914.x. PMID: 12437672

Prognosis

Human natural killer T cells (NKT), NK and T cells in pulmonary tuberculosis: potential indicators for disease activity and prognosis.
Zahran WA, Ghonaim MM, Koura BA, El-Banna H, Ali SM, El-Sheikh N
Egypt J Immunol 2006;13(1):67-78. PMID: 17974151

Clinical prediction guides

Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice.
Lu L, Li T, Feng X, Liu Z, Liu Y, Chao T, Gu Y, Huang R, Zhang F, He L, Zhou B, Kong E, Liu Z, Wang X, Chen Z, Wang H, Malissen M, Malissen B, Zhang L, Liang Y
PLoS Pathog 2022 Jun;18(6):e1010596. Epub 2022 Jun 6 doi: 10.1371/journal.ppat.1010596. PMID: 35666747Free PMC Article
Human natural killer T cells (NKT), NK and T cells in pulmonary tuberculosis: potential indicators for disease activity and prognosis.
Zahran WA, Ghonaim MM, Koura BA, El-Banna H, Ali SM, El-Sheikh N
Egypt J Immunol 2006;13(1):67-78. PMID: 17974151

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